Maggie Chasse, PhD's Avatar

Maggie Chasse, PhD

@maggiechasse.bsky.social

Zon lab NCI K00 postdoc | pediatric sarcoma PhD | Luger lab chromatin biochem MS | transcription and melanoma in #zebrafish 🐠 | she/her

1,036 Followers  |  665 Following  |  108 Posts  |  Joined: 08.10.2023  |  2.0514

Latest posts by maggiechasse.bsky.social on Bluesky

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The most wonderful group of scientists, and now friends, to organize a trainee focused meeting to kick off SMR 2025!

25.10.2025 15:22 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine

06.10.2025 11:21 β€” πŸ‘ 154    πŸ” 72    πŸ’¬ 2    πŸ“Œ 12

I was about to tag @nucleosomepolice.bsky.social but she beat me to it. πŸ˜‚πŸ˜‚

30.09.2025 21:27 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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One of my cats is very regal and one is very much not. This custom poorly drawn pet portrait perfectly captures their dichotomy πŸ˜‚πŸ˜‚

27.09.2025 20:00 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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My yearly PSA to vote Grazer, a true feminist icon. πŸ‘‘ @fatbearweek.bsky.social

24.09.2025 12:05 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We are hiring! The Wattrus lab at MGH is seeking talented postdoc applicants to join our group and study differences in regeneration and wound healing across species using fish models. We are a fun group - come and join us! Fishy friends, please spread the word! #zebrafish #medaka #zebrafishjobs

02.09.2025 16:00 β€” πŸ‘ 10    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Fragile Nucleosome Fall Seminars:
September 10    Grace Bower, Kvon Lab @ UC Irvine, USA
    Jennifer Phillips-Cremins, UPenn, USA

September 24    Ali Wilkening, Sanulli Lab @ Stanford, USA
    Juanma Schvartzman, Columbia University, USA

October 8    Sanim Rahman, Greenberg Lab @ UPenn, USA
    Alex Federation, Talus Bio, USA

October 22    Alice Laigle, Croll Lab @ University of NeuchΓ’tel, Switzerland
    Seungsoo Kim, UC Irvine, USA

November 5    Hannah Long, University of Edinburgh, UK
    Jeff Vierstra, Altius Institute, USA

November 19    Ishtiaque Hossain, Pastor Lab @ McGill, Canada
    Sarah Teichmann, University of Cambridge, UK

December 3    MarΓ­a Mariner FaulΓ­, Rada Iglesias Lab @ IBBTEC, Spain
    Jonathan Henninger, Carnegie Mellon, USA

December 17    Rebecca Berrens, Oxford University, UK
    Jean-Benoit Lalanne, University of Montreal, Canada

Fragile Nucleosome Fall Seminars: September 10 Grace Bower, Kvon Lab @ UC Irvine, USA Jennifer Phillips-Cremins, UPenn, USA September 24 Ali Wilkening, Sanulli Lab @ Stanford, USA Juanma Schvartzman, Columbia University, USA October 8 Sanim Rahman, Greenberg Lab @ UPenn, USA Alex Federation, Talus Bio, USA October 22 Alice Laigle, Croll Lab @ University of NeuchΓ’tel, Switzerland Seungsoo Kim, UC Irvine, USA November 5 Hannah Long, University of Edinburgh, UK Jeff Vierstra, Altius Institute, USA November 19 Ishtiaque Hossain, Pastor Lab @ McGill, Canada Sarah Teichmann, University of Cambridge, UK December 3 MarΓ­a Mariner FaulΓ­, Rada Iglesias Lab @ IBBTEC, Spain Jonathan Henninger, Carnegie Mellon, USA December 17 Rebecca Berrens, Oxford University, UK Jean-Benoit Lalanne, University of Montreal, Canada

We're super excited to announce the entire lineup for the Fall season of Fragile Nucleosome Seminars, starting on Sept 10th at 1200 EDT / 1600 UTC with @gracebower.bsky.social and @creminslab.bsky.social!

register here for the entire series: us06web.zoom.us/webinar/regi...

01.09.2025 14:59 β€” πŸ‘ 66    πŸ” 36    πŸ’¬ 0    πŸ“Œ 8
Mechanical confinement governs phenotypic plasticity in melanoma - Nature Mechanical confinement of cancer cells at the tumour–microenvironment interface induces phenotype switching through chromatin remodelling by HMGB2, leading to a more invasive and drug-resistant state ...

My recent postdoctoral work is out today in @nature.com! We found that physical confinement makes melanoma cells more invasive and drug tolerant. Thanks to all who made this work possible @whitefishlab.bsky.social @mskcancercenter.bsky.social #NIH #NCI www.nature.com/articles/s41...

27.08.2025 17:18 β€” πŸ‘ 68    πŸ” 24    πŸ’¬ 6    πŸ“Œ 1
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Finding moments of peace πŸ’•πŸ’•

24.08.2025 17:42 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Flyer for the Graduate Student Mentorship Initiative webinar series on "Applying to Graduate Programs in STEM". This webinar will go over demystifying the application process on Thursday, August 28th, 2025 at 5.30pm ET. 

The two speakers pictures, titles, and affiliations are listed. There is a list of sponsors and text that says register for zoom link.

Flyer for the Graduate Student Mentorship Initiative webinar series on "Applying to Graduate Programs in STEM". This webinar will go over demystifying the application process on Thursday, August 28th, 2025 at 5.30pm ET. The two speakers pictures, titles, and affiliations are listed. There is a list of sponsors and text that says register for zoom link.

πŸŽ“ Planning to apply to STEM graduate programs?

Join us for our webinar: β€œApplying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET.

Gain key insights on:
βœ… Grad school application timeline
βœ… How to choose the right program

πŸ”— Register: eventbrite.com/e/gsmi-2025-...

17.08.2025 21:43 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

I cannot even imagine having a new lab rn.... sending you good vibes!

Delaying until 2026 market to hopefully let this shake out a bit more. But def applying outside the US too. 🫠

30.07.2025 13:12 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

oh I will resubmit! (tho the NCI is just going to be more competitive now...) but the hope of finding a faculty position is at an all time low

30.07.2025 13:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

To resubmit my K or to not resubmit πŸ˜…πŸ˜…πŸ₯²πŸ₯²

30.07.2025 12:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

few outcomes, except for 99% of FDA-approved drugs, 174 recipients of 104 Nobel Prizes, training ~30K MDs and ~10K PhDs per year to enter the workforce, and a 34% reduction in age-adjusted cancer deaths since 1990 -- the largest decrease in history

29.07.2025 03:26 β€” πŸ‘ 807    πŸ” 343    πŸ’¬ 14    πŸ“Œ 9
Transforming the Approach to Cancer Epigenomic Studies – Pediatrics Nationwide

Very proud of our partner papers in @cp-cellreports.bsky.social and @cp-cellrepmethods.bsky.social from collaborative work in my lab and Benjamin Stanton's lab focused on fusion-positive #rhabdomyosarcoma. #TeamFishAndChIPs

25.07.2025 17:30 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
tol2kit for kwan lab

🚨🚨🚨 Tol2kit announcement! We have rebuilt the wiki that was corrupted a few months ago! We’re in the process of also linking it to the original address. Please visit us here:
tol2kitkwan.genetics.utah.edu
Thank you for your patience!!
#zebrafish #transgenesis #plasmids #sharing

07.07.2025 18:01 β€” πŸ‘ 43    πŸ” 19    πŸ’¬ 1    πŸ“Œ 0

10th percentile for ESI πŸ˜…

24.07.2025 13:47 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Now this was just rude @nytimes.com

14.07.2025 12:50 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I feel like he’s done an okay job so far in his career πŸ˜πŸ˜‚

11.07.2025 14:01 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Camp Zon 2025 has officially kicked off! Bittersweet to be my final year directing this amazing program β€” cannot wait for the next two weeks! #Zebrafish #Outreach 🐠

11.07.2025 13:57 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Defund the police: something that never really happened, but everybody talked about.

Defund the scientists: something that's actually happening, but almost nobody's talking about in those terms.

08.07.2025 23:55 β€” πŸ‘ 1736    πŸ” 521    πŸ’¬ 23    πŸ“Œ 10

the year 4 "can't wait to be a PI" to the year 5 "hopefully I can at least keep my current job for another year or two" senior postdoctoral fellow in 2025 pipeline

28.06.2025 15:40 β€” πŸ‘ 84    πŸ” 12    πŸ’¬ 2    πŸ“Œ 0

WHAT. Below the minimum? When the minimum is not even acceptable?!

25.06.2025 21:54 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype AbstractImmune checkpoint blockade (ICB) has revolutionized cancer treatment. Unfortunately, the inability of lymphocytes to infiltrate the tumor nest, a phenomenon known as immune exclusion, drastica...

πŸ†• Our back-to-back papers reveal a surprising villain in ICB resistance: NK cells.

🧬 Targeting regulatory NK cells may boost T cell–driven immunotherapy.

#Immunotherapy #CancerResearch #ICB #NKcells #Melanoma #CD8Tcells

18.06.2025 13:36 β€” πŸ‘ 11    πŸ” 2    πŸ’¬ 3    πŸ“Œ 0

Your silence most offends me

13.06.2025 18:07 β€” πŸ‘ 456    πŸ” 84    πŸ’¬ 7    πŸ“Œ 7
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Taking back mojo dojo casa house. #NoKings

14.06.2025 00:21 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
DaniocellDesktop logo, depicting a fish on a laptop screen.

DaniocellDesktop logo, depicting a fish on a laptop screen.

If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)

13.06.2025 14:30 β€” πŸ‘ 80    πŸ” 41    πŸ’¬ 4    πŸ“Œ 5

This happens tomorrow, still time to register, free webinar, cutting edge zebrafish cancer model stories! Come join us!

27.05.2025 14:02 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

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