Open Postdoctoral position, faculty mentor Ruth Huttenhain | Office of Postdoctoral Affairs
My lab @stanfordmedicine.bsky.social is recruiting! We are looking for a postdoc at the interface of quantitative proteomics and G protein-coupled receptor (GPCR) biology:
postdocs.stanford.edu/prospective/...
#TeamMassSpec #Proteomics #GPCR #Postdoc
02.10.2025 18:27 — 👍 23 🔁 20 💬 0 📌 0
ER needs ATP for processes like protein quality control, but can't make its own. Here, how ATP is imported into the ER lumen and exchanged for ADP.
24.05.2025 04:56 — 👍 20 🔁 8 💬 1 📌 0
YouTube video by Amanpour and Company
Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏
youtu.be/8YhJM6zxYDw?...
24.05.2025 01:13 — 👍 239 🔁 102 💬 1 📌 1
Thrilled to share the structure of dimerised human PINK1 docked to an endogenous translocase array on the mitochondrial surface, composed of two TOM complexes, bridged by a VDAC2 dimer! Published today in Science www.science.org/doi/10.1126/...
@wehi-research.bsky.social @komanderlab.bsky.social
13.03.2025 19:19 — 👍 168 🔁 57 💬 9 📌 6
Pamela J. Bjorkman
Wolf Prize Laureate in Medicine 2025
The 2025 Wolf Prize Laureate in Medicine, Professor Pamela J. Bjorkman “For pioneering innovative strategies to overcome viral defenses through novel antibody-focused approaches” @caltech.edu wolffund.org.il/pamela-j-bjo... @bjorkman-lab.bsky.social
10.03.2025 19:38 — 👍 7 🔁 4 💬 0 📌 0
C-terminal amides mark proteins for degradation via SCF–FBXO31 - Nature
SCF–FBXO31 scans proteins for C-terminal amidation and marks them for subsequent proteasomal degradation.
scary but fascinating - cells have a degradation pathway that hunts down C-terminal scars (amides!) on damaged proteins. just wow. chemical biology plus CRISPR at its best. big congrats to all authors!
www.nature.com/articles/s41...
29.01.2025 17:57 — 👍 107 🔁 34 💬 1 📌 1
Nice highlighting of @taylor-mighell.bsky.social's GPCR pharmacochaperone preprint by @dereklowe.bsky.social @science.org www.biorxiv.org/content/10.1...
19.01.2025 14:05 — 👍 11 🔁 4 💬 0 📌 0
In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:
17.01.2025 18:43 — 👍 424 🔁 134 💬 7 📌 19
iAPEX: Improved APEX-based proximity labeling for subcellular proteomics using an enzymatic reaction cascade
Ascorbate peroxidase (APEX) is a versatile labeling enzyme used for live-cell proteomics at high spatial and temporal resolution. However, toxicity of its substrate hydrogen peroxide and background la...
Proud to share our work spear-headed by PhD student Tommy Sroka with major contributions by #xenopus expert Kerstin Feistel.
Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.
11.01.2025 19:51 — 👍 34 🔁 16 💬 1 📌 1
Protein quality control is a tug-of-war between degradation machinery and chaperones that promote folding. Thrilled to see our latest manuscript is now published!
👇 Follow 🧵 for quick summary
journals.biologists.com/jcs/article-...
10.01.2025 17:10 — 👍 38 🔁 15 💬 1 📌 2
I am excited to report the preprint of my postdoc work in the @olzmannlab.bsky.social! We have discovered the first lipid droplet quality control pathway with broad implications for lipid physiology and diseases associated with LD accumulation and oxidative stress! #lipidtime
shorturl.at/2HqFd
08.01.2025 13:46 — 👍 64 🔁 15 💬 6 📌 0
Check out our work, where we discover how receptor GPCR senses pH! We solved a longstanding question by developing foundational GPCR DMS tech dev + structural bio! Led by brilliant PhD student @matthewkhoward.bsky.social and Nick Hoppe w/ @amanglik.bsky.social!
www.cell.com/cell/fulltex...
06.01.2025 23:47 — 👍 63 🔁 12 💬 3 📌 1
Interested in #organelle biogenesis, subcellular #membrane #protein targeting or #LipidMetabolism? We are hiring! #PhD student or #postdoc.
We combine #Biochemistry & #CellBiology with Computational Modeling & Experimental Physics / Physical Chemistry approaches.
#research #academicsky #AcademicJob
26.11.2024 14:51 — 👍 38 🔁 16 💬 1 📌 0
I’ll have more to say about this later, but please have a look, and I hope the #TeamTomo community finds good uses for those 1829 Chlamy tomograms 🧪🧶🧬🌾🔬
29.12.2024 16:17 — 👍 65 🔁 22 💬 2 📌 2
Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology
www.biorxiv.org/content/10.1...
23.12.2024 17:49 — 👍 268 🔁 92 💬 6 📌 11
My lab @Stanford studies membrane protein insertion, assembly and quality control at the human ER membrane. We develop tiny genetically encodable antibodies from alpacas, called nanobodies, as tools to acutely manipulate intracellular biology. Join us as a postdoc! Apply here: bit.ly/_Postdocs
18.12.2024 00:37 — 👍 14 🔁 2 💬 0 📌 0
Görlich lab develops secondary #nanobodies! They outperform conventional secondary antibodies and can replace these and their controversial production in animals: Nanobodies can be produced in large scale by bacteria. @JCellBiol http://www.mpibpc.mpg.de/15856308/pr_1726
20.12.2017 15:57 — 👍 1 🔁 1 💬 0 📌 0
Epigenetic Inheritance, Neuroscience & anything biology-related
https://www.odedrechavilab.com/
TED: https://shorturl.at/myFTY
Huberman Lab Podcast: https://youtu.be/CDUetQMKM6g
Assistant Professor at Stanford Biochemistry & Stanford Cancer Institute. We combine mass spectrometry, data science, and mechanistic biology to understand protein function and druggability. xiaolab.space
IMPRS_GS PhD student at MPI for Multidisciplinary Sciences
BIF PhD student in Schulman lab @mpibiochem.bsky.social, interested in structural biology and ubiquitin system
Evolutionary cell biology @EMBL
evonuclab.org
PhD student @ MPI-NAT | Dept. of Cellular Logistics - Görlich lab | nuclear pores, cargo transport, super-resolution, nanobodies ✨
IMPRS-ML student in Schulman lab, Max Planck Institute of Biochemistry🧪 BIF PhD Fellow 🔬 Interested in Ubiquitin, Protein Degradation and Molecular Signaling 👩🏻🔬
Postdoc @Komander lab, WEHI, Melbourne.
Mitochondrial biochemist interested in ubiquitin 🤓.
Mobilizing the fight for science and democracy, because Science is for everyone 🧪🌎
The hub for science activism!
Learn more ⬇️
http://linktr.ee/standupforscience
Therapist. Womanist. Speaker.
Multidisciplinary research at UMass Chan focused on membrane trafficking. Striving to make academic science a more diverse, equitable, welcoming and inclusive place. President of the American Society for Cell Biology (ASCB).
Opinions are mine
(she/her)
Amaro Lab (UC San Diego), PhD student Biochemistry and Molecular Biophysics | Computational Biology
Waitress turned Congresswoman for the Bronx and Queens. Grassroots elected, small-dollar supported. A better world is possible.
ocasiocortez.com
Medicinal chemist / chemical biologist, author of “In the Pipeline” at http://science.org/blogs/pipeline. derekb.lowe@gmail.com and on Signal at Dblowe.18
All opinions are mine; I don’t speak for my employer in any way.
Graduate student studying unconventional secretion and membrane repair in the Schekman Lab @ UC Berkeley MCB
Assistant Professor at the University of Minnesota Twin Cities | Biochemist & cell biologist / GPCRs | UCSF Postdoc, Caltech PhD | she/her
blythelab.umn.edu
Professor at Goethe University Frankfurt || proteostasis, mitochondria, autophagy, protein quality control, translation, infection, cancer, neurodegeneration || proteomics, molecular systems biology, cell biology || https://molsysmed.de
Immunologist x cell biologist x microbiologist at MRC LMB in Cambridge. Occasionally birdwatching. Less nerdy than my bio sounds. Views my own.
