Laura Mydlarz's Avatar

Laura Mydlarz

@lauradmydlarz.bsky.social

Professor, Associate Dean, Coral disease and immunology, teacher, mentor, sponsor Insta @themydlarzlab

1,287 Followers  |  81 Following  |  14 Posts  |  Joined: 19.09.2023  |  1.8532

Latest posts by lauradmydlarz.bsky.social on Bluesky

The model was tested with field samples and validated, and had a classification rate of 98.95% (AUC) and an overall error rate of 0.0754! We hope this work proves to be a valuable tool for the coral research community and a model for others to apply machine learning to coral disease research.

01.09.2025 21:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

What we did:
Using coral gene expression data, we identified gene biomarkers through logistic regression and differential expression statistics. The biomarkers were used to build a Partial Least Squares Discriminant Analysis (PLS-DA) predictive model that distinguished between the two diseases.

01.09.2025 21:49 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Leveraging machine learning to classify and characterize gene expression patterns in two coral diseases

The Mydlarz Lab has a second coral machine learning paper out this month! @emily-vanburen.bsky.social developed a diagnostic tool that classifies two coral diseases: white plague and #SCTLD. 463 genes, some involved in inflammation and protein trafficking, characterized the diseases.
rdcu.be/eCNic

01.09.2025 21:43 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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@kelseybeavers.bsky.social found evidence of dysbiosis between the coral host and Symbiodiniaceae and describes the metabolic and immune shifts that occur as the holobiont transitions from healthy to disease. See her beautiful models in the paper!

31.07.2025 18:56 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Machine learning reveals distinct gene expression signatures across tissue states in stony coral tissue loss disease | Royal Society Open Science Stony coral tissue loss disease (SCTLD) has rapidly degraded Caribbean reefs, compounding climate-related stressors and threatening ecosystem stability. Effective intervention requires understanding t...

Excited for a new Mydlarz Lab paper using Machine Learning to analyze coral transcriptomic data! @kelseybeavers.bsky.social used support vector machine recursive feature elimination combined with DEG analysis to describe SCTLD in coral. royalsocietypublishing.org/doi/10.1098/...

31.07.2025 18:56 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Post-doc position!

07.04.2025 11:53 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

About 3 years ago i agreed to update the Encyclopedia of Immunobiology chapter on Cnidarian Immunity. It turned into a labor of love because so many new discoveries had been made since it was written in 2016!
We hope this is a valuable resource for everyone!
www.themydlarzlab.com/uploads/5/2/...

22.01.2025 15:47 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Excited that Kelsey Beavers will defend her PhD Monday 2pm central. DM me for Teams link if you want to hear about her amazing work on Stony coral tissue loss disease!

28.03.2024 00:40 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Come join our amazing team and join a multidisciplinary dynamic lab with a great PI!

30.11.2023 17:27 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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A bold plan to 3D print artificial coral reef UTA team is 3D printing material that mimics ancient Roman concrete to restore coral reefs

A new venture for me! Collaboration with colleagues in engineering to test concrete formulations as potential artificial reefs.

www.uta.edu/news/news-re...

24.10.2023 21:09 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Fun at UTArlington planetarium watching the eclipse with the community! We got 80% coverage here in DFW. Love that my teen daughter and her friends thought it was so cool!

14.10.2023 21:34 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Science | AAAS

Happy to see this paper scim.ag/4jh from Steve Vollmer's lab with exciting data showing coral disease resistance can be linked to SNPs in 4 immune genes. See mine and Erinn Muller's Perspective in Science Magazine scim.ag/4ji
for the big picture of what this means for restoration efforts.

02.10.2023 17:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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@kelseybeavers.bsky.social giving an amazing talk at the Texas Advanced Computing Center symposium for Texas researchers! We had a great time visiting with everyone and seeing our server, Frontera ! @emily-vanburen.bsky.social

28.09.2023 23:50 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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The Mydlarz lab took photos for @keishabahr.bsky.social lab colorimetry project this summer and had a lot of fun doing it! They need more photos especially during this bleaching event. See info below.

21.09.2023 16:35 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1

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