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Michael Orger

@daniobrain.bsky.social

Neuroscience Group Leader at Champalimaud Centre for the Unknown. Zebrafish behavior and brain-wide imaging. Also some Danionella and Devario. Might post about music and Rubik's cubes.

685 Followers  |  517 Following  |  69 Posts  |  Joined: 04.08.2023  |  1.9865

Latest posts by daniobrain.bsky.social on Bluesky

Surf's Up
YouTube video by The Beach Boys - Topic Surf's Up

RIP Brian Wilson (1942-2025), one of the greatest innovators who helped build popular music into an enduring art form, and a kind and humble person. www.youtube.com/watch?v=S22a...

11.06.2025 19:13 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

It took us many years to improve idtracker.ai in both accuracy and tracking time. Here it is.

03.06.2025 14:46 โ€” ๐Ÿ‘ 16    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

I don't really understand why a table of contributions is bad. It seems like a straightforward way to give credit to people whose work contributed to the paper in different ways.

23.05.2025 12:32 โ€” ๐Ÿ‘ 7    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Mathematics in Biology Biology has turned into a quantitative science. The core problems in the life sciences today involve complex systems that require mathematical expression, ye...

If you're planning a course with mathematical methods content, or use such methods in your own work, please take a look at "Mathematics in Biology", by Meister, Lee, and Portugues, published at MIT Press. 1/2 @portugueslab.bsky.social mitpress.mit.edu/978026204940...

21.05.2025 21:53 โ€” ๐Ÿ‘ 60    ๐Ÿ” 16    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

Greatly deserved! Congratulations!

21.05.2025 10:53 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Unforgettable trip to Lisbon! Packed with amazing food, wine, science, art, sightseeing, and a healthy dose of exercise! Huge thanks to my hosts @ribeirocarlitos.bsky.social at Champalimaud and Razmik Panossian at the Gulbenkian Foundation for the warm welcome.

21.05.2025 07:32 โ€” ๐Ÿ‘ 48    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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Zebrafishology, study design guidelines for rigorous and reproducible data using zebrafish - Communications Biology A review emphasizes the advantages of using zebrafish in research, outlines key differences in experimental approaches, and offers guidelines for designing studies in a way that enhances experimental ...

A review emphasizes the advantages of using zebrafish in research, outlines key differences in experimental approaches, and offers guidelines for designing studies in a way that enhances experimental rigor and reproducibility. www.nature.com/articles/s42...

15.05.2025 19:06 โ€” ๐Ÿ‘ 10    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

Any album in particular?

16.05.2025 07:20 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Negativland - This Is Not Normal
YouTube video by NegativlandVideo Negativland - This Is Not Normal

www.youtube.com/watch?v=pUIG...

15.05.2025 23:34 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social ๐Ÿš€
github.com/danionella/w...

12.05.2025 05:25 โ€” ๐Ÿ‘ 194    ๐Ÿ” 54    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 3

High-resolution phenotypic screen in zebrafish identifies novel regulators of CNS axon diameter growth https://www.biorxiv.org/content/10.1101/2025.04.29.651302v1

01.05.2025 04:15 โ€” ๐Ÿ‘ 0    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

The latest paper from the Chiappe lab is out!! Congrats @merterginkaya.bsky.social and everyone involved - now you definitely have to come visit Lisbon so we can celebrate!๐Ÿฅณ @champalimaudr.bsky.social

01.05.2025 19:55 โ€” ๐Ÿ‘ 17    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Neural microexons modulate arousal states via cAMP signalling in zebrafish Arousal states, often dysregulated in neurodevelopmental disorders, shape how organisms perceive and respond to their environment. Here, we show that srrm3, a master regulator of neural microexons, is...

๐Ÿ  New pre-print from the lab! ๐Ÿ 

Neural microexons fine-tune protein function - but how do they impact arousal states and underlying neuronal signaling pathways?

www.biorxiv.org/content/10.1...

Check out our latest pre-print by @tahneema.bsky.social et al, @upf.edu @crg.eu. ๐Ÿงต๐Ÿ‘‡ 1/9

28.04.2025 09:24 โ€” ๐Ÿ‘ 36    ๐Ÿ” 15    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 4
MEGATON KICK '25 Clipใ€Kobaryoใ€‘
YouTube video by HARDCORE TANO*C MEGATON KICK '25 Clipใ€Kobaryoใ€‘

www.youtube.com/watch?v=CamI... This Kobaryo DJ set is all you need this weekend.

11.04.2025 16:47 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Am I the only person who keeps getting caught out by journals putting a 'download whole issue' button exactly where I expect 'download paper' to be

10.04.2025 11:02 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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It is hard to imagine a more prescient compilation than 1992's Artificial Intelligence, not just in terms of the careers of the contributing artists, but how the featured sounds have permeated popular culture over the last 30 years.

09.04.2025 13:46 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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I think the more rewarding goal would be to get closer to @andrewtanyongyi.bsky.social 's judgements than to the average.

08.04.2025 15:02 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

A beautifully curated resource for zebrafish research enabled by NIH funding.

03.04.2025 13:21 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

I've rewritten this 5 times now, but...
1) Charles Mingus
2) Wu Tang Clan
3) Bjork
4) Bob Dylan
5) Orbital
6) Nina Simone

31.03.2025 20:43 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I think itโ€™s a sort of penance that makes you feel ok about all the bacon and black pudding

28.03.2025 17:19 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Clinical assessment is the gold standard for autism diagnosis, and by using amply pre-trained language models paired with a suitable interpretability strategy, thenative analysis of clinical intuition itself is now possible, guided by detailed observational text reports from clinicians. This interpretable language model framework identified repetitive and stereotyped behaviors as being empirically more relevant for autism diagnosis than social signs in the reports, motivating the possible revision of existing diagnostic instruments.

Clinical assessment is the gold standard for autism diagnosis, and by using amply pre-trained language models paired with a suitable interpretability strategy, thenative analysis of clinical intuition itself is now possible, guided by detailed observational text reports from clinicians. This interpretable language model framework identified repetitive and stereotyped behaviors as being empirically more relevant for autism diagnosis than social signs in the reports, motivating the possible revision of existing diagnostic instruments.

Trained language model finds repetitive behaviors and special interests are more indicative of an autism diagnosis than a lack of social skills. https://www.cell.com/cell/fulltext/S0092-8674(25)00213-2

@mila-quebec.bsky.social @Danilo Bzdo

26.03.2025 15:00 โ€” ๐Ÿ‘ 6    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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Most decimal places of Pi recalled in one minute This record is for the most digits of Pi recalled in one minute. This record is to be attempted by an individual. This record is measured by the numbers of Pi recited in the timeframe. For the purpose...

Guinness WR is claiming a new record for the most digits of pi recalled in one minute at 280 (www.guinnessworldrecords.com/world-record...). Congratulations - however, it might need an update, as here is a video of Owen reciting 350: www.youtube.com/watch?v=ZL-j... @guinnessworldrecords.com

14.03.2025 23:46 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Post image 13.02.2025 14:52 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

For anyone concerned about the unlabeled horizontal axis, it should read 'Basic humanity (arbitrary units)'.

12.02.2025 16:34 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Chart showing amount of 2020 campaign materials devoted to disability rights. Sanders, Warren, Buttigieg and Klobuchar are far ahead of all candidates, with Trump and Biden at 0.

Chart showing amount of 2020 campaign materials devoted to disability rights. Sanders, Warren, Buttigieg and Klobuchar are far ahead of all candidates, with Trump and Biden at 0.

In light of the attack on protections for children with disabilities, I share this chart I made of the amount of attention given to this topic (which should be a winning one for any party) by 2020 presidential candidates.

12.02.2025 16:26 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

It is full of bizarre nonsense like this, that shows the compilers had no understanding of what they were reading. What an embarrassment!

12.02.2025 15:20 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I found almost immediately one which funds development of a light-sheet microscope for imaging brains. Why is this problematic to Ted Cruz? Because the authors say that by reducing costs for this technology the methods will become more accessible to a wider community.

12.02.2025 15:20 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Cruz-Led Investigation Uncovers $2 Billion in Woke DEI Grants at NSF, Releases Full Database

This database of 'woke' grants compiled by Ted Cruz is spectacularly dumb. www.commerce.senate.gov/2025/2/cruz-....

12.02.2025 15:20 โ€” ๐Ÿ‘ 8    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Coming soon: Fighting Fantasy - Solo Adventure Gamebooks - Back In Print! Five roleplaying adventures by Ian Livingstone and Steve Jackson. The classic series that's part story, part game - you are the hero!

www.kickstarter.com/projects/sjg...

11.02.2025 18:58 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Couldn't they have gone with Gulf of the United States?

11.02.2025 16:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@daniobrain is following 20 prominent accounts