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Jon Downie

@jmdownie.bsky.social

Senior GI fellow @MGH_GI. Graduate of @MGHMedicine and @UofUMedicine (MD/PhD). Studying GI diseases through the lens of ‘omics.

119 Followers  |  352 Following  |  2 Posts  |  Joined: 19.10.2023  |  1.5456

Latest posts by jmdownie.bsky.social on Bluesky

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Droplet vs Picowell: Considerations for Single-cell Transcriptomic Profiling of Human Colon Biopsies Cellular and molecular profiling of gastrointestinal disease, especially cancer, has primarily focused on transcriptional dysfunction within epithelial cells; however, profiling epithelial cells from ...

Excited to share our paper comparing two scRNA sequencing approaches to profile the colonic epithelium is now out as the inaugural “Technical Advance” article in @aga-cmgh.bsky.social! This new series highlights emerging methods in GI research. bit.ly/42vJ4qp #GI #science

11.04.2025 14:57 — 👍 3    🔁 1    💬 0    📌 0
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Novel metabolomic predictors of incident colorectal cancer in men and women AbstractBackground. Metabolomic profiles may influence colorectal cancer (CRC) development. Few studies have performed pre-diagnostic metabolome-wide analy

Hello #medsky! I’m a senior GI fellow and physician scientist at MGH. I utilize ‘omics to understand risk and mechanisms of digestive diseases, namely colorectal cancer and GI bleeding. I recently published a study on circulating metabolites associated w/ CRC incidence! tinyurl.com/Downie-jnci 🧪

15.11.2024 19:12 — 👍 9    🔁 0    💬 0    📌 0

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