Hugh Thomas

I’m here in sunny Amsterdam on behalf of @lancetgastrohep.bsky.social for another stacked #EASLCongress 👋

Email or DM or just say hi to chat about submissions 🙌

What a flex 😂

Waitrose recalls ZOE Daily 30+ 7 Day because of possible presence of small stones and small pieces of metal

The true benefit of ZOE Daily 30+ actually lies in the small pieces of metal and stones that some lucky customers get to consume

www.food.gov.uk/news-alerts/...

From H pylori prevalence to diet and #IBS, via #HCC screening and viral #hepatitis, this is LancetGastro2024, as visualised by @mempathie.bsky.social

Thank you authors, reviewers, advisory board members, and all at @thelancet.bsky.social involved in getting an issue published each month!

The Adam Curtis doco you really didn't know you needed

Good article in Nature on the INSPECT-SR project I had the pleasure of contributing to (preprint now at doi.org/10.1101/2024...)

Most problematic trials probably have little clinical impact on their own. But sys-revs that inadvertently include them risk 'laundering' their findings to wide audience!

What an entrance!

Ouch. Only 16 MDPI and 22 Frontiers journals to remain at level 1 (includes Frontiers in Gastro)

🙏 Thanks @themoorelab.bsky.social!

A well balanced editorial from the team at the Lancet Gastroenterology & Hepatology this month on the contentious topic of UPFs.

💯 in agreement:

"Pleas to overhaul the food system to mitigate the specific harms of UPFs are well meaning but overly reliant on limited data...

Amazing to watch commentators and outlets attribute these findings to UPFs and seed oils when the study doesn't even look at this. The assumption that eating more linoleic acid -> higher tissue arachidonic acid enrichment has fueled so many handwavey hypotheses despite metabolic regulation

Think this article yields too many qs about underlying observational work to be v useful

Eg, is this an attempt to isolate specific UPF effects (if so, do they relate to all UPF products)? Or do effects reflect overall nutritional content of diets (if so, invocation of UPF nomenclature misleading)?

As if it needed illustrating that Bluesky is the new domain for sharing and discussing scientific content ⬇

The original article will live long in the memory, featuring earnest claims of brain-resident chloroplasts

Now on Bluesky 👇

For those of you who keep asking;

No we don't capture attention from clinical guidelines by "walking around hospitals listening for DOIs and writing them all down."

NB: palatability defined by sugar/fat content, not subjective rating - all diets were perceived to be similarly pleasant/filling

Interim data (n=18/36) from new @kevinh-phd.bsky.social crossover trial

clinicaltrials.gov/study/NCT052...

⬆ 1-week energy consumption w/ #UPF diets high in energy density/palatability (UPF hh) & high energy dense/low palatability (UPF hl) vs MPF & UPF diet low in energy density/palatability

Tuning into #IBResearch #UltraProcessedFood conference today. The day kicks off with the same tired COI attacks. Deeply dispiriting.

Anyone who has followed this story won't be surprised to hear that simufilam missed both phase 3 co-primary endpoints. A bleak tale of fraud and threats finally brought to a close, years too late. www.cassavasciences.com/news-release...
www.science.org/content/arti...

No permissions for external viewers

Paediatric acute liver failure: a multidisciplinary perspective on when a critically ill child is unsuitable for liver transplantation Paediatric acute liver failure is a devastating condition with high morbidity and mortality, which is challenging to manage for the hepatologist, intensivist, and associated specialists. Emergency liv...

New at The Lancet Child & Adolescent Health — Paediatric acute liver failure: a multidisciplinary perspective on when a critically ill child is unsuitable for liver transplantation

www.thelancet.com/journals/lan...

#LiverSky

There's an awful lot more data to explore, of course.

Research impact assessment by citations alone is far too narrow, and biases 'impact' towards certain hot topics - here's hoping that being able to assess policy and now clinical guideline citations will even out the playing field!

I'm a big fan of the new longitudinal citation visualisation for all altmetric items - this has been around for a few months now, and it enables a much better snapshot of impact

Which papers were cited quickest?

Unsurprisingly, this outcome is dominated by COVID papers.

This letter on preventing COVID-19 in decomp cirrhosis (doi.org/10.1016/S246... was cited 36 days publication by AFEF guidance on care of patients with liver disease dx.doi.org/10.1016/j.cl...

Which papers are cited most?

3 papers appear in 7 guidelines:
📃A pair of 2016 RCTs on TAF vs TDF in HBeAg +ve and -ve patients linkinghub.elsevier.com/retrieve/pii...
linkinghub.elsevier.com/retrieve/pii...
📃A comment on Liver injury in COVID-19 www.thelancet.com/journals/lan...

Which guidelines cite the most #LancetGastroHep papers?

It's a two-way tie between two hepatitis B guidelines: the 2022 KASL CPGs for chronic hepatitis B (dx.doi.org/10.3350/cmh....) and the 2024 @who-global.bsky.social hepatitis B guidelines (iris.who.int/bitstream/10...), each citing 10 papers

Since #LancetGastroHep launched in mid 2016, altmetric counts 303 clinical guideline 'mentions' of our content. The first, in 2018, was a SRMA on the burden of pancreatic disease, which appeared in an #AGA technical review on initial mgmt of acute pancreatitis www.thelancet.com/journals/lan...

Guideline mentions are counted for each paper cited, and for each guideline doing the citing: 174 different #LancetGastroHep papers are cited by 170 discrete guidelines

@altmetric.com have rolled out data for article citations in clinical guidelines, giving new insight into clinical impact for publications, and I couldn't resist having a dig into it for #LancetGastroHep