Felipe Opazo

- A postdoc to work on cancer extravasation (4-year project).
- A postdoc help in completing Filopodia-related lab projects (2-year).
- Multiple Marie Curie postdoc positions that will open in the fall.
- We will open a 5-year position to cover my teaching (70% research and 30% teaching).

🌞🦙 Summer makeover? You bet.
Our alpacas ditched the fleece to stay cool – maybe your antibodies should too.
sdAbs are high-performance tools made of just the antigen-binding domain (∼15 kDa, 3 nm). 🔬🧪Perfect for IF, super-resolution microscopy, IP & more.
Browse our #nanobodies: nano-tag.com/shop/

💬Thank you, Dr. Maja Klevanski @majaklevanski.bsky.social (University of Heidelberg), for the great feedback on our recombinant anti-SARS-CoV-2 S1 antibody (rHcAb)! 😊 🔬 Applied in #dSTORM to study virion–cell interactions under antiviral conditions. Learn more about sdAb–Fc fusions 👉 bit.ly/3xdhYsn

🤹‍♀️ Still juggling primary antibodies from different species?
Still stuck in sequential staining?

⏱️Switch to Smart Secondaries®🦙:
✅OneStep-IF
✅Same-species #multiplexing
✅Higher precision & reproducibility!

Choose smart 👉 bit.ly/3UZxRMI

#SecondaryNanobody #Microscopy #Immunofluorescence

Yes, it might be that in some synaptic type, other synaptotagmin isoforms are more dominant, but it is far from demonstrated that there is NO Syt1 in such synapses...

A Versatile Synaptotagmin‐1 Nanobody Provides Perturbation‐Free Live Synaptic Imaging And Low Linkage‐Error in Super‐Resolution Microscopy Selection, characterization, and development of a nanobody that strongly and selectively binds the C2A domain of synaptotagmin-1, providing unparalleled imaging accuracy in various super-resolution i...

Try our anti-Synaptotagmin1 #nanobody, then you label endogenous targets without adding extra copies of anything synaptic. We can send you the AAV plasmids. Check paper here: onlinelibrary.wiley.com/doi/10.1002/...

@abberior.rocks — and NanoTag Biotechnologies rocks with them! 🤘

Smart Secondaries® 🦙now conjugated to abberior STAR dyes 🌈. Discover brighter, sharper, #STED -ready, species-independent #multiplexing & one-step IF. 🔬🤩

#SecondaryNanobodies
#SuperResolution
#FluorescenceMicroscopy

Congrats, nice work! Clever use of the ALFA system!

Preprint: IntAct-U-ExM enables robust, isoform-specific expansion microscopy of actin networks in yeast and mammalian cells. A cool study led by @anubhavdhar.bsky.social in collaboration with Sudarshan and Deepak Nair. www.biorxiv.org/content/10.1...

Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution - Nature Communications Extracting quantitative information on biomolecular oligomerisation with high resolution remains a significant challenge. Here, the authors propose SPINNA, a framework that compares nearest-neighbour ...

A new study by @jungmannlab.bsky.social presents #SPINNA, a model-based tool for quantifying protein stoichiometry, oligomerization state, and spatial arrangement from super-resolution data.🔬For precise labeling of #GFP & #mCherry fusion proteins researchers used our #nanobodies 😊
📄 bit.ly/4jTHfes

Please welcome our official #mesoSPIM channel on this platform, @mesospim.bsky.social. Repost is appreciated!

Fun fact: Alpacas love dust baths! 🦙💨

Spring at our farm means blossoms, sun & lots of happy rolling in the sand 🌸☀️
Just like our alpacas enjoy a refreshing dust bath, our clients enjoy smooth #sdAb discovery.

Let’s roll into new discoveries together 🙃!

#NanoTag #VHH #nanobody #AlpacaAntibodies

Very excited to present our latest work: SPINNA, an analysis framework and software package for single-protein resolution data! 🖥️🤩

We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨

🚀 New: sdAb anti-Human #IgG!
Expanding our #Smart Secondaries® (secondary #nanobodies) range with high-specificity sdAb clones for precise Human IgG detection. Minimized linkage error, superior penetration, ideal for one-step IF, ELISA, WB & therapeutic Ab testing. 👉 bit.ly/4ia1H9B

Synaptophysin accelerates synaptic vesicle fusion by expanding the membrane upon neurotransmitter loading Synaptophysin allows synaptic vesicles to expand during loading with neurotransmitters, resulting in faster fusion.

Finally a role for the most common synaptic marker in the world synaptophysin - maintaining synaptic vesicle diameter: www.science.org/doi/10.1126/...

Nanobinders for Synaptotagmin 1 enable the analysis of synaptic vesicle dynamics in rodent and human models. Synaptic neurotransmission is a critical hallmark of brain activity and one of the first processes to be affected in neural diseases. Monitoring this process, and in particular synaptic vesicle recycl...

Excited for our latest work! We developed nanobinders for the luminal domain of Synaptotagmin 1 (calcium sensor for synaptic vesicles). Thanks among others to @verstrekenlab.bsky.social @opazo.bsky.social @meunierlab.bsky.social @volkerhaucke-lab.bsky.social www.biorxiv.org/content/10.1...

Congrats Michelle!

Our lab at the NIH (Bethesda, MD) is looking for postdoctoral fellows to join our team studying the molecular mechanisms of protein trafficking and their links to neurodevelopmental disorders starting on or after 10-1-2025. Send your application to juan.bonifacino@nih.gov. Please share and repost!

I am very excited about the invitation of @petrikursula.bsky.social to give a seminar at the Uni Bergen (UiB) 🇳🇴. I’ll share some of our work using @nanotag.bsky.social engineered #nanobodies with erasable signals for multiplexing microscopy. Paper: lnkd.in/een2yCDx Seminar: lnkd.in/esNGXhiv

Same here!

Barrio Lastarria used to be one of my favorite going-out neighborhoods. great memories and wines in "El Berri", which does not exist any longer... Enjoy the conference!

We had a blast hosting curious young minds at NanoTag Biotechnologies for #Zukunftstag2025! From alpacas to #nanobodies, pipetting, microscopy, and liquid nitrogen fun❄️ 🌹with team from myriamed — science, teamwork, and discovery were in the spotlight! 🔬🧪🦙 #FutureDay2025 #ScienceIsFun #BiotechCareers

Interesting talks on the Extra Celular Matrix (ECM) session at the German Neuroscience Meeting here in #Göttingen #NWG2025; @neurowissg.bsky.social. Let's see what else is there interesting!

Hi Chris, very nice imaging. We are also trying similar staining on mouse cortex but have struggled to find the right primary antibodies. Could you share the targets you used here? Ideally will be if you can share the Abs you used 😉. Thanks!

An interesting preprint from the Horrocks' lab detailing the behavior of secondary nanobodies (such a @nanotag.bsky.social ones) at the single molecule level and optimizing protocols for multiplexed labeling: doi.org/10.1101/2025...

Sonoepigenetics: Spatiotemporal Calcium Dynamics and cAMP Signaling Driven by High Frequency Nanomechanostimulation Regulates Transient Epigenetic Modifications and Early Osteogenic Commitment in Mese... Cells effectively balance and integrate numerous pathways to adapt to external signals in an attempt to regain homeostasis, although the complex nuclear mechanotransduction mechanism through which thi...

I am Absolutely delighted to share the preprint of our last collaborative efforts where we investigated the impact of sonostimulation of Mesenchymal Stem Cells. Thread -1-

www.biorxiv.org/content/10.1...

#FluorescenceFriday News!
Super-resolution imaging gets a serious glow-up! ✨🌈
@nanotag.bsky.social & @abberior.rocks are bringing together the best of single-domain antibodies and cutting-edge fluorophores. Get ready to see your samples in a whole new light! 🦙+ 🍩 = #Nanobody + #STED

🔬 Two Göttingen innovators, @nanotag.bsky.social & abberior, team up to revolutionize super-resolution imaging! ✨🌈 By combining single-domain antibodies and advanced fluorophores, they’re set to transform how we see samples. 🍩🦙
#FluorescenceFriday #ComingSoon #Collaboration #Nanobody #STED

Explaining cutting-edge #immunofluorescence (IF) in 5 minutes? Challenge accepted!⏳😅
Join Dr. Steffen Frey at #TiM2025 as he pitches our #SmartSecondaries® properties, secondary #sdAb redefining #IF. nano-tag.com/technology/s...
Mar 19, 2025 |14:50 |Münsingen
#Microscopy #Nanobodies #Multiplexing

I am super happy to share our latest article entitled "Decoding the molecular interplay of CD20 and therapeutic antibodies with fast volumetric nanoscopy", now published in Science www.science.org/doi/10.1126/...
It was my postdoctoral work mit @sauer-lab.bsky.social Congrats to all the co-authors!