Peter Bradley

First malaria medicine for newborn babies and young infants Coartem® (artemether-lumefantrine) Baby has become the first malaria treatment approved for newborn babies and young infants.

Huge News

Coartem® Baby—1st malaria drug approved for newborns <5 kg

It's a cherry-flavored mix of artemether (rapid parasite clearance) & lumefantrine (long-acting, prevents recrudescence)—dissolves in breast milk and optimized PK/PD for infant metabolism

Not-for-profit launch planned in Africa

Check out the gorgeous green eyes on this Shortfin Lionfish (Dendrochirus brachypterus)

You get extra karma points for rescuing and caring for JR!!!

Proteolytic processing and host nuclear targeting of the novel effector GRA84 in Toxoplasma gondii | Molecular Biology of the Cell Toxoplasma gondii and its relative Neospora caninum are apicomplexan pathogens that secrete an array of dense granule proteins into the parasitophorous vacuole and host cell, where they play roles in ...

www.molbiolcell.org/doi/10.1091/...

Nice work from my former graduate student Amara (now postdoc at Stanford) on a new effector protein in Toxoplasma www.molbiolcell.org/doi/epdf/10....

Make open access to tools and data part of your annual giving by making a tax deductible donation to @veupathdb.org. 💙This resource simplifies and supercharges global infectious disease research.

Need more reasons to support VEuPathDB? Here's a short list: veupathdb.org/veupathdb/ap...

"In California, solar generation could finally surpass gas this year."

Actually, the probability that solar surpasses gas in 2025 is high!

Gas fell from 50% of CA's electricity in January 2024 to 40% in January 2025, and solar rose from 20% to 28%.
www.canarymedia.com/articles/sol...
#energysky

bring back the cheddar jalapeño.......

Prediction:

Today (4/9/25) registered the greatest ill gotten gains from insider trading in history.

Vaccines. 💪🏻💪🏻

Great turn out for Stand up for Science rally in Westwood yesterday

Pro science crowd standing along Vetran Ave in Los Angeles

Stand Up For Science sign in Los Angeles with microscopes, plants, pipettes, 50ml tube and DNA drawn on it

Nice turnout and great weather at the Stand Up For Science rally in Los Angeles by UCLA

Protest at Space X in Hawthorne CA today. Seemed like 2-3k people showed up to me

Lots of crappy news out there recently - but at least my worms are happy....

we love helping the monarchs in CA - see some photos on my lab webpage.....

Monarch butterflies will get federal protections as a threatened species U.S. officials decided to extend protections to monarch butterflies after warnings from environmentalists that populations are shrinking and the beloved pollinator may not survive climate change.

www.npr.org/2024/12/10/n...

Amazing! ‘Twinkling Toxoplasma’ Tree (image by Kseniia Bondarenko) wins 2024 Festive Science Image Competition.

Like ‘old Twitter’: The scientific community finds a new home on Bluesky After recent changes to Elon Musk’s X, a gradual migration turns into a stampede

'For scientists the network is starting to look like home. Academic institutions, scientific journals and conferences, and international organizations such as the World Health Organization have established a presence there in recent days.'
www.science.org/content/arti...

Report: Every dollar of NIH research funding doubles in economic returns Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an

Research funded by NIH generated $2.46 in economic activity for every $1 of funding in 2023 [a total of $92.9 billion]

www.fiercebiotech.com/research/rep...

I would like to join

With Trump coming into power, the NIH is in the crosshairs The National Institutes of Health, the crown jewel of biomedical research in the U.S., could face big changes under the new Trump administration, some fueled by pandemic-era criticisms of the agency.

www.npr.org/2024/11/12/n...

Alveolin proteins in the Toxoplasma inner membrane complex form a highly interconnected structure that maintains parasite shape and replication Picomplexan parasites require specialized structures like the inner membrane complex to invade host cells and replicate. This study shows that the alveolin protein IMC6 is crucial for maintaining cell...

Congratulations to @petersmback.bsky.social on fantastic work on the Toxoplasma alveolin network and its interactions via UAA photocrosslinking. A really detailed study with great help from the Ward and Zhou labs! journals.plos.org/plosbiology/...

BCC0 collaborates with IMC32 and IMC43 to form the Toxoplasma gondii essential daughter bud assembly complex Author summary Toxoplasma gondii is an obligate intracellular parasite that causes severe and even fatal disease in congenitally infected neonates and the immunocompromised. The parasite replicates us...

Nice work out from my PhD student Rebecca on daughter cell assembly in Toxoplasma gondii journals.plos.org/plospathogen...

Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an essential regulator of Rab2 in the secretory pathway Toxoplasma gondii regulates vesicle trafficking by secreting Rab GTPases from specialised organelles. This study characterizes all Tre2-Bub2-Cdc16 (TBC) domain-containing proteins in T. gondii, identi...

Terrific work from my student Justin Quan (justinquan.bsky.social) on the TBC domain proteins in Toxoplasma gondii. journals.plos.org/plosbiology/...

Excellent work from my PhD student Rebecca was highlighted in The Scientist www.the-scientist.com/news/punctua...

Cat parasite Toxoplasma tricked to grow in a dish Cat-only life-cycle stage cultured in vitro, and the mysterious giant proteins that might turn bacteria into killers.

Cat parasite <i>Toxoplasma</i> tricked to grow in a dish

Identification of IMC43, a novel IMC protein that collaborates with IMC32 to form an essential daugh... Author summary Toxoplasma gondii is an obligate intracellular parasite that causes disease in immunocompromised individuals and congenitally infected neonates. Toxoplasma replicates using a unique pro...

Congrats to my PhD student Rebecca for very nice work on the essential daughter bud assembly protein IMC43 in T. gondii. journals.plos.org/plospathogen...