Natura Myeku

This rapid action by the Prebys Foundation is the kind of thing I hope other regional philanthropies are doing. It isn't the entire solution by far but it is great to see them chipping in to help investigators in the San Diego academic science community.

www.prebysfdn.org/stories/blog...

Early proteasome downregulation and dysfunction drive proteostasis failure in Alzheimer’s disease Jiang et al. find that proteasome dysfunction occurs early in Alzheimer’s disease and worsens with disease progression, impairing the ability of neurons to

Check out our cool paper on proreasome’s state in early AD. academic.oup.com/brain/advanc...

@maxkozlov.bsky.social do you have any insight about Columbia University Medical Center. Since you are mentioning CU Morningside campus

As per the NIH POs in our session just now: Columbia University is having funding freeze lifted. Nice to hear some good news for a change!

Major development a Columbia.

Unclear what effect this will have or how many grants it may affect. And it will be important to learn what Columbia gave up to get this.

But a major development nonetheless.

🚨 After more than three months, Columbia University is no longer frozen out of NIH funds, per source.

Terminated grants will not (yet) be reinstated, but money should begin flowing otherwise, I'm told.

We have a new preprint from the lab. Proteasome gene downregulation before tau accumulation in AD brains

APOE ε4–associated heterogeneity of neuroimaging biomarkers across the Alzheimer's disease continuum INTRODUCTION While the role of apolipoprotein E (APOE) ε4 in Alzheimer's disease (AD) susceptibility has been studied extensively, much less is known about the differences in disease presentation in...

Happy to share a new paper from the lab, published in Alzheimer’s & Dementia: APOE4-associated heterogeneity in neuroimaging biomarkers across the Alzheimer’s disease continuum alz-journals.onlinelibrary.wiley.com/doi/full/10.... 1/7

Wow wow! Congrats!!

Me too