BatResearch - A.Prof. Aaron Irving

Most entertaining talk so far at #IBRC2025 by Fauzan.

After 11 years, Aaron and I tag teamed a joint seminar on Genotype to Phenotype: Bat immunity at #IBRC2025

@batresearch.bsky.social
@ibrc2025.bsky.social

Day 4 #IBRC2025

If you don't catch me at #SMBE2025 in Beijing on Tuesday maybe you'll catch me at #UQ or #IBRC2025 in Cairns, Australia the week after! IBRC made pretty promo pictures for each talk.

Nipah virus infects another in India's hot spot The man's illness was found during monitoring contacts of his father who recently died from a Nipah infection.

Nipah virus infects another in India's hot spot www.cidrap.umn.edu/nipah/nipah-...

While I've been at talks all morning, #ASV2025 just officially started, with an inspiring virologist: Charlie Rice. #Virology

#SMBE2025 Symposium 20: Thematic symposium: evolution of immunity

🔗 smbe2025.scimeeting.cn/en/web/program/25070

CDC vaccine advisory committee to review long-approved immunizations A leader of the CDC's reconstituted vaccine advisory committee said the panel would start a review of long-approved shots.

Yesterday #CDC posted an extraordinary (also thorough & very useful) pre-buttal of claims about thimerosal in flu vaccines that will be made tomorrow at #ACIP. #HHS made CDC take it down.
Never a dull moment these days.
www.statnews.com/2025/06/25/c...

#postdoc #virology #immunology #pandemicpreparedness #comparativeimmunology

Paul and Doug worked on this for a long time. Good to see it out!

Interferon-epsilon, an estrogen-induced type I interferon, is uniquely exploited by Neisseria gonorrhoeae via effects on sialic acid metabolism Kurt-Jones et al. examined IFN-ε, a hormone-responsive type I IFN expressed by genital epithelial cells, during Neisseria gonorrhoeae (Ng) infection. They demonstrated that mice lacking IFN-ε exhibit ...

Interferon-epsilon, an estrogen-induced type I interferon, is uniquely exploited by Neisseria gonorrhoeae via effects on sialic acid metabolism
@cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...

Breakthrough in search for HIV cure leaves researchers ‘overwhelmed’ Exclusive: Melbourne team demonstrates way to make the virus visible within white blood cells, paving the way to fully clear it from the body

www.theguardian.com/global-devel...

A crazy week. One MSc student successfully defended. A PhD TAC agrees the student can submit. AI (student)-assignmemts marked and the Center for Infection, Immunity & Cancer symposia successfully concluded..

⚠️ Discovery of a new mode of viral transmission:

Deltaviruses spread through a viral Trojan Horse !

These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!

www.biorxiv.org/content/10.1...

A thread 1/14

#CSHA #Suzhou #CellDeathandInnateImmunity

A positive-sense single-stranded RNA virus acquired a negative-sense open reading frame through recombination Author summary The discovery of brine shrimp virga-like virus 1 (BSVV1) challenges the conventional view that positive- and negative-sense RNA viruses are evolutionarily independent. Through genomic a...

Recombination between positive-sense and negative-sense RNA viruses: journals.plos.org/plospathogen...

We look forward seeing you tomorrow for Prof. Sampson's webinar on "Developing Research Capacity inAfrica: Focus on Pathogen Bioinformatics and Vaccine Development". Register: www.zoomgov.com/webinar/regi.... @sbvirologia.bsky.social @amersocvirology.bsky.social @mauriciolnogueira.bsky.social

CONFERENCE announcement: Two upcoming bat meetings. Come join us to learn all things about bats in Chicago and Cairns.

Measles cases top 350 in Texas-New Mexico measles outbreak

Measles cases top 350 in Texas-New Mexico measles outbreak www.cidrap.umn.edu/measles/meas...

Postdocs are not enrolled in a degree, they earn a salary. They are 'staff' too. The postdoc layoffs were not mentioned in this article.

| Microbe TV Donate to MicrobeTV Featured Video TWiV reviews freezes and unfreezes of US government grants, how prior COVID-19 vaccination prevents over-reaction of the innate immune response during infections, an...

If you want an unbiased tear-apart of our latest nature paper - check out @microbetv.bsky.social
's views on TWIV. TWiV 1191: The pandemic duo microbe.tv/twiv/twiv-11... (starting at 49:53)

Aus and China also run on fixed rates for indirect costs. I feel the US will need some sort of city-loading but a balanced fixed rate would suffice.

retrospectively without any leadin. People will lose jobs over this. Struggling departments will shut. A long term plan to reduce the indirect costs to a national, acceptable, standard would work. Being gungho will destroy academia in the US.

Never having worked in the US, I never realized that indirect costs could escalate to 70% of direct costs. Personally I think this is insane and a gross miss-appropriation of funding by administration. That being said, 15% is not enough by any means. It certainly cannot be implemented

Bat genomes illuminate adaptations to viral tolerance and disease resistance Nature - A systematic analysis of 115 mammalian genomes, including 10 new bat genomes, reveals prevalent positive selection in immune genes in bats and shows key adaptations in the antiviral gene...

The main article itself is openaccess rdcu.be/d7W2Y

Viral tolerance enabled by a bat-specific genomic tweak Comparative genomics reveals how virus-carrying bats resist disease.

Despite carrying lethal pathogens, bats rarely develop disease — a phenomenon that has intrigued scientists for decades

https://go.nature.com/4hBWzL0

How flight helped bats become invincible to viruses The mammals carry immune adaptations that emerged when their ancestors took to the skies.

A news article for a lay summary also: www.nature.com/articles/d41...

We're new here—help us spread the word! 🦇 🚀 Please like, follow, and share as we build our presence. We don’t have all the handles yet, so it is difficult tag everyone just yet!! If you are here - let us know 🙌💙

Viral tolerance enabled by a bat-specific genomic tweak Comparative genomics reveals how virus-carrying bats resist disease.

And a good quick News & Views summary on our latest work : www.nature.com/articles/d41...

Bat genomes illuminate adaptations to viral tolerance and disease resistance - Nature A systematic analysis of 115 mammalian genomes, including 10 new bat genomes, reveals prevalent positive selection in immune genes in bats and shows key adaptations in the antiviral gene ISG15 that ai...

Happy to report that our work on immune system adaptations in bats is now out in @nature.com 🦇🧬 www.nature.com/articles/s41... @ariadnamorales.bsky.social @batresearch.bsky.social @virology.bsky.social @DGKontopoulos.ecoevo.social.ap.brid.gy @sgn.one @bat1kgenomes.bsky.social Read more ...