Aleksandra Skrajna's Avatar

Aleksandra Skrajna

@askrajna.bsky.social

Asst Prof at UC Santa Cruz, studying histones and chromatin, using CryoEM and proteomics. New mom. Dog lover. Athlete. University of Warsaw -> Polish Academy of Sciences -> UNC Chapel Hill -> UCSC

1,374 Followers  |  93 Following  |  18 Posts  |  Joined: 24.09.2023  |  1.7311

Latest posts by askrajna.bsky.social on Bluesky

Welp, i got halfway through the RPPR and then received notice the MOSAIC program, and thus my MOSAIC R00 has been terminated.

Thank you to those who made this program.

Thank you to the other #NIHMOSAIC fellows have supported me through my faculty journey and continue to inspire me.

02.04.2025 19:08 β€” πŸ‘ 95    πŸ” 20    πŸ’¬ 20    πŸ“Œ 3

John Mellnik, Jack Scannell: Tripartite models for estimating the value of drug candidates and decision tools https://arxiv.org/abs/2503.22117 https://arxiv.org/pdf/2503.22117 https://arxiv.org/html/2503.22117

31.03.2025 06:18 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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General Chemistry Assistant Teaching Professor (Initial Review Date: May 14, 2025) University of California, Santa Cruz is hiring. Apply now!

The Department of Chemistry and Biochemistry at UC Santa Cruz is looking for a General Chemistry Assistant Teaching Professor -
recruit.ucsc.edu/JPF01884
We truly value teaching and mentoring and looking for like minded applicants.
Please apply, share, and recommend people who might be interested.

29.03.2025 04:15 β€” πŸ‘ 6    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Guest Commentary | Trump is turning off the lights on biomedical research: Why it matters for Santa Cruz β€œThese cuts aren’t just about UCSC; they’re about Santa Cruz,” writes Needhi Bhalla, Susan Carpenter and Carol Greider in a Guest Commentary. β€œThis crucial NIH support fuels our l…

Opinion piece in the @scsentinel.bsky.social by me, @carpenterlab.bsky.social and Carol Greider: Trump is turning off the lights on biomedical research: Why it matters for Santa Cruz

www.santacruzsentinel.com/2025/03/20/g...

21.03.2025 15:22 β€” πŸ‘ 75    πŸ” 51    πŸ’¬ 2    πŸ“Œ 4
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APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons - Nature Communications The APC/C ubiquitylates histones to regulate gene expression in pluripotent cells. Here, the authors pair cryo-EM and biochemical and biophysical assays to show that instead of modifying nucleosome-in...

My most challenging postdoctoral project, where we show that histones but not nucleosomes are polyubiqutinated by the APC/C for a potential proteasomal degradation was just published in @naturecomms.bsky.social
πŸŽ‰
www.nature.com/articles/s41...

Big shout-out to all co-authors!!!

20.03.2025 16:35 β€” πŸ‘ 12    πŸ” 3    πŸ’¬ 0    πŸ“Œ 2
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UC Santa Cruz researcher Upasna Shrarma and team uncover four novel genes essential for male fertility in mice, contributing to her broader federally funded research on how a father’s life experiences & environment influence the health of his children.πŸ”¬πŸ‘¨β€πŸΌ #ScienceNews

news.ucsc.edu/2025/03/trna...

05.03.2025 18:25 β€” πŸ‘ 8    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1

Really nice infographic of the cost of federally sponsored research.
www.cogr.edu/sites/defaul...

11.03.2025 18:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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UC Santa Cruz professors and students rally for science Several hundred people rallied in Santa Cruz Friday to support science in the face of significant threats to federal funding. β€œStand Up for Science” rallies took place on the UC Santa Cruz main campus...

www.kazu.org/kazu-news/20...

08.03.2025 04:08 β€” πŸ‘ 13    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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JEDI Award - Life Science Editors Foundation Our Justice, Equity, Diversity and Inclusion (JEDI) awards provide Feedback on Your Scientific Writing from one of our expert volunteers. These awards are offered quarterly to scientists facing unfair...

JEDI awards provide input on a manuscript, short grant proposal, or job application to scientists facing unfair, systemic barriers to career progression. Next deadline March 10th - please share & apply! lifescienceeditors.org/apply/

04.02.2025 19:25 β€” πŸ‘ 9    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

Thank you!

10.12.2024 17:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

After an exciting year of setting up my lab and life in Santa Cruz I am back on bluesky and hope to interact with y'all more.
I'm gearing up towards setting up an arrayed CRISPR screen and wonder what are your favorite companies to work with for guide RNAs. Edit Co, IDT, Horizon?

09.12.2024 23:55 β€” πŸ‘ 14    πŸ” 2    πŸ’¬ 3    πŸ“Œ 1
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Elements of successful NIH grant applications | Proceedings of the National Academy of Sciences Is there a formula for a competitive NIH grant application? The Serenity Prayer may provide one: "Grant me the serenity to accept the things I cann...

Super useful and eminently readable demystification of writing a successful NIH grant application, written by NIH Program
Officers (POs) with LOTS of great guidance:

04.04.2024 15:10 β€” πŸ‘ 18    πŸ” 15    πŸ’¬ 1    πŸ“Œ 1

It's hard to be a new PI and new mom without a daycare (yet). Sending β™₯️ to all moms in academia.

14.02.2024 20:05 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Happy International Day of Women and Girls in Science!!!

11.02.2024 17:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Exciting news - my lab is hiring a junior scientist! Please apply if you are interested in learning lots of biochemistry and helping me run the lab.
recruit.ucsc.edu/JPF01676

25.01.2024 20:57 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Thank you for the highlight Cassandra!

12.01.2024 19:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Research Technician This position will be supporting the Med Admin- Research department and provide technical support for daily operations of the CryoEM Core. The CryoEM Core is a multi-user facility that provide researc...

Great job opportunity at UNC Chapel Hill for anyone who wants to learn or dive deeper into CryoEM. Josh (core director) is fun to work with and continues to develop new approaches and methods in CryoEM. Therefore this appointment is not just a routine technical work it's actually very creative!

29.11.2023 16:19 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I opened the eggnog season today. A little balm to my heart in these difficult times. Cheers.

14.11.2023 02:14 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Yesterday I received a Postdoctoral Award for Research Excellence πŸŽ‰ Having my friends and family in the audience was incredibly moving. What a year ?! 1) I got a dream job, 2) I had a baby and now 3) this award. I'm incredibly grateful for everyone who made it possible 😊

28.10.2023 19:06 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I'd also add that Alphafold doesn't predict interactions of nucleic acids with proteins, which are the basis of so many biological processes.

20.10.2023 16:01 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Nice news and views article covering our recent manuscript on bacterial histones. Thanks for covering this! www.nature.com/articles/s41...

19.10.2023 15:43 β€” πŸ‘ 15    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

I think I got it now.

20.10.2023 00:10 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I'm trying to add my profile photo, I save changes, but it turns black when I go back to home view. Any advice?

19.10.2023 21:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Post image 19.10.2023 19:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

UNC PARE ceremony is next Friday at 3PM (10/27/23) πŸŽ‰
research.unc.edu/2023/10/18/2...

19.10.2023 19:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

@askrajna is following 20 prominent accounts