Pranav NM Shah's Avatar

Pranav NM Shah

@proteincapsid.bsky.social

Postdoc at STRUBI. Using cryo-EM to see viruses better.

422 Followers  |  215 Following  |  35 Posts  |  Joined: 04.10.2023  |  2.3005

Latest posts by proteincapsid.bsky.social on Bluesky

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ProteinCHAOS runs entirely in the browser and lets you choose how to visualize your protein structures.
It supports PDB files from the PDB and AlphaFold servers and offers several visual themes so you can "paint" abstract art with protein traces. I hope it helps you create some interesting images!

23.11.2025 23:18 β€” πŸ‘ 22    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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A particular highlight was to be able to see a bose-einstein condensate in Jorg Schmidmeyers lab at TU Wien.

24.11.2025 08:50 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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10 days and 4 Uni’s later, happy to be back in Oxford with a head full of ideas! Thanks once again @danielhurdiss.bsky.social, Panagiotis Kastritis, @schurlab.bsky.social and Pradyumna Paranjape for hosting me! Enjoyed discussing science with you and your colleagues and lab members!

24.11.2025 08:46 β€” πŸ‘ 10    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Spent my childhood in my G’Pa’s chem lab, loved birds then photography and the photography of viruses. Been capturing virus images since 2010 and across 3 continents.

23.11.2025 15:51 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Scientific journals: we don’t want you using generative AI because it makes shit up.

Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote

Same journal: AI cover art which makes no sense? Oooh!

23.11.2025 01:51 β€” πŸ‘ 193    πŸ” 42    πŸ’¬ 5    πŸ“Œ 2

Insightful!

21.11.2025 16:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
HMS - Postdoctoral Fellow in BCMP, Brown Lab We invite applicants for a postdoctoral fellow position in the Brown lab at Harvard Medical School in Boston, Massachusetts. The Brown lab uses structural, biophysical, and biochemical approaches to d...

Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526

18.11.2025 20:05 β€” πŸ‘ 19    πŸ” 19    πŸ’¬ 0    πŸ“Œ 1

Thank you for hosting me @danielhurdiss.bsky.social at @utrechtvirology.bsky.social! It was wonderful to visit and spend time with the members of the group. Until next time!

15.11.2025 07:37 β€” πŸ‘ 10    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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MPI-WIS postdoc application Max-Planck–Weizmann Postdoc (4-year, co-mentored) Together with Ori Avinoam (Weizmann), we’re recruiting a postdoc to uncover membrane remodelling mechanisms in muscle development using recombinant pr...

MPI–Weizmann Postdoc (4-year, co-mentored)
Together with Ori Avinoam (Weizmann), we’re recruiting a postdoc to uncover membrane remodelling mechanisms in muscle development using cryo-EM of recombinant proteins, and cell imaging/CLEM. Apply here by 21.11.25 forms.gle/ZtDWUjcTBu4d...

13.11.2025 16:31 β€” πŸ‘ 8    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0

Dont worry… clouds were very much in the way πŸ˜”

12.11.2025 17:19 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

"The result is a treadmill of constant activity with
limited progress whereas core scholarly practices – such as reading, reflecting and engaging with others’ contributions – is de-prioritized."
arxiv.org/pdf/2511.04820
Will the real scientists please stand up?

12.11.2025 12:34 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Whelp! Just saw this @builab.bsky.social ! Yes please give it a go and let me know if you have trouble using it.

11.11.2025 10:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Legendary place!

10.11.2025 19:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I'm pleased to announce 🍦 Icecream 🍨 v0.3!

New features include:
* Training on multiple tomograms (same training time, with linear increase in RAM) πŸš€
* Logging and plotting of the loss function πŸ“‰
* The --scale option is now called --eq-weight for clarity πŸ˜‰

We'd love to hear your feedback! πŸ™πŸ½

05.11.2025 14:41 β€” πŸ‘ 14    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1
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Our new preprint is out πŸ₯³πŸ₯³πŸ₯³

Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence?

πŸ‘‡

03.11.2025 12:26 β€” πŸ‘ 106    πŸ” 46    πŸ’¬ 3    πŸ“Œ 2

Congrats Ed!

03.11.2025 09:48 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

#RootingForRelion

30.10.2025 10:56 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Yes! I would very much like to go harder, faster, stronger! 😊😊😊

30.10.2025 10:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Jeremy is an excellent scientist and leader. Highly recommended!

29.10.2025 20:31 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

MRGA!

29.10.2025 23:51 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Vibe commit messgaes 🀣

29.10.2025 23:50 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Quick Check Needed

We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. πŸ€— RTs appreciated.

mrc.tal.net/vx/appcentre...

29.10.2025 09:17 β€” πŸ‘ 64    πŸ” 57    πŸ’¬ 2    πŸ“Œ 2
Dr Jeremy Keown Dr Jeremy Keown

warwick.ac.uk/fac/cross_fa...

I am advertising for a PhD position in my group. We'll be investigating how pathogenic RNA viruses replicate in the nucleus. The project will teach cryoEM/ET, virus culture, and in vitro assays.

If you're interested reach out and I'd be happy to have a chat.

24.10.2025 07:58 β€” πŸ‘ 13    πŸ” 18    πŸ’¬ 0    πŸ“Œ 1
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Structural and functional characterisation of the Crimean-Congo Haemorrhagic Fever Virus RNA Dependent RNA Polymerase Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is found across Africa, Asia, and the Middle East where it can cause Haemorrhagic outbreaks with high case fatality rates. Central to the viral life cycl...

www.biorxiv.org/content/10.1...

Really excited to have our work out in the world. CCHFV has a 450kDa L-Protein, about twice the size of L-Proteins from other segmented RNA viruses. We have used cryoEM and functional assays to begin to understand it this massive multifunctional protein works.

22.10.2025 12:21 β€” πŸ‘ 30    πŸ” 11    πŸ’¬ 2    πŸ“Œ 1
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End-to-end protein design in the browser through evedesign. Generate and interactively explore designs in 2D/3D and export them as codon-optimized DNA. The underlying open source framework (released soon) is build to easily add new methods, more on that soon.
🌐 evedesign.bio

22.10.2025 14:30 β€” πŸ‘ 92    πŸ” 30    πŸ’¬ 2    πŸ“Œ 1

Good one @dunnschool.bsky.social !

17.10.2025 17:39 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Warptools has an inbuilt aretomo3 wrapper that you can use. If your plan is to use M, i recommend preprocessing the data with warptools. Pytom-match pick natively supports warptools xml files for on the fly filter calculation.

16.10.2025 21:04 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Neat!

23.09.2025 16:06 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Nice one Flo @schurlab.bsky.social !

22.09.2025 17:09 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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