International Parkinson and Movement Disorder Society®

Our COA Scientific Evaluation Committee analyzed outcomes for dozens of cognitive function tests to assess their validity, reliability, and sensitivity to change in the PD population. Only a handful achieved the study’s “Recommended” designation. https://loom.ly/8IRCO44

DBS is a promising treatment for various forms of dystonia, but long-term data is lacking. Drs. Andrea Kühn and Patricia Krause discuss the efficacy and safety results of the longest GPi-DBS follow-up study for generalized and segmental dystonia. https://loom.ly/yawREAw

What began as a bold idea—naming a clinic "Movement Disorders"—sparked a global revolution in neurology.

Join us at the #MDSCongress to honor the past, celebrate the progress, and shape the future of movement disorders. mdscongress.org

The significant global variation among genetic ataxias, as evident in the MDSGene database, illustrates the importance of identifying regional epidemiology to inform rational ataxia-specific genetic testing. https://loom.ly/rk2AN8I

Explore DBS, infusion therapies, and multidisciplinary approaches with global experts.

🔗 Register now: https://loom.ly/zChZck4

#Neurology #DBS #Parkinsons

Tip of the hat to two of the three co-founders of the MDS Aspen Movement Disorders Course. Two of the greatest of all time, David Marsden and Stan Fahn. It was a fabulous week; so fortunate to complete year 35 and to carry on this tradition for the next generation. @parkinsondotorg.bsky.social

The MDS Aspen Course is considered a "rite of passage" for movement disorders fellows.

This year’s Aspen Video Case Presentations, co-chaired by Dr. Alberto Espay and Dr. Anthony Lang, showcased the depth and complexity of real-world clinical practice.

International Congress of Parkinson's Disease and Movement Disorders®

Register before July 30 (midnight CDT) to receive the best rates. mdscongress.org

Thank you to the Parkinson’s Foundation for their generous support of the Fellows Luncheon during the “Comprehensive Review of Movement Disorders for the Clinical Practitioner” course in Aspen, Colorado. Fellows had the opportunity to connect with and gain valuable career insights from the faculty.

Today is the #MDSCongress early registration deadline. Register now to receive the best rates. mdscongress.org

Advancing Parkinson's disease research in Africa: A strategic training framework of the Global Parkinson's Genetics Program (GP2) GP2’s collaborative research, training, and capacity-building initiatives aim to address knowledge gap in the region.

Young researcher highlight: Analyzing challenges to GP2’s collaborative research, training, and capacity-building initiatives in Africa. https://loom.ly/Y6jNuLQ

Train with leading experts in botulinum toxin muscle selection and injection techniques. https://loom.ly/ymD5Fjw

Neurotrophic factors, like GDNF, have had promising preclinical results for PD. Dr. Amber Van Laar breaks down her study investigating the potential benefits of a viral vector-delivered GDNF gene therapy for moderate PD patients. https://loom.ly/a6AGoBE

Hands-on practice: Clinical examination, differential diagnoses, treatment skills, emerging therapies, and more. https://loom.ly/Y4iXvS4

Changes in action tremor in Parkinson's disease over time: Clinical and neuroimaging correlates Widespread diffuse brain atrophy may disrupt processes involved in tremor generation, thus reducing action tremor as PD progresses.

Young researcher highlight: Widespread diffuse brain atrophy may disrupt processes involved in tremor generation, thus reducing action tremor as PD progresses.
https://loom.ly/nJDW_3g

Present your work to leaders and colleagues across the region. Submit an abstract for presentation at the 6th #PASCongress. https://loom.ly/L8q9Iy0

Next-generation sequencing has advanced our understanding of epilepsy-dyskinesia syndromes, shifting diagnosis from symptom-based categories to those defined by shared genetic and pathophysiological mechanisms.

Call for Applications — Editors of the MDS journals
Apply for MDJ editor: https://loom.ly/lnxf_nc
Apply for MDCP editor: https://loom.ly/0L3tKZY

Human aging and brain cell degeneration go hand in hand due to prolonged protein aggregation. This #MDSCongress panel discussion will explain how neurobiological mechanisms inform key therapeutic strategies. Mdscongress.org

Movement Disorders Journal Symposium

Explore the latest in Parkinson’s disease research at the MDJ Symposium on November 14 in San Diego, CA, USA. A must-attend satellite event of #SfN2025. Register now: https://loom.ly/1CJxmpY

Call for: Photographs, letters, medical artifacts, books, and/or memorabilia that focus on Jean-Martin Charcot and the 19th century French neurological school for an exhibit at the 2025 International Congress in Honolulu.

Learn more and submit here: https://loom.ly/Q84HLyo

DBS presurgical evaluations often involve a multidisciplinary team, yet social workers are underutilized. Dr. Amanda Currie shares insights on the value of social workers in the DBS process and how other programs may benefit from these findings. https://loom.ly/zrklMHE

Clinical Clue from Dr. Abhimanyu Mahajan: Learn how to recognize mirror movements in early PD and how they may differ in corticobasal syndrome. @amahajanmd.bsky.social‬

Levodopa has been the “gold standard” therapy for PD, but in recent years, therapy options have increased rapidly. These options now include DBS, subcutaneous levodopa infusions, and various other pharmacological aids. Learn more: https://loom.ly/DsWX7_A

Mitochondrial DNA copy number as a potential biomarker for the severity of motor symptoms and prognosis in Parkinson's disease The number of mitochondrial DNA copies within blood cells, or mtDNA-CN, could also function as a diagnostic biomarker for PD.

Young researcher highlight: The number of mitochondrial DNA copies within blood cells, or mtDNA-CN, could also function as a diagnostic biomarker for PD. https://loom.ly/EOj0ZwA

A 4-hour online course covering common movement disorders, useful assessment scales and available treatment options. (Français + English)

En français: https://loom.ly/B1ror1A
In English: https://loom.ly/euyPTWg

Disrupted amygdala functional connectivity is mediated by the nucleus basalis of Meynert in Parkinson’s disease patients with hallucinations “Double hit” of interactions between multiple pathologically affected circuits may predispose individuals to hallucinating.

“Double hit” of interactions between multiple pathologically affected circuits may predispose individuals to hallucinating. https://loom.ly/8aXss_A

Cognition and Lewy Body Diseases Study Group

Join the new Cognition and Lewy Body Diseases Study Group to collaboratively study and advance research related to Lewy Body Diseases and Movement Disorders. Learn more: https://loom.ly/eiJ9MEE

Metabolic movement disorders can be complex and require neurological and laboratory assessments. Learn key diagnostic and clinical management tools. https://www.movementdisorders.org/Fundamentals

iNPH symptoms vary widely and often overlap with other diseases like AD and PD. To help improve diagnosis for iNPH, there needs to be better standardization within clinical descriptions and assessments. https://loom.ly/Bn61TPw