David Katz

Really looking forward to visiting Rutgers and @barrlab.bsky.social tomorrow!

a colorful background with the words stay tuned written on it ALT: a colorful background with the words stay tuned written on it

If the same thing is true in the corresponding human patients, might it be possible to revert cognitive/behavior deficits in the human patients also?

the man is wearing a suit and tie and clapping his hands . ALT: the man is wearing a suit and tie and clapping his hands .

So, expressing germline genes in neurons can block their function in a way that is reversible if you shut off the inappropriate transcription

a man in a tuxedo and top hat is pointing a gun with the hashtag trendizisst below him ALT: a man in a tuxedo and top hat is pointing a gun with the hashtag trendizisst below him

Turning off the ectopic germline gene expression in the neurons of worms that already have a chemotaxis behavior defect, reverses the behavior back to normal

So, could the chemotaxis behavior defect be due to an ongoing defect in an intact nervous system? If so, might it be possible to reverse the chemotaxis behavior defect even after the nervous system has fully formed?

And an intact nervous system

No changes in the embryonic lineage

a picture of a minion with the words whaaat written on it ALT: a picture of a minion with the words whaaat written on it

Progeny of spr-5 (lsd1) and met-2 (setdb1) double mutants have germline genes expressed in somatic cells, which causes a severe chemotaxis behavior defect, but surprise...

The invariant C. elegans lineage and adult nervous system provide the perfect opportunity to find out how every cell responds to inappropriately inherited chromatin and altered transcription

a black and white photo of the milky way galaxy with the words `` you are here '' written on it . ALT: a black and white photo of the milky way galaxy with the words `` you are here '' written on it .

Ever wonder how something as broad as a chromatin mutant causes cell specific phenotypes?

Very excited to share our very exciting story on how misinherited chromatin affects individual cells to cause a behavior defect in C. elegans (a thread👇) www.pnas.org/doi/10.1073/...

So proud of my graduate student Monica Reeves for winning program student of the year in the Genetics and Molecular Biology program at Emory University @emory-gmb.bsky.social

Really cool. Looking forward to reading it. The Peters’ lab publishes amazing science.

A lot of important views expressed here. I am just curious how the potential to flood the zone with fake papers feeds into all of this?

C. elegans initiating a small RNA response

Very excited to be back at the Epigenetics GRC, this time in Barcelona! #epigeneticsgrc2025

Stand up for science. Stand up as if our lives and our economy depend on it. Because, actually, they do. #standupforscience

Quiet. Don’t tell anyone.

Thank you. I will put my head down and continue to do the best science that I can.

Harmit please tell us that it is all going to be alright.

Something seems to be wrong with the action network link, but the YouTube link for the lecture seems to be fine

Excited to be sharing the science from my lab on epigenetic inheritance and Alzheimer’s disease with the community. If you want to watch, here is the link www.youtube.com/live/O4AsL8m...
@standupforscience.bsky.social @sci4ga.bsky.social #StandUpForScience actionnetwork.org/events/teach...

Looking forward to engaging with the community and telling people about our science.

Great idea.

Excited to be talking to the community about our work and about why funding science is so important. Come join us! @standupforscience.bsky.social @sci4ga.bsky.social

Perhaps future IWMs could end in the evening so more of a full audience could get to enjoy amazing talks like this one?

Absolutely amazing talk from Junho Lee at #worm25 on flying dauer worms!

The amazing tradition that is Worm Show!

Worm folks are the best folks!! And the proof lies in the twenty year tradition of WORM SHOW on the last night (all thanks to the heroic efforts of Morris Maduro & Curtis Loer)
🪱🪱🪱🪱🪱🪱🪱🪱

The incredible worm community! #worm25