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@bazzinilab.bsky.social

127 Followers  |  90 Following  |  14 Posts  |  Joined: 02.01.2025  |  1.9187

Latest posts by bazzinilab.bsky.social on Bluesky

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It is always a great pleasure to discuss your science with the scientific community you love the most. This time the platform was provided by #MidwestSDB25 @Cincinnatichildren's. Thanks for this opportunity @bazzinilab.bsky.social @stowersinstitute.bsky.social .

26.09.2025 21:47 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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This #MicroscopyMonday shows #zebrafish oocytes at various growth stages maintaining a delicate balance of lipid metabolism. The different color shades in this image represent distinct levels of lipid content throughout oocyte growth & maturation. @bazzinilab.bsky.social

25.08.2025 15:04 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Great start of the #CABDseminars 2025/2026 with the talk of Miguel Rodriguez de los Santos!

Dr. Rodriguez gave an insight of the studies from his PhD and Postdoc work focused on rate diseases. He was invited by @crisprscan.bsky.social!

Thanks for coming Miguel!

26.08.2025 15:26 โ€” ๐Ÿ‘ 6    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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#StowersGrad predoc @michaydiez.bsky.social recently returned to his alma mater, @intechchascomus.bsky.social , to share his #research on the #evolution of ribosome heterogeneity in teleosts. ๐ŸŸ ๐Ÿงฌ #gradschool

12.08.2025 18:52 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐ŸŽ‰ Congrats to postdoc Horacio Martรญn Pallarรฉs on being named a 2025 @pewtrusts.org Latin American Fellow!

His work in the @bazzinilab.bsky.social (a 2010 PEW Fellow) investigates how #Zika & #dengue viruses hijack host cells.

Read about the fellowship and full circle moment: bit.ly/4mHWJTS

12.08.2025 15:47 โ€” ๐Ÿ‘ 26    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Scatterplot showing fitness effect of ~7000 synonymous mutations in yeast: read count at start vs log2 fold change. Most data points are not significant but 204 points are significant outliers, either advantageous or deleterious.

Scatterplot showing fitness effect of ~7000 synonymous mutations in yeast: read count at start vs log2 fold change. Most data points are not significant but 204 points are significant outliers, either advantageous or deleterious.

At the same time, we made thousands of synonymous mutations in endogenous yeast genes and measured their growth. We used careful statistics and controls. Only 3%, 204 of 6874, had a fitness effect! This goes against a controversial recent result that most synonymous mutations had fitness effects.

07.08.2025 08:29 โ€” ๐Ÿ‘ 80    ๐Ÿ” 29    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 2
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This beautiful #MicroscopyMonday is a developing #sealamprey embryo. The green & red fluorescent stripes mark specific segments of the developing hindbrain which are highly conserved with other vertebrates. ๐Ÿ”ฌ(Krumlauf Lab)

11.08.2025 19:00 โ€” ๐Ÿ‘ 9    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Great to see #StowersGrad predoc Paco Guerra Garcia sharing his #science at the Molecular Genetics of Bacteria and Phages Meeting! ๐Ÿงช๐Ÿงซ #gradschool

11.08.2025 19:48 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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๐Ÿ‘ Congratulations to Gerton Lab member, Tamara Potapova for being a recipient of the NIH competitive R50 Research Specialist Award! Her work on centromeres could reveal new insights into #cancer and reproductive #aging.

๐Ÿ”— bit.ly/41DmDzP

11.08.2025 23:03 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Huge congratulation to Dr. Gabe! Gabriel da Silva Pescador on an amazing PhD defense!! It was a pleasure to be part of it!! @stowersinstitute.bsky.social @stowersgrad.bsky.social

05.08.2025 23:08 โ€” ๐Ÿ‘ 9    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Please join us in congratulating Gabriel da Silva Pescador, predoc in the @bazzinilab.bsky.social, on successfully defending his thesis today! Great job. ๐Ÿ‘ #PhD #GradSchool

05.08.2025 20:51 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Transitions in development โ€“ an interview with Jeffrey Farrell

@jeffreyafarrell.bsky.social talks about becoming a group leader, his insights on advocacy for developmental biology and his belief in unifying single-cell biology with classical approaches.

journals.biologists.com/dev/article/...

28.07.2025 16:06 โ€” ๐Ÿ‘ 60    ๐Ÿ” 19    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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It was a great pleasure to present my work at 19 th International Zebrafish conference, Madison, Wisconsin. #IZFC25 . Thank you @bazzinilab.bsky.social and @stowersinstitute.bsky.social for all the support.

12.07.2025 05:14 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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#DBfeature

Maternal and zygotic contributions to H3K4me1 chromatin marking during germ layer formation

by Kitt Paraiso, Ira Blitz, Ken Cho
www.sciencedirect.com/science/arti...

24.06.2025 12:41 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Joaquรญn delivering a mental award lecture.

Joaquรญn delivering a mental award lecture.

Terrific rallying cry of an @socdevbio.bsky.social award lecture from @mads100tist.bsky.social at #icdb2025! Our work and community are important, #DevBio matters, and itโ€™s up to us to tell everyone why. Donโ€™t give the enshittifiers an inch!

22.06.2025 18:30 โ€” ๐Ÿ‘ 46    ๐Ÿ” 10    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
A plate made out of wood, with de society for dev bio logo, 2025 Trainee Science Communication Award, my name, and "In recognition of extraordinary science communication and outreach efforts as a trainee member of the Society"

A plate made out of wood, with de society for dev bio logo, 2025 Trainee Science Communication Award, my name, and "In recognition of extraordinary science communication and outreach efforts as a trainee member of the Society"

Extremely honored to receive this prize from @socdevbio.bsky.social, which recognizes not only my love for developmental biology, but the extremely online I am ๐Ÿงช (protect science, protect people, viva la dev bio!)

22.06.2025 20:01 โ€” ๐Ÿ‘ 528    ๐Ÿ” 37    ๐Ÿ’ฌ 85    ๐Ÿ“Œ 13
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#Argonautes2025 - argonautes.img.cas.cz
Join us in Prague 27-30/8/2025 for the next edition of the Argonaute meeting #miRNA #siRNA #piRNA & #PIWI

Abstract submission for talk selection deadline is 30/6!

Please, spread the word @rnasociety.bsky.social @rti-umasschan.bsky.social

18.06.2025 11:46 โ€” ๐Ÿ‘ 16    ๐Ÿ” 13    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3
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Road to Research: Q&A with Vignesh Babu, Scientist in Custom Proteinโ€ฆ "Working at the Stowers Institute has provided me with a wealth of new knowledge about the diverse array of research organisms and the fascinatingโ€ฆ

Meet Vignesh Babu, Scientist in Custom Protein Resources in this #RoadToResearch Q&A!

"Working at the Stowers Institute has provided me with a wealth of new knowledge about the diverse array of research organisms and the fascinating proteins they possess."

Read more: bit.ly/40eqRNA

20.06.2025 12:25 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A picture of a poster session in a room. The session is full of people talking to each other and interacting in front of posters

A picture of a poster session in a room. The session is full of people talking to each other and interacting in front of posters

Developmental Biology is alive and well #2025ICDB๐Ÿงช

19.06.2025 19:09 โ€” ๐Ÿ‘ 63    ๐Ÿ” 3    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
Graphic depicting in vivo generation of CAR T cells

Graphic depicting in vivo generation of CAR T cells

In Science, researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells.

Learn more: scim.ag/4jVfcuk
#SciencePerspective: scim.ag/3STvdWC

19.06.2025 19:56 โ€” ๐Ÿ‘ 71    ๐Ÿ” 18    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

Gamechanger๐Ÿ‘‡๐Ÿป

19.06.2025 19:58 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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KI to recruit junior researchers with a focus on excellence On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility. As one of the worldโ€™s leading medical universities, KI o...

Please keep an eye open on the upcoming Junior PI recruitment at Karolinska. Come an join us in Stockholm. news.ki.se/ki-to-recrui...

19.06.2025 11:20 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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I will be presenting my work at International congress of Developmental Biology at Puerto Rico,if you are attending this conference and around, please do visit #ICDB25.

19.06.2025 11:52 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A picture of a projected slide with sponsors. Three people stand in front of the projected slide

A picture of a projected slide with sponsors. Three people stand in front of the projected slide

The #ICDB2025 begins! @labonnelab.bsky.social kicks off the festivities and reminds us how important it is to support Developmentaรฑ Biology ๐Ÿงช

18.06.2025 20:36 โ€” ๐Ÿ‘ 14    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Joaquin Navajas Acedo @mads100tist.bsky.social will receive the SDB Trainee Science Communication Award #ICDB2025 for his role in promoting Developmental Biology and Zebrafish in social media ๐ŸŸ๐Ÿงช

17.06.2025 14:42 โ€” ๐Ÿ‘ 63    ๐Ÿ” 6    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 2

#TCTeAC ... what's more than organizing one conference? Two conferences! This one is more Day Science on biology of Argonaute proteins from prokaryotes to Metazoa. Great line up of invited speakers. Some special fun included!

18.06.2025 12:09 โ€” ๐Ÿ‘ 19    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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NEW RESEARCH: Humans & fungi are genetically similar, making it tricky to target fungus without harming our cells. A study from the Zanders Lab & University of Georgia researchers found dozens of genes unique to most pathogenic fungi, w/ potential to develop new antifungal therapies.

bit.ly/3FL9LQu

06.06.2025 16:25 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Hear moreโฌ‡๏ธ #ResearchSky #SciSky

06.06.2025 16:29 โ€” ๐Ÿ‘ 6    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Figure taken from MacRae & Peterson (2015): How suitable are zebrafish for discovering human drugs? Although zebrafish enable in vivo studies on a large scale, questions remain about how relevant the findings are for drug discovery. Recent studies have begun to elucidate the degree of conservation between humans and zebrafish, which share 82% of disease-associated targets and a large number of drug metabolism pathways (as illustrated by the mass spectrometry of metabolic by-products). Zebrafish physiology is often well conserved (sometimes more so than rodent physiology); for example, cardiac electrophysiology (illustrative electrocardiogram (ECG) tracings from each organism are shown). Several compounds discovered in zebrafish screens have been shown to exhibit similar effects in rodent models and humans, including eight out of ten compounds tested by our groups. m/z, mass to charge ratio.

Figure taken from MacRae & Peterson (2015): How suitable are zebrafish for discovering human drugs? Although zebrafish enable in vivo studies on a large scale, questions remain about how relevant the findings are for drug discovery. Recent studies have begun to elucidate the degree of conservation between humans and zebrafish, which share 82% of disease-associated targets and a large number of drug metabolism pathways (as illustrated by the mass spectrometry of metabolic by-products). Zebrafish physiology is often well conserved (sometimes more so than rodent physiology); for example, cardiac electrophysiology (illustrative electrocardiogram (ECG) tracings from each organism are shown). Several compounds discovered in zebrafish screens have been shown to exhibit similar effects in rodent models and humans, including eight out of ten compounds tested by our groups. m/z, mass to charge ratio.

Due to their aquatic environment, #zebrafish are perfect for small molecule drug screens. Many drugs have been repurposed for novel treatments such as COX inhibitors in leukemia & glucocorticoids in long QT syndrome. For more, read this Nature review ($): doi.org/10.1038/nrd4... #ZebrafishFunFacts ๐Ÿงช

06.06.2025 14:40 โ€” ๐Ÿ‘ 18    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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