Xenbase

Van Itallie et al. present a deep analysis of changes of ∼15,000 proteins and ∼11,500 phospho-sites at 11 developmental time points in Xenopus laevis embryos. Published in Developmental Biology. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

It is absolutely crazy to think we no longer need model organism research. - Carole Labonne www.sciencedirect.com/science/arti... #science #devbio #xenopus #frogs

Bresteau et al. report that apical size reduction via macropinocytosis serves as a malleable and less destructive form of tissue remodeling that can alleviate the need for cell loss. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

National Xenopus Resource on X: "https://t.co/q9x70xVVLs Please watch video and post a comment in support of use of animal models. They are seeking our input and if we don’t provide it then they will simply say well we didn’t hear anything" / X https://t.co/q9x70xVVLs Please watch video and post a comment in support of use of animal models. They are seeking our input and if we don’t provide it then they will simply say well we didn’t hear anything

x.com/XenopusNXR/s...

Cyborg tadpoles: Sheng et al. developed soft, thin, stretchable bioelectronic arrays that integrate seamlessly into developing embryos’ brains. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

A significant emphasis will be placed on undergraduates, trainees, and junior faculty, with opportunities for platform presentations, flash talks, posters, and roundtable discussions.
@socdevbio.bsky.social @xenbase.bsky.social @dshb-antibodies.bsky.social @devdynamics.bsky.social

Midwest SDB 2025

The Midwest Regional Society for Developmental Biologists meeting, Sept 19-21, 2025, will be at Cincinnati Children's Hospital, Cincinnati, Ohio www.midwestsdbincincy.org
Registration deadline 9/7/25; abstract deadlines 8/7/25 for talks, 8/22/25 for posters.

2025 Midwest Regional Meeting of the Society for Developmental Biology, Sept. 19-21: Registration and Abstract Submission now open! midwestsdbincincy.org #science #devbio #xenopus #frogs

IXB Young Investigator Award Xenbase: The Xenopus Model Organism Knowledgebase.

Reminder: Nominations for the IXB Young Investigator Award are due by June 20. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

Stickers for upcoming meetings. #science #devbio #xenopus #frogs

Edwards et al. discovered that endosomal trafficking, is essential for delivering key proteins to the correct locations during trachea and esophagus development. Published in Developmental Cell. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

Cincinnati Xenbase BBQ dinner outing last Friday at Webb's BBQ in Newport, KY. Thanks to Joe Webb!

www.facebook.com/webbsbbq

#science #devbio #xenopus #frogs

The Alliance Office Hours topic for June is Orthology and Paralogy in the Alliance Thursday, June 12 @ noon (EDT). The registration form for the webinar is below.
docs.google.com/forms/d/e/1F...
The Alliance Events calendar is:
www.alliancegenome.org/event-calendar
#science #devbio #xenopus #frogs

There is no replacement (yet) for animal models in medical research The NIH is “reducing animal use in research.” But there is no replacement for animal models.

Please read and share this opinion piece written by Carole LaBonne (our fellow Xenopus researcher) published in STAT in support for animal models in biomedical research. www.statnews.com/2025/05/19/a... #science #devbio #xenopus #frogs

Abstract submission for the 20th International Xenopus Conference in Portsmouth, UK is extended to 12pm UK time, June 9! xenopusresource.org/20th-interna... #science #devbio #xenopus #frogs

A journal cover photo for Journal of Cell Science, Volume 137 (21) Novermber 2024. It is depicting a healthy frog retina labelled using wheat germ agglutinin (magenta), which binds to the photoreceptor outer segments; anti-calbindin antibody (green), which marks cone inner segments and a subset of bipolar cells; and Hoechst 33342 (blue), which stains cell nuclei. It has the Company of Biologists logo on the bottom left.

I think I can announce it (it's on the website now), but I'm really excited to say that I got the journal cover for the November issue of JCS! The retina is so beautiful, and I'm so happy I get to share that.
doi.org/10.1242/jcs....

🐸 🧪 #neuroskyence #academicsky #sciart 🐡

The International Xenopus Board (IXB) Young Investigator Award recognizes an outstanding junior faculty member from any country making significant scientific achievements using Xenopus. Nominations due June 20, 2025. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

Dr. Dominique Alfandari seeks requests for producing Xenopus antibodies. Fill out the form in the link to make your suggestions. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

Congratulations to Ray Keller, PhD for his election to the National Academy of Sciences. www.xenbase.org/xenbase/doNe... #science #devbio #xenops #frogs

a group of fish are swimming in a tank with green algae ALT: a group of fish are swimming in a tank with green algae

Y'all be crazy!

Don't make us slap you with our clawed and webbed feet!

Hello fellow froggers! Just over a week until the deadline for the Nikon Small World microscopy competition. Submit your images and show off the power of Xenopus! enter.nikonsmallworld.com #science #devbio #nikon #microscopy #xenopus #frogs

McCluskey et al. publish in Nature Communications how expression of autism genes is enriched in migratory embryonic gut progenitors causing GI dismotility. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

Developmental biology research leads to fundamental discoveries for biomedical research.
1/12

Cell Reprogramming. Gurdon 1962. PMID: 13951335.

Oocyte image by Brandy Walker and Amaya Moss
Tadpole line drawing from @xenbase.bsky.social

@socdevbio.bsky.social @rrbehringer.bsky.social

20th International Xenopus Conference. Portsmouth, UK. August 17-21. Registration now open. Abstract submission deadline: May 23. xenopusresource.org/20th-interna... #science #devbio #xenopus #frogs

Jaeger et al. screened Adeno-associated viral tools (AAVs) in three different amphibian species brains identifying serotypes that transduce neurons. Published in Developmental Cell. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

YouTube video by Cold Spring Harbor Laboratory Frogs: A biologist’s best friend

Frogs: A biologists best friend
Get up close and personal with the exotic amphibian helping students in CSHL’s Xenopus course study how life begins and operates. Watch the video clip on YouTube!! #science #devbio #xenopus #frogs
www.youtube.com/watch?v=T6wu...

NEW TOOL on Xenbase Simple Synteny Search: 16,000 synteny maps! Each map shows the gene of interest at center (yellow) flanked by 5 up and 5 downstream genes.
bio1.xenbase.org/synteny/Xenb...
Test it out and tell us if you find any bugs: Xenbase@cchmc.org #science #devbio #xenoopus #frogs

Xenbase Home Xenbase: The Xenopus Model Organism Knowledgebase

Our certificate problems are now resolved regarding Chrome, Edge, or other Chromium-based browsers. www.xenbase.org #science #biology #devbio #xenopus #frogs

Coiled gut with neurons tiled throughout

Happy #FluorescenceFriday from this #Xenopus tadpole gut stained for acetylated tubulin (magenta) and calretinin (green). By @pieceofkate.bsky.social who has been studying the development of enteric neurons in frog! (Zeiss Zoom widefield scope with apotome)