rocky

AlphaFold developer Google DeepMind to fund CASP as NIH funding falls short Protein structure prediction contest CASP gets temporary funding from Google DeepMind as NIH grant runs out.

NEW from me at STAT:

We've learned that DeepMind is going to fund CASP, the protein structure competition that brought Google DeepMind's #AlphaFold to prominence (and a Nobel Prize), as its NIH funding runs out.

More @statnews.com:
www.statnews.com/2025/07/21/c...

🖥️🩺🧪🧬 #bioML

Interviews with Authors - YouTube

Just realised that we've been doing Interviews With Authors on YouTube for a whole year!

I'd really appreciate receiving comments about these, e.g. suggest a structural biologist you would like us to interview

Here's a playlist with all the videos we've done so far: www.youtube.com/playlist?lis...

a yellow sign that says we 're hiring ALT: a yellow sign that says we 're hiring

Nature Methods is hiring!
We are seeking a new editor with expertise in microscopy, imaging technology, and/or cell biology. The position is available in NYC/Jersey City or Shanghai/Beijing on a hybrid working model.
Apply by August 3!

springernature.wd3.myworkdayjobs.com/SpringerNatu...

When I arrived to NYC as a postdoc, NYSBDG was my first local meeting, and I was blown way by the world-class quality of the science.

It's a great opportunity to meet the local #structbio & #cryoem community, and it's coming up in two weeks, so register now at the eventbrite link below!

Picture of an abandoned ice cream cart, with words “We are not free until everyone is free” at the top of the image

We are not free until everyone is free.

From @votolatino.bsky.social

The Klem Lab at LSU is hiring a postdoctoral researcher in computational biochemistry!
Application info: klem-research-group.github.io/join/
♻️ Please share with anyone who might be interested! #chemjobs #postdoc #compchem #biochemistry #enzymes

Meet the speakers of our anniversary symposium "Advances in Structural Analysis of Biomolecules: From Subcellular Imaging to Drug Design"

cbc-cpc2025.org

October 23-24, 2025, Berlin

Please like and share! #ChemBioPhys2025

Mechanisms of Ion Permeation in the AMPA Receptor Ion Channel Excitatory synaptic transmission in the human nervous system is mediated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs), tetrameric ligand-gated ion channels localized in t...

Here is our foray into the biophysics of cation permeation in AMPA receptors, now available as a preprint on @biorxivpreprint.bsky.social:

www.biorxiv.org/content/10.1...

Led by former student Dr. Alejandra Montaño Romero, in collaboration with Albert Lau!

I am really happy to share with you our latest publication on turning the inhibiting nucleation effect of silica gel on protein crystallization by increasing the hydrophobicity through controlled functional modification. #chembio, #ge3c-rseqf

pubs.acs.org/doi/full/10....

UCSF ChimeraX version 1.10 has been released!

www.rbvi.ucsf.edu/chimerax/dow...

Calling all structural biologists in the NYC metro area! The nysbdg.bsky.social is back for in-person events!

Register here 👉🏼 buff.ly/dGmJeau

I look forward to seeing you there! 😎

#structuralbiology #cyrstallography #cryoEM #NMR
#chromatography #proteinpurification #AKTAsystems

I had a great day at my first New York Cryo-EM Meeting. Thanks to @fravallese.bsky.social and Bill Rice for hosting as well as a fabulous keynote talk by @cryoet.bsky.social. Looking forward to chatting with more structural biology community members at NYSBDG and NYCISB25! #cryoEM #cryoET

U.S. strikes Iran's nuclear facilities Trump's direct intervention marks a historic escalation in the Middle East.

BREAKING: U.S. strikes Iran's nuclear facilities

The U.S. Senate is currently considering a budget reconciliation bill that quietly includes language that could devastate our public lands. It would:
- Make over 250 million acres of public land eligible for sale
- Mandate the sale of at least 2 million acres of Forest Service and BLM land

New paper out from the Mittag lab: www.biorxiv.org/content/10.1...
New adventures in understanding structure and function of SPOP, which involve donuts! 🍩

Congratulations to first authors Matt Cuneo, Ömer Güllülü and Mohamed-Raafet Ammar, and all other authors!

Jay, please stop gaslighting early career researchers.

Calling all structural biologists in the NYC metro area! The @NYSBDGrp is back for in-person events!

Register here 👉🏼 buff.ly/dGmJeau

I look forward to seeing you there! 😎

#structuralbiology #cyrstallography #cryoEM #NMR
#chromatography #proteinpurification #AKTAsystems

Temporal gating of nuclear import: How Merkel cell polyomavirus exploits the cell cycle for nuclear entry Author summary Merkel cell polyomavirus (MCPyV) causes a rare but deadly form of skin cancer called Merkel cell carcinoma. However, many aspects of its infectious life cycle are unclear, including how...

I’m excited to share the first publication from my lab on the unexpected strategy that MCPyV, a cancer-causing virus, uses to enter cells. This was truly a team effort and I am so grateful for each of the brilliant women who contributed to this research project. journals.plos.org/plospathogen...

Postdoc positions open in my lab (Francis Crick Institute) to study

1. initiation of DNA replication.

2. chromatin replication/epigenetic inheritance.

Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.

Deadline 3 August 2025.

crick.wd3.myworkdayjobs.com/External/job...

Small angel X-ray scattering

Demis Hassabis this April: AlphaFold is helping to bring the end of *all* disease "within reach, maybe within a decade or so." I doubt there is a single drug developer who thinks this. Seems a bit irresponsible to me.

So grateful to #NASA to end the week with the arrival of the award documents for our new #Exobiology grant. So excited to work together with @liamlongo.bsky.social & @marieskepo.bsky.social on the emergence and evolution of phosphate binding at the origin of life. Thank you for supporting our work!

What? Some good news on a Friday?

Parent Fellowship Notices of Funding Opportunities are up!

F30, F31, F32, F33

grants.nih.gov/grants/guide...

Graduate Field Coordinator-Department of Chemistry and Chemical Biology Graduate Field Coordinator-Department of Chemistry and Chemical Biology The Opportunity The Department of Chemistry and Chemical Biology is seeking a dedicated and detail-oriented Graduate Field Coord...

Hello BlueSky 🦋 I'm the Director of Graduate Studies in Cornell Chemistry. We're hiring a new Graduate Field Coordinator to help support our graduate program. Please apply or repost if you know someone great! tinyurl.com/3znxx4bh

Day 2 of the Summer School is about molecular recognition and docking 🤝

@amjjbonvin.bsky.social introduces #HADDOCK to predict interactions between: proteins, nucleic acids, glycans and small molecules

For further flexibility and customisation check out HADDOCK3 ➡️bit.ly/4mQLZn7

Imaging of specialized plant cell walls by improved cryo-CLEM and cryo-electron tomography Cryo-focused ion beam scanning electron microscopy (cryo-FIBSEM) has become essential for preparing electron-transparent lamellae from cryo-plunged and high-pressure frozen specimens. However, targeti...

Check out our latest work, featuring beautiful, first-of-their-kind cryo-tomograms of crucial plant cell wall modifications, Casparian strips, suberin lamellae, lignified xylem walls and more! From our Electron Microscopy Facility led by @chgenoud.bsky.social

www.biorxiv.org/content/10.1...

Simons Graduate Fellowships in Ecology and Evolution The purpose of these awards is to provide support for students entering U.S.-based Ph.D. programs with a plan to perform research in ecology and evolution. While we will consider all projects in ecolo...

Simons Graduate Fellowships in Ecology and Evolution www.simonsfoundation.org/grant/simons...
Application Deadline July 31, 2025

All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!

Shit.

Mark your calendar and spread the word ...
@vubasicsciences.bsky.social @vanderbiltvicb.bsky.social @vucellimaging.bsky.social @vandybiomed.bsky.social

#structuralbiology #AI #research #cryoem #cryoet #protein