Beuzón & Ruiz-Albert Lab

🎓 Hoy nuestra doctoranda Laura Mancera Miranda ha leído su tesis titulada "DNA methylation and mtases in plant pathogenic 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘴𝘺𝘳𝘪𝘯𝘨𝘢𝘦", dirigida por nuestros investigadores Carmen Beuzón y Javier Ruiz Albert (@type3lab.bsky.social)

✨ ¡Enhorabuena, Laura! ✨

Salicylic acid biosensor, SalicS1, tracks the plant immune hormone salicylic acid in real time - revealing propagation of hormone surge during plant pathogen advance

Latest biosensor from @xanderjones.bsky.social team
In Science doi.org/10.1126/scie...
Summary www.slcu.cam.ac.uk/news/new-bio...

SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled...

FRET sensor for SA developed. www.science.org/doi/10.1126/...

A vinyl box with six colored vinyl LPs sticking out of its right side. The Title "Guns in Rosettes" is on top, with the subtitle "The Arabidopsis chemical weapons arsenal" just below. Then there is an Arabidopsis plant with machine guns sticking out. Below is the statement "6-LP LIMITED EDITION COLORED VINYL BOX SET"

The back cover of the vinyl box set showing the tracklist: 1. Methionine-derived compounds Aliphatic GSLs 2. Tryptophan-derived compounds (trptonites) Indolic GSLs Camalexin Hycanite (4-OH-ICN) 3. Phenylalanine-derived compounds (phenylpropanoids) Benzenic GSLs Coumarins Hydroxycinnamates Flavonoids 4. Terpenoids (E)-β-caryophyllene α- and β-pinene Thalianin, arabidin, and DMNT And the statement "Recorded live in front of an audience in 2025"

Our article "Guns in Rosettes: The Arabidopsis chemical weapons arsenal" is finally published @plantphys.bsky.social!
You can download the #OpenAccess PDF here:

doi.org/10.1093/plph...

But real connoisseurs of #AntimicrobialCompounds will want to get the vinyl boxset: #PlantScience #PlantImmunity

Spatial architecture of development and disease - Nature Reviews Genetics Spatial omics has empowered the discovery of developmental and disease-associated molecular signatures, cell states and multicellular niches, as well as the evaluation of disease heterogeneity within and across organs. The authors review spatially resolved molecular changes across diseases and discuss the potential of spatial multi-omics for clinical applications, including the recent impact of artificial intelligence.

Spatial architecture of development and disease
go.nature.com/477Dmxs
#Review by Enikő Lázár & Joakim Lundeberg
Free to read here: rdcu.be/eJ9E4

Congratulations to the new Doctor in the lab, Álvaro Jiménez-Jiménez. Fantastic defense work!! 🧑‍🎓🥳

Congrats Alvaro (and supervisors)!

👏 THESIS DEFENSE
👉 "DNA methylation and mtases in plant pathogenic 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘴𝘺𝘳𝘪𝘯𝘨𝘢𝘦"
🤝 By Laura Mancera Miranda and directed by Carmen Beuzón and Javier Ruiz Albert (@type3lab.bsky.social)

📅 Tomorrow at 11 AM
📌 IHSM La Mayora Auditorium (Bulevar Louis Pasteur, 49. Málaga)

tRNA-modifying enzymes in bacterial stress adaptation | Open Biology Transfer RNAs (tRNAs) and their modifications are central to bacterial translation and physiology, yet their roles in stress adaptation remain underexplored. While extensively studied in eukaryotes, a...

Happy to share our new review in Royal Society Open Biology 🎉
tRNA-modifying enzymes in bacterial stress adaptation:
How tRNA mods rewire translation under oxidative + antibiotic stress (MoTTs, moonlighting, therapy angles).
Read: doi.org/10.1098/rsob...
#RNAsky #microsky #AMR #RNAmodifications

🔬 Caracteriza el circuito regulador de la heterogeneidad fenotípica del T3SS en Pseudomonas syringae. (JAEINT25_EX_0440) con el investigador Javier Ruiz.
www.ihsm.uma-csic.es/investigador...

🎉 Enhorabuena a todos los estudiantes que han conseguido una beca #JAEIntro del @csic.es 👏.
🚨 Ahora que llega el momento de elegir grupo, recordad que el IHSM La Mayora ofrece 11 proyectos diferentes para realizar estas prácticas 🌱🧬🦠

📚 Consulta los planes formativos que ofertamos 👇

Map of bacterial gene interactions uncovers targets for future antibiotics Despite rapid advances in reading the genetic code of living organisms, scientists still face a major challenge today—knowing a gene's sequence does not automatically reveal what it does. Even in…

Map of #bacterial gene interactions uncovers targets for future #antibiotics ...

| #bacteria | #microbes | #genes | #geneticcode | Via @sciencex.bsky.social

This morning Wenbo Ma, senior group leader at TSL, gave the first talk at our Annual Science Meeting, one of the highlights of our scientific year!

Find out more about the Ma lab: tsl.ac.uk/our-work/sci...

@johninnescentre.bsky.social

Our paper, describing how the T6SSs of P. putida shape the tomato rhizosphere, is now in its final format in @isme-microbes.bsky.social ISME Communications. If you'd like to learn more, here is a thread (1/11) or read the Article doi.org/10.1093/isme....

🌱🎓 Last Friday we enjoyed another great talk whithin the 2025-2026 #SeminarSeriesCBGP season!

🗣️ Laura Arribas-Hernández from the @ihsmumacsic.bsky.social shared insights on the 'Epitranscriptomic regulation of plant development'!

Thanks to everyone who joined us! 🚀

#PlantScience

Localized glutamine leakage drives the spatial structure of root microbial colonization Plant roots release exudates to encourage microbiome assembly, which influences the function and stress resilience of plants. How specific exudates drive spatial colonization patterns remains largely ...

A long road to the Cover of Science!
www.science.org/doi/10.1126/...

Nice brief @laura-ah.bsky.social

Too hot to defend: elevated temperature compromises systemic acquired resistance Click on the article title to read more.

Thank you very much to Editor Martin Balcerowicz (@transcription.bsky.social) for highlighting our work in the September issue of @theplantjournal.bsky.social!

Article: doi.org/10.1111/tpj....
Research Highlight: doi.org/10.1111/tpj....

@laurierbiology.bsky.social @cspbscbv.bsky.social

The Ralstonia solanacearum effector RipAV targets plant U-box proteins and induces proteasomal-dependent degradation of BIK1
New Phytologist (@newphyt.bsky.social)
👉 doi.org/10.1111/nph....

Response to “The action of Arabidopsis DICER-LIKE2 in plant growth inhibition”
The Plant Cell (@theplantcell.bsky.social)
👉 doi.org/10.1093/plce...

Tailored translation: Local tRNA activation to match protein composition needs Both DNA and proteins are formed by a succession of chemical elements that, like the letters inside a sentence, are arranged in sequences. But because they

Tailored translation: Local tRNA activation to match protein composition needs
The Plant Cell (@theplantcell.bsky.social)
👉 doi.org/10.1093/plce...

The nuclear pore complex acts as a hub for pri-miRNA transcription and processing in plants
Nucleic Acids Research
👉 doi.org/10.1093/nar/...

We’re filming our new institutional video at IHSM Mayora! 🎥🌱🎬

We’ll post it on our website (www.ihsm.uma-csic.es) as soon as it’s ready; stay tuned!

Injectisome assembly primes Pseudomonas aeruginosa for Type III secretion Many Gram-negative pathogens, including Pseudomonas aeruginosa , use a Type III Secretion System (T3SS) to intoxicate eukaryotic cells. The T3SS is an important virulence factor linked to increased mo...

Injectisome assembly primes Pseudomonas aeruginosa for Type III secretion
www.biorxiv.org/content/10.1...

A bacterial signal coordinates plant-microbe fitness trade-off to enhance sulfur deficiency tolerance in plants Mukherjee et al. report fitness trade-off between plants and the rhizosphere microbiome under sulfur deficiency, mediated by the tri-peptide signal glutathione. Competition among rhizosphere bacteria ...

A bacterial signal coordinates plant-microbe fitness trade-off to enhance sulfur deficiency tolerance in plants: Cell Host & Microbe www.cell.com/cell-host-mi...

📰 RNA Modifications Newsletter – October 1st, 2025 issue #4

New RNA Modifications Newsletter (October) is out! 🚀 open.substack.com/pub/rnamodif...

#HiringCBGP ‼️

🌱 The Center for Plant Biotechnology & Genomics (CBGP, UPM-INIA/CSIC) is #hiring!

We’re seeking a Head of the Translational Biology Unit/Knowledge Transfer Office to drive innovation, IP protection & industry partnerships.

📍 Apply now: shorturl.at/wI8IW

📢 A Junior Professorship (W1, tenure track) is open at the Center for Plant Molecular Biology at Uni Tübingen (@zmbp-tuebingen.bsky.social) — to work on plant protein biochemistry (composition, structure, dynamics, or regulation of protein complexes). 🌱 Great opportunity — Apply by Oct 17th!

Widespread deployment of the human CD38 ADP-ribosyl cyclase fold in antibacterial and anti-eukaryotic polymorphic toxins Bacterial polymorphic toxins are modular weapons that mediate inter-microbial competition and host interactions by delivering diverse cytotoxic domains through specialized secretion systems. Here, we ...

Happy to share our work on a T6SS effector with ADP ribose cyclase activity, published in JBC @asbmbjournals.bsky.social
Great work of Julius Martinkus @jmartinkus.bsky.social and (always) great collaboration with @dukasju.bsky.social and @laurentterradot.bsky.social
www.jbc.org/article/S002...

Open position !!
Either at the Engineer or post-doctoral level, to work on filamentous phages. Collaboration between Laetitia Houot's group and Thierry Doan @thicoz.bsky.social.
To apply at the E level:
emploi.cnrs.fr/Offres/CDD/U...
To apply at the post-doc level:
emploi.cnrs.fr/Offres/CDD/U...