David A. Salamanca-Diaz

a, Global average temperature and the timing of large igneous province (LIP). Modified from ref. 108. b, Palaeo-ocean acidification events during the Mesozoic and Cenozoic. Solid red lines represent confirmed ocean acidification events. Dashed orange lines represent disputed ocean acidification events. c, Morphological simplification in brachiopods and foraminifera reduces the increased calcification energy caused by ocean acidification across the PTME and T-OAE in this study. AOAE, Aptian oceanic anoxic event; CALIP, Central Atlantic LIP; COAE, Cenomanian oceanic anoxic event; DLIP, Deccan LIP; KFLIP, Karoo-Ferrar LIP; KPgME, Cretaceous–Palaeogene mass extinction; NALIP, North Atlantic LIP; N-MLIP, Naturaliste-Madagascar LIP; PETM, Paleocene-Eocene Thermal Maximum; STLIP, Siberian Traps LIP; TJME, Triassic–Jurassic mass extinction.

Around extinction events, the shape of shells of certain groups becomes simpler. It's a sort of austerity measure to reduce the energy cost associated with producing a shell. Might be something we need to keep an eye out for in marine organisms now. 🧪🌊

Link: www.nature.com/articles/s41...

Join our "Advances in Single-Cell Technologies" meeting in December in Freiburg, co-organised with Marco Prinz and @katrinkierdorf.bsky.social. Excellent line-up of speakers covering spatial technologies, lineage tracing, computational methods, and more.
www.uniklinik-freiburg.de/single-cell-...

Are you a PI in a biology field looking for postdocs? Here is a Starter Pack of early career biologists currently seeking postdoctoral positions! (Also if you are searching for a postdoc, let me know if you want to be added!) go.bsky.app/8zZNEGV

This is a really cool idea to make use of bluesky! Can I be added?

A single-cell ATACseq atlas of our favourite sea anemone, Nematostella vectensis! By @aelek.bsky.social @martaig.bsky.social

An episodic burst of massive genomic rearrangements and the origin of non-marine annelids - Nature Ecology & Evolution An analysis of annelid genomes reveals massive reshuffling of chromosomes in the ancestral lineage leading to clitellates, a clade composed of non-marine annelids, with potential implications for the ...

Glad to see this paper finally out! An episodic burst of massive genomic rearrangements and the origin of non-marine annelids
@natecoevo.nature.com @ibe-barcelona.bsky.social @csic.es @erc.europa.eu www.nature.com/articles/s41...

Chordin-mediated BMP shuttling patterns the secondary body axis in a cnidarian Chordin-mediated BMP shuttling is the candidate mechanism for generating bilateral symmetry in the cnidarian-bilaterian ancestor.

David’s @davidmoersdorf.bsky.social cool paper about the role of Chordin in BMP signaling in the sea anemone Nematostella is finally out www.science.org/doi/10.1126/...

The anti-neural role of BMP signaling is a side effect of its global function in dorsoventral patterning In Bilateria with centralized nervous systems (e.g. in vertebrates or arthropods), the minimum of the BMP signaling activity gradient defines the position of the central nervous system. BMP-dependent ...

The last part of @paulknabl.bsky.social 's PhD is now available at www.biorxiv.org/content/10.1...
Paul showed that BMP signaling is active in the diffuse nervous system of the sea anemone Nematostella and the box jellyfish Tripedalia. Moreover, suppression of BMP signaling in Nematostella leads...

I’ve been studying gene regulation in primates for over 20 years, and using RNA-seq since 2008 to compare expression across species. We thought we were being careful. We used curated orthologous exons to minimize alignment bias and focused on biologically meaningful comparisons.

We were wrong.

ATAC‐seq in Emerging Model Organisms: Challenges and Strategies Principle of ATAC-seq (left), overview of arthropod species with published ATAC-seq data (middle), summary of experimental design (right).

You want to apply #ATACseq in your emerging model organism, but you don't know where to start? Is #ATACseq the best method for my research questions? Search no more! We got you covered with our new review: doi.org/10.1002/jez.... Excellent collaboration with @gevol.bsky.social

Analyzing your single-cell data by mapping to a reference atlas? Then how do you know the mapping actually worked, and you’re not analyzing mapping-induced artifacts? We developed mapQC, a mapping evaluation tool www.biorxiv.org/content/10.1... from the ‪@fabiantheis lab. Let’s dive in🧵

It's finally here! Great start of the summer. We got our latest preprint from @chemamd.bsky.social in @qmulsbbs.bsky.social @qmulse.bsky.social, showing evidence of developmental system drift in the specification of dorsoventral (belly vs back) axis in annelids 🪱🪱🪱
#DevBio #EvoDevo

Congrats Tim!!

Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of genome architecture and spatial genome regulation emerged early in animal evolution.

Nature research paper: Chromatin loops are an ancestral hallmark of the animal regulatory genome

https://go.nature.com/4kcNObU

Proud to present the peer-reviewed version of our Cell Type Allometry paper, out today in Science Advances!

www.science.org/doi/10.1126/...

Are animals of different sizes made of the same cell types?

Here’s an update of the main points and revision items

(with memes!)

Thread 👇🧵

A digital drawing with dark blue text above saying “protect the” and the bottom text saying “weirdos”. There are four animals in between the text. The top left is a green and brown horned frog (aka Pac-Man frog). The top right is a pink and white flea beetle. The bottom left is a yellow slug. The bottom right is a kingsnake with grey and red scales. The background is light blue.

Last day of #invertefest so let’s end with one of my most popular pieces of art!

linktr.ee/squishyfauna

#invertebrates #bugsky #bugs #entomology #insects #herps #frogs #snakes #sciart #bsnm

Molluscan Shells, Spicules, and Gladii Are Evolutionarily Deeply Conserved Evolutionarily conserved transcription factor encoding genes and other genes are expressed in the epithelia that give rise to spicules (green) and/or shells (blue) in developmental stages of diverse ...

Finally out - our paper on shell field and spicule #EvoDevo in a variety of #mollusks such as #scaphopods, #cephalopods, #aplacophorans, and of course #polyplacophorans. Among others we show evolutionary highly conserved gene expression in aculiferan spicules onlinelibrary.wiley.com/doi/10.1002/...

Time magazine cover showing Remus, a genetically modified grey wolf claimed to be a "dire wolf." The headline reads: "This is Remus. He's a dire wolf. The first to exist in over 10,000 years. Endangered species could be changed forever."

Public service announcement: this is *not* a dire wolf.

It is a genetically modified grey wolf made to resemble an extinct species, so a bullshit company can raise more money for their bullshit projects.

#Deextinction is a scam on so many levels I don't even […]

[Original post on spore.social]

What Existentialism Still Has to Teach Us About the Quest for a Meaningful Life This year marks the 80th anniversary of the birth of existentialism in France. Indeed, it would never have been born had France not known war and defeat by Nazi Germany. Those who had resisted under t...

Existentialism and a meaningful life - by Robert Zaretsky www.templeton.org/news/what-ex...

CREsted: modeling genomic and synthetic cell type-specific enhancers across tissues and species Sequence-based deep learning models have become the state of the art for the analysis of the genomic regulatory code. Particularly for transcriptional enhancers, deep learning models excel at decipher...

A nice comprehensive package for genomic modeling!

CREsted: modeling genomic and synthetic cell type-specific enhancers across tissues and species

www.biorxiv.org/content/10.1...

While we’re banning books…

Finland is teaching children in school how to recognize fake news and propaganda as part of critical thinking and civic responsibility. Some of this will seem very familiar.

Be. Like. Finland.

One of my favorite feelings is the joy of learning about an astonishing creature I previously had no idea existed. Most recent ex: the shingle urchin, which I initially mistook for a 3D printed aquarium ornament. Look at that iridescent mosaic of flattened spines!

🎥TikTok user discover.aquatics

Worm Vs. Ctenophore!
A predatory Tomopteris worm has stalked and captured a Ctenophore (aka “comb jelly”).
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#ctenophore #combjelly #plankton #blackwater #chrisgug #gugunderwater #gug

English version of the documentary about power abuse in the Max Planck Society can be found here. 144.000 views already, more than 800 comments. Share it to make colleagues aware of what happens in German academia & the MPG! #IchBinHanna #PowerAbuse

Small, perky snail with head poking out between its two shells. The snail has a pair of long, tubular tentacles. The shells are like clam shells, except they are vivid green. The hinge is at the top. Julia exquisita: Kwajalein Atoll, Marshall Islands. © uwkwaj CC BY-NC https://www.inaturalist.org/photos/166680082

In this photo, the snail is lying on its side with the hinge of the two shells pointing towards the camera. The shell and snail are both very bright green. The snail has white blotches on its back. Julia exquisita: Kwajalein Atoll, Marshall Islands. © uwkwaj CC BY-NC https://www.inaturalist.org/photos/263219540

We’ve looked at snails with one shell and slugs with no shells. Now let’s have a look at a snail with two shells, because Nature laughs at our puny attempts to pigeonhole.

In today’s #AtoZ – J is for Julia (Juliidae) (1/9)

Pic: © uwkwaj CC BY-NC

A pea-sized #Argonaut octopus rides atop a stinging #siphonophore through the nighttime open ocean.
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Shot several miles off West Palm Beach, FL, USA.
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#papernautilus #nautilus #cephalopod #plankton #blackwater #blackwaterphotography #blackwaterdiving #gug #chrisgug #gugunderwater #underwater

Also to you on your fellowship, that is huge!!!🎉

Is public!! great work everyone, couldn't have built such an incredible story without you!
@hrhorkan.bsky.social @thecocodium.bsky.social @jordisolana.bsky.social

An oval squid (Sepioteuthis lessoniana) hovers in a nighttime sea, displaying its natural iridescence. This species is among those informing new insights into molluscan evolution. The extreme diversity in the phylum Mollusca—which includes squids, chitons, snails, clams, and others—has long puzzled scientists. Sequencing previously uncharacterized genomes helps to resolve the molluscan family tree.

From octopuses to snails, the complicated molluscan family tree has now been mapped in unprecedented detail, researchers report in Science.

Learn more in this week's issue: scim.ag/4hVhrxB

A whole-body atlas of BMP signaling activity in an adult sea anemone - BMC Biology Background BMP signaling is responsible for the second body axis patterning in Bilateria and in the bilaterally symmetric members of the bilaterian sister clade Cnidaria—corals and sea anemones. Howev...

Our atlas of BMP signaling activity in adult Nematostella is finally out! Fantastic, meticulous work and beautiful illustrations by @paulknabl.bsky.social
Thanks, @fwf-at.bsky.social for funding our work!
bmcbiol.biomedcentral.com/articles/10....