Nitin Kapadia

Network Motifs

From genes to patterns: five key dynamical systems concepts to decode developmental regulatory mechanisms Summary: Dynamical systems theory provides a powerful quantitative and intuitive framework to understand developmental processes. This Primer brings key concepts of this framework to the ever-growing ...

A Summer reading recommendation: new primer in @dev-journal.bsky.social explains how dynamical systems theory unlocks the logic of developmental patterning

Everything from bistable switches & oscillators to phase portraits & more with Python code to explore

journals.biologists.com/dev/article/...

YouTube video by MRC Laboratory of Molecular Biology Structure Prediction and Design using AlphaFold – Sami Chaaban

Great talk by @sami-c.bsky.social about the proper use and caveats of AlphaFold2/3 predictions, highly recommended to watch www.youtube.com/watch?v=z7vy...

📣 Applications now open 📣

We are seeking outstanding ECRs looking for a stimulating and supportive environment in which to establish their research group as externally-funded fellows, in any area or cell or molecular biology underlying disease!

Please share!

www.path.ox.ac.uk/work-with-us...

Head of the Cell Biology and Biophysics Unit The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organisation, and one of the world’s leading research institutions. An intergovernmental organisation of 29 Member S...

EMBL Cell Biology and Biophysics department is searching for a new director. A major position to lead this field in Europe and beyond.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Happy to be the next (and 1st female) @crg.eu director. The CRG always stood out to me, for its excellence in understanding life's principles, with implications for health and biodiversity, & its collaborative, open and innovative way of doing science. Thrilled to join its amazing community in 2026!

1 month to abstract deadline for the first cell biology of the nucleus meeting at @embl.org in many years - organised by the stellar @luskinglab.bsky.social @sarawickstrom.bsky.social Tom Quail & Simone Koehler

Tons of open slots, invited and selected speakers all get 20 mins ❤️

#EESNucleus

Postdoctoral Fellow - Costa Lab Salary for this Role: From £45,500 with benefits, subject to skills and experience. Job Title: Postdoctoral Fellow - Costa Lab Reports to: Alessandro Costa Closing Date: 03/Aug/2025 23.59 GMT Job Desc...

Less than two weeks left to apply!

Postdoc positions in my lab to study

1. initiation of DNA replication.

2. chromatin replication/epigenetic inheritance.

Great for biochemists, biophysicists & structural biologists.

Deadline 3 August 2025.

crick.wd3.myworkdayjobs.com/External/job...

CIG- UNIL

Become our colleague! Tenure-track Assistant Professor position at The Center for Integrative Genomics, University of Lausanne, Switzerland. unil.ch/cig/en/home....
More details for how to apply are here:
www.nature.com/naturecareer...

🚨Job alert in theory/math devbio 🚨
I’m currently advertising postdoc positions to join my group. We’re building reaction-diffusion models to understand some of the crazy things embryos can do. We are based in a beautiful part of Scotland :). Please share! www.abdnjobs.co.uk/vacancy/rese...

We are looking for new colleagues to come join us in Galway as group leaders (Junior and Senior). The Centre for Chromosome Biology is a great place and it is a good time to join. Please reach out if you want to chat about the opportunity!
www.nature.com/naturecareer...

Engineering yeast multicellular behaviors via synthetic adhesion and contact signaling By designing synthetic toolkits for contact-based signaling (MARS) and cell-cell adhesion (SATURN), we program yeast to form multicellular structures and perform complex tasks, like building logic cir...

Online now @ Cell is the yeast multicellular engineering paper from Fankang Meng - the fruits of his productive PhD in our group. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - specific adhesion, juxtacrine signalling and more. www.cell.com/cell/fulltex...

Human Development: Stem Cells, Models, Embryos. 7 - 9 September 2026 University of Warwick, UK. Resgiter your interest. #HumanDev26. Image credit: Susanna Narkilahti, Tampere University, Finland

Save the Date!

Development has teamed up with the Wellcome-funded consortium the Human Developmental Biology Initiative to co-organise a meeting on #HumanDevelopment.

📅7 - 9 Sep 2026
📍University of Warwick, UK

Register your interest for #HumanDev26: www.biologists.com/meetings/dev...

Control of CDK activity and the cell cycle by CKS proteins https://www.biorxiv.org/content/10.1101/2025.07.04.663185v1

Exciting Research Professorship Position in Stem Cell and Developmental Biology at the University of Leuven. Amazing research ecosystem, great colleagues, high quality of life, tenure track. For those interested in joining us, please see below:
www.kuleuven.be/personeel/jo...

UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

🔊 We are recruiting a postdoc to join us @crick.ac.uk and @ucl.ac.uk @ucl-ipls.bsky.social. Repost and help us spread the word and reach out if interested and have questions. Details and how to apply: www.ucl.ac.uk/work-at-ucl/...

First human genome from ancient Egypt sequenced from 4,800-year-old teeth Nature - Forty years after the first effort to extract mummy DNA, researchers have finally generated a full genome sequence from an ancient Egyptian.

Forty years after the first effort to extract mummy DNA, researchers have finally generated a full genome sequence from an ancient Egyptian

https://go.nature.com/44O0Sze

📣 We’re recruiting 1-2 Group Leaders! NCMBM is looking for early-career researchers ready to establish their independent research groups!

🧬 With an attractive start-up package, help us shape the future of molecular biosciences and medicine in 🇳🇴 and be part of the @nordicembl.bsky.social!

Researchers sequence first genome from ancient Egypt Researchers from the Francis Crick Institute and Liverpool John Moores University (LJMU) have extracted and sequenced the oldest Egyptian DNA to date from an individual who lived around 4,500 to 4,800...

Researchers from the Crick and @ljmuofficial.bsky.social have extracted and sequenced DNA from an individual who lived in Egypt around 4,500 years ago, making it the oldest genome from ancient Egypt sequenced to date.
www.crick.ac.uk/news/2025-07...

Who were the ancient Egyptians?

It is expressed in the extraordinary historical and archaeological record, but what about ancestry links to other ancient individuals?

Today we report the successful sequencing of the whole genome of an individual who lived in Egypt about ~4700 years ago.

Exciting news: our Board of Trustees has appointed @monicabettencourt.bsky.social as the CRG's new Director. Prof Bettencourt-Dias is expected to take up the post in 2026, replacing Dr. Luis Serrano, who will continue to maintain a research group at the institute.
www.crg.eu/en/news/moni...

Excited to share that our work building in vivo biosensors for receptor tyrosine kinases (pYtags!) is now out www.cell.com/cell-reports...

YouTube video by The Living Histories Series "Living Histories". James Ferrell | #TheLivingHistoriesSeries

A little interview with my postdoctoral advisor Jim Ferrell about his life. Timely as we prepare to celebrate his 70th birthday with a Ferrell -Lab-family symposium

youtu.be/ov9YMkmzUAg?...

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase - Nature Experiments in fission yeast show that cyclin-dependent kinase is first activated in the nucleus, from which the mitotic signal is propagated from CDK at the centrosome to the cytoplasm.

new out in Nature, the latest on the cell cycle in fission yeast, lovely basic biology www.nature.com/articles/s41...

The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells The DNA replication checkpoint prevents continued origin firing and fork collapse after replication fork stalling. Bertolin et al. show that excess Okazaki fragments from continued origin firing sequester replication processivity factors RFC and PCNA, leading to deprotection of DNA ends and fork collapse driven by the HLTF fork remodeler.

Online Now: The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells Online now:

The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks Canal et al. used biochemical reconstitution of DNA replication to show that continued Okazaki fragment synthesis after nucleotide exhaustion depletes PCNA, RFC, and DNA polymerases ε and δ, deprotecting replication forks and impairing restart. By limiting Okazaki fragment generation and factor depletion, the replication checkpoint protects forks, allows restart, and promotes survival.

Online Now: The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks Online now:

Call for 20 Assistant Professor positions Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.

ki.se/en/about-ki/...

Thank you Paul!

Thanks Luke!

Change of venue: fission-yeast cell-division cues actually initiate in the nucleus In yeast, the CDK and cyclin proteins that drive cell division activate first in the nucleus — a different location in the cell from where was previously thought.

In yeast, the CDK and cyclin proteins that drive cell division activate first in the nucleus — a different location in the cell from where was previously thought

https://go.nature.com/3GdXuEz