David Dufresne

Now, if hand shaking did that, I wouldn’t want to see what falling from his height - certainly a common occurrence at that age - lwould do to his brain…

Considering Trump’s usual diet, scurvy is not at all impossible. So is a whole list of hematological malignancies at his age.

I mean, bruising from minor trauma like hand shaking *is* possible.
It is very medically worrisome, but possible.
I had a teen with severe ID who bruised from her socks rubbing. She had scurvy…

Fanny how Elon is convinced that him having a baker’s dozen of kids is a way to improve the gene pool. Not self-aggrandizing at all…

It’s not the argument you think it is, as most educated people know someone that files rockets should know the plane is actually flying straight and this curve is just the result of distortions induced by our maps (search mercator projection).

SMH
Our department covers kids up to 400km away from our hospital. Virtual visits are an incredibly powerful tool for them. So thankfully I don’t have to deal with American healthcare (and politics) atm.

Subacute sclerosing panencephalitis - Wikipedia

Public service announcement: if your child recovers from measles, you’re not quite out of the woods:

en.m.wikipedia.org/wiki/Subacut...

Please get them vaccinated. It’s safe. It’s effective. And I’d really like to not have to tell parents their child will die a horrible death in a few months.

But the wildly racist content I’ve reported was deemed ok…
Please make 1984 a fiction again…

Great. Now I’m gonna have to start teaching med students about SSPE again…

You spelled "Dr Marino is entitled to be a competent, properly trained physician" wrong.

Also a potential targeted therapy for GRIN2A and ATP1A2 mutations based on overactive glutamatergic signaling (and maybe nonketotic hyperglycinemia down the road? Probably more centrally effective than the dextrometorphan that is widely used).

Randomized placebo-controlled crossover trial of memantine in children with epileptic encephalopathy - PubMed Memantine is an N-methyl-D-aspartate receptor antagonist, approved for dementia treatment. There is limited evidence of memantine showing benefit for paediatric neurodevelopmental phenotypes, but no r...

Who says it doesn’t?

pubmed.ncbi.nlm.nih.gov/36256600/

If that’s all one needs, then memantine is cheaper ;)

Gotta say - at least in peds Perampanel has a great tolerability profile, and the post-dose somnolence is a great side effect for those with initial insomnia or fragmented sleep.
Many of my families of neurodivergent kids swear by it because of that.

I guess the cremasteric and/or dartos? That’d leave you with a smooth, low riding scrotum…

Ouh, just in time for Superbowl…

Yeah, we tend to dislike Nazis.

No, we tend to love fair play. But don’t mess with us. We survive - thrive even eh - in -20 weather 4 months a year.
Heck, Canadian independence was achieved after our infantry’s conduct in WWI scared the Brits so much that they decided to give us our independence *before* we decided to ask for it.

Cover of a imaginary cookbook titled "How to cook like the people you just deported: Authentic ethnic flavors for bigots who don’t deserve them"

About to become very popular on Amazon

Ouh, it’d be delightful if we could cut power transmission across the border just as the game gets underway…

That’ll change once (I hope) once inflation reaches 5-10% again because of the trade war…

I’m usually against fossile fuels, but seems like that would be a good place for an oil well. "Drill baby drill" he says…

I don’t get the attraction anyway - between leaving the US and coming back to Canada in 2015 post fellowship and last December on conference in LA, Target changed so much. Prices have soared, everything is under lock - even socks! - good brands have dwindled in shelf space. Not a pleasant experience

Louder for people I the back. This is so. Much. Worse. Than anything I ever imagined. It’s not even just political, they even oppose the communication of plain science, tearing down the common truth we rely on to be able to understand one another.
Next step, full-on INGSOC.

(2/2)
c. At least two of:
- unilateral
- pulsatile
- moderate or severe
- worsened by/causing the avoidance of routine physical activity
d. At least one of:
- nausea and/or vomiting
- photophobia (worsened by strong light) AND sonophobia (worsened by strong sounds)

For the many med students out there that need a refresher in case they are questioned about migraine criteria, here they are:
a. 6+ episodes fulfilling criteria b-d
b. Headache 4-72h if untreated/unsuccessfully treated
(1/2)

I mean, miracle drugs could do it if you can resplenish telomeres. Just need to take care of the inevitable cancers that’d ensue. Now if only there was funding for cancer research…
Then take care of all age-related degeneration - brain, heart, kidneys, joints, etc, else you’ll just be sick longer.

Many excellent migraine and seizure trackers available - won’t be as functional, but one could conceive tracking their monthly migraines, their severity, etc. No need to have actual migraines.

And when someone black is accused of gun crimes, they’re confused as they can’t reconciliate this with their unconditional support for the 2A.

Please say you meant elemental lithium and not lithium salts, I’d love to see the result 🤣