Ghost of Sortition

Circulating mitochondrial and cellular damage markers in long COVID: Links to cognitive function, psychological distress, and inflammation - Molecular Psychiatry Molecular Psychiatry - Circulating mitochondrial and cellular damage markers in long COVID: Links to cognitive function, psychological distress, and inflammation

“Persistent mitochondrial inflexibility and mitochondrial damage may contribute to Post-Acute Sequelae of COVID-19 (PASC).”

idp.nature.com/transit?redi...

Heat map and PMC estimates, 1 in 55 infectious and 892,000 new daily infections for Jan 12. We expedited the report to release it two days early.

The size of the winter COVlD wave has been revised upward as post-holiday data come in.

We estimate 1 in 55 people in the U.S. are actively infectious.

🔥WV: 1 in 14
🔥IN: 1 in 15
🔥MI & OH: 1 in 21
🔥MO: 1 in 22
🔥CT: 1 in 24
🔥KS: 1 in 25
🔥MA & IL: 1 in 27

Quick 🧵 1/4

The COVID generation: the neurodevelopmental consequences of in-utero COVID-19 exposure In historical viral epidemics, such as the H1N1 influenza and Zika viruses, prenatal exposures were correlated with risk for neuropsychiatric conditio…

“Overall, 14 % of toddlers in the pre-pandemic group were at high risk for developmental delays on the BSID-III compared with 51.6 % in the SARS-CoV-2 exposed group (p < 0.01; Table 1), unadjusted for covariates.”

www.sciencedirect.com/science/arti...

Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study Diverse neurological symptoms are experienced by long COVID and COVID-19 recovered individuals. However, the long-term effects of SARS-CoV-2 in the br…

www.sciencedirect.com/science/arti...

“These novel findings suggest that COVID-19 may lead to lasting brain alterations that potentially impact overall brain function even after recovery.”

I sometimes wonder how much this is impacting what we are seeing in the world.

idp.nature.com/transit?redi...

Why scientists are rethinking the immune effects of SARS-CoV-2 “Immunity debt,” a theory to explain the global surge in non-covid infections since pandemic restrictions were lifted, is increasingly being challenged by emerging evidence. Nick Tsergas reports Myco...

www.bmj.com/content/390/...

Persistent Attenuation of Lymphocyte Subsets After Mass SARS-CoV-2 Infection Growing evidence suggests that lymphocyte subsets are declined in COVID-19 patients, but it is unclear if these alterations persist after widespread e…

Here's the link without the ":5037" portion of the URL (dunno why Science Direct is including this unusual port # in their URLs):
www.sciencedirect.com/science/arti...

Read this twice.

“Our findings redefine SARS-CoV-2 infection as a condition of long-lasting immune compromise.”

www.sciencedirect.com:5037/science/arti...

This is figure 3, which shows distinct proteomic signatures of Cog-PASC in the exploration cohort.

The findings of a study in Nature Communications suggest distinct neurodegenerative processes in long COVID with cognitive impairment not seen in other long COVID subtypes, even after mild COVID-19 infection. go.nature.com/3MdTwyp #medsky 🧪

COVID-19 is “Airborne AIDS”: provocative oversimplification, emerging science, or something in between? COVID-19 caused by SARS-CoV-2 is often compared to other pandemics for its societal and global health impact, with some commentators drawing parallels to HIV/AIDS due to the immune dysfunction caused ...

Our new review article examines the parallels between COVID and AIDS, including the social impacts

www.ajpmfocus.org/article/S277...

To say people make a rational assessment of the threat environment around Covid… is just not true.

Most people refuse to talk about or read anything about Covid.

Long Covid has surpassed asthma as the most common childhood illness, and it’s rarely spoken of.

jamanetwork.com/journals/jam...

The double-edged sword: How SARS-CoV-2 might fuel lung cancer: Investigating the potential oncogenic mechanisms of the novel coronavirus in lung carcinogenesis The COVID-19 pandemic, caused by SARS-CoV-2, has had far-reaching consequences beyond acute respiratory illness, with growing evidence suggesting pote…

www.sciencedirect.com/science/arti...

Children and teens who had a Covid reinfection had a doubling of #LongCovid risk (PASC) and a significant increase in many other adverse outcomes (Figure) www.thelancet.com/journals/lan...

A new preprint study shows that the SARS-CoV-2 protein ORF6 directly kills human neurons. Not by accident, but through necroptosis - a kind of cell death where neurons burst and fuel inflammation. This may underlie the long-term brain symptoms of Long COVID.🧵

🚨🧵 by Zdenek Vrozina on Covid's impact on human neurons:

"A new preprint study shows that the SARS-CoV-2 protein ORF6 directly kills human neurons.
Not by accident, but through necroptosis - a kind of cell death where neurons burst and fuel..."

Full thread:
threadreaderapp.com/thread/19656...

Blueskyism

Why scientists are rethinking the immune effects of SARS-CoV-2 “Immunity debt,” a theory to explain the global surge in non-covid infections since pandemic restrictions were lifted, is increasingly being challenged by emerging evidence. Nick Tsergas reports Myco...

Outstanding article on covid’s impact on our immunity. We need to confront this emerging truth and stop this harm to all humanity.

@nicktsergas.ca
@senatorpaulasimons.bsky.social
@senpatrickbrazeau.bsky.social
@jmeddings.bsky.social
@snyderinstitute.bsky.social

www.bmj.com/content/390/...

Safety of JN.1-Updated mRNA COVID-19 Vaccines This cohort study investigates the association between booster vaccinations containing the JN.1 lineage and 29 serious adverse events in Denmark.

Impressive safety data for the JN.1 Covid booster vaccine from a nationwide Denmark study
jamanetwork.com/journals/jam...

YouTube video by Sabbath Worship in HD (Master Noise 60fps) Black Sabbath - War Pigs (Pop Shop 1970) (4K 60fps)

This is just a drum clinic. Absolutely unreal work here by Ward.

youtu.be/6BPIL8oNazk?...

YouTube video by Ozzy Osbourne - Topic Revelation (Mother Earth)

As far as Ozzy’s solo stuff, Revelation (Mother Earth) is my favorite.

youtu.be/meCb_LfzRhE?...

Seriously

That’s amazing.

YouTube video by RHINO Black Sabbath - Changes

🥲
youtu.be/dOz_dLmpT9A?...

Sabotage doesn’t get the credit it deserves. The Writ is so good.

The other interesting thing here is how decoupled WW and Walgreens data have become.

Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing - Scientific Reports Scientific Reports - Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing

“These findings were observed in patients who experienced mild acute COVID-19 that did not require hospitalization or ventilatory support.”

www.nature.com/articles/s41...

📌

@atranscendedman tweet: “Egyptian researchers analyzed data from over 4 million people and found that nearly 1 in 3 COVID-19 survivors face long-term cognitive or memory problems, while 43% experience persistent fatigue, revealing a major mental health burden from long COVID.” Long-term neurological and cognitive impact of COVID-19: a... bmcneurol.biomedcentral.com 2025-06-14 0 8.9K Views

New study with a very large sample size & with high rates of bad health outcomes. #COVID

Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology Background Neuropsychiatric symptoms emerged early in the COVID-19 pandemic as a key feature of the virus, with research confirming a range of neuropsychiatric manifestations linked to acute SARS-CoV-...

Oof…

“The prevalence rates for the different symptoms were as follows: fatigue 43.3%, memory disorders 27.8%, cognitive impairment 27.1%, sleep disorders 24.4%, concentration impairment 23.8%…”

bmcneurol.biomedcentral.com/articles/10....

These poor kids.