Stem Cell Podcast

Thank you for sharing! 🫶

Check out these liver #organoids from Dr. Takanori Takebe's lab!

Dr. Norikazu Saiki and the team produced organoids capable of forming their own internal blood vessels and coagulation factors.

Article: go.nature.com/44QbXPs
Discussion: bit.ly/3IGfUP1

This week: the #metabolomics of HSPCs!

A new @natcellbio.nature.com study from Drs. Marialena Lalioti, Mari Carmen Romero-Mulero, Joerg Buescher, and @ninacabezas.bsky.social identifies metabolic changes that occur with differentiation, aging, and #AML.

📝- go.nature.com/4kOZVLX
🎧- bit.ly/3IGfUP1

The other, other best part of meetings is sharing the science and fun with the next generation!

Great representation from Sharma lab at #BCVS25. Thanks Maedeh, Jemima, and Sean for excellent posters on all things iPSCs, organoids, organ chips, and cardiotoxicity! 🫀

🐌💫 Snail embryos never looked so fabulous!
Tubulin (white), phospho-histone H3 (pink), and F-Actin (cyan) light up this early stage like a cytoskeletal disco ball.
Image from Clemens Cabernard & Adam von Barnau Sythoff 🪩🧬 #FluorescenceFriday

Drs. @simonmiao26.bsky.social, Nicole Pek, and Drs. Minzhe Guo and @mingxiagu.bsky.social's labs co-differentiated mesoderm and endoderm in the same spheroid to vascularize lung and intestinal #organoids!

@cellpress.bsky.social article: bit.ly/3H1ar4V

Discussion: bit.ly/3IGfUP1

Drs. @kylessmith.bsky.social, Yiran Li, and a team in @doctorpauln77.bsky.social's lab at @sjcenos.bsky.social analyzed previously published #scRNAseq data and found no evidence of transitional cerebellar progenitors.

Read the article: go.nature.com/46iVgyl
Listen to the discussion: bit.ly/3IGfUP1

🥳 We just released our 300th episode!

Thank you to all of our listeners, whether you've joined us recently or been here since the beginning.

Stream the 300th episode here, featuring special guest Dr. Jeanne Loring (@jfloring.bsky.social): bit.ly/44YrzjU

Our 300th episode just dropped! 🎉

🦏 Listen to stem cell legend Dr. Jeanne Loring (@jfloring.bsky.social) discuss her wide-ranging work, from endangered species preservation to #CellTherapy for Parkinson's. 🧠

📍 bit.ly/3IGfUP1

New from the ‪@meleromartinlab.bsky.social & Dr. Kai Wang's lab!

Dr. Liyan Gong & her colleagues generated functional vascular #organoids via orthogonal activation of the transcription factors ETV2 and NKX3.1.

@cp-cellstemcell.bsky.social paper: bit.ly/3HH9Hlx
Episode: bit.ly/4nzLrCp

Our latest work is out today in @science.org: a self-organizing system that models organizer-driven patterning and commissural axon guidance in human neural development.

Work led by Massimo Onesto with Neal Amin in the lab

Introducing digital embryos!

Researchers at Southeast University Nanjing reconstructed full digital embryos at #SingleCell resolution during early #organogenesis.

📑 @cellcellpress.bsky.social: bit.ly/44EzzX0
🎧: bit.ly/4nzLrCp

My postdoc work at Treutlein lab and @graycamplab.bsky.social with @jasperjanssens.bsky.social is out in @science.org ! We screen for neuron subtypes using pro-neural TFs + morphogen combinations + scRNA-seq and profiled over 700,000 cells in 480 conditions. www.science.org/doi/10.1126/...

Load up your playlist with these 5 recent episodes of the @stemcellpodcast.com. 🎧🧵

➡️ Ep. 299: “Spinal Cord Development” Featuring Dr. James Briscoe
➡️ Ep. 297: “Live at ISSCR 2025: Advancing Regenerative Medicine with CiPSCs” Featuring Drs. Hongkui Deng and Candice Liew

This patient-derived #organoid co-culture system models #LungCancer and reflects the #immunotherapy outcomes of corresponding patients!

🔖 @cp-cellstemcell.bsky.social: bit.ly/466pcO2
🎙️: bit.ly/4nzLrCp

Congratulations to Dr. @akanksha-jain.bsky.social, Gilles Gut, and the Treutlein Lab and @graycamplab.bsky.social on their work live imaging brain #organoid growth!

@nature.com article: go.nature.com/4la2yZh
Episode with discussion: bit.ly/4nzLrCp

We have a new episode out!

Tune in to hear Dr. @jamesbriscoe.bsky.social from @crick.ac.uk discuss his research on the developmental dynamics of the #SpinalCord, and his position as Editor-In-Chief of @dev-journal.bsky.social.

Listen now: bit.ly/4nzLrCp

Thank you for a great interview! 👏

Data-driven modeling of inter-organelle dynamic interactions throughout differentiation with multispectral and label free live imaging With funding from the Allen Distinguished Investigators program, these investigators hypothesize that complex and dynamic patterns of organelle connection and communication are distinctive across diff...

How do organelles change over the course of a stem cell’s life?

ADIs @cohenlaboratory.bsky.social, @assafzaritsky.bsky.social , and @mattersoflight.bsky.social are using ML and cell engineering to explore the #FrontierScience of stem cell differentiation.
alleninstitute.org/division/fro...

New Podcast Episode: Arun Sharma on Using Space to Accelerate Stem Cell and Cardiac Research "Between a Rocket & A Hard Space" sat down with biomedical researcher Arun Sharma to talk about stem cell research in space.

🛰️ @arunsharmaphd.bsky.social was just interviewed on the International Space Station National Laboratory's podcast!

Learn about his work sending cardiac stem cells to space, and how #microgravity can accelerate #biomanufacturing and #DrugDiscovery.

📍 Listen here: bit.ly/46hfAQw

Catch up with #ISSCR2025 delegates!

Our 'On the Ground' episode is out now, and features discussions with delegates about their impressions of the meeting and the most memorable research presented.

Listen now: bit.ly/45DFhL1

Targeted suppression of glioma by ultralow-dose x-ray–induced photodynamic therapy and gold-based nanoclusters in preclinical models Gold clustoluminogens suppress glioma by ultralow-dose x-ray–induced photodynamic therapy.

Honored and thrilled that my PhD work is selected as the Featured Image on Science Translational Medicine! We developed gold nanoclusters to cross the blood-brain barrier, accumulate in glioblastoma. science.org/doi/10.1126/...
#STM #Glioblastoma #Nanomedicine #Intravitalimaging

We have a special episode out for you now, recorded live at #ISSCR2025!

Drs. Hongkui Deng and Candice Liew share the story behind their groundbreaking study transplanting CiPSC-derived islets into a patient with #Type1Diabetes.

Listen now: bit.ly/4n9c54K

Check out these liver #assembloids from the @merihuchlab.bsky.social!

Drs. Anna Dowbaj and Aleksandra Sljukic generated mouse liver assembloids that model aspects of aspects of biliary liver fibrosis.

📝 go.nature.com/4e11KU9
🗨️ bit.ly/4kRfsMk

Drs. @oscarabilez.bsky.social, Huaxiao 'Adam' Yang, and a team in Dr. Joseph Wu's lab generated vascularized cardiac and hepatic #organoids!

Read the @science.org paper: bit.ly/3FBuHtr
Listen to the discussion: bit.ly/4kRfsMk

Looking for something to listen to on the way home from #ISSCR2025?

Our final daily episode is out! Catch up on the research presented on the final day of the meeting.

Listen now: bit.ly/407DHx8

Thank you to our attendees, speakers, sponsors, and exhibitors for making #ISSCR2025 a great success! We hope you will join us in Montréal in July 2026 for #ISSCR2026!

Thank you all for an incredible #ISSCR2025!

Safe travels home and we'll see you in Montreal! ✈️

Thank you to everyone who joined us for our "On the Ground" #ISSCR2025 episode!

Hear what they had to say when the episode airs on June 24th!

We're back with another #ISSCR2025 episode!

Daylon and Arun discuss research on ex utero embryo culture, long-term brain #organoids, and sponge regeneration! 🧽

Check it out: bit.ly/4416YL6