Walzer Lab

Cryptosporidium oocyst wall proteins are true components of the oocyst wall and COWP8 is not required for parasite transmission Author summary Infection with Cryptosporidium causes diarrhoea, which can be fatal for malnourished children or people who are immunocompromised. There is no vaccine or effective medicines available t...

Incredibly proud to share that our work on Cryptosporidium Oocyst Wall Proteins is published in
@PLOSPathogens
journals.plos.org/plospathogen...

Led by previous PhD student
@BacchettiRoss
and carried on by current PhD student, Sarah Stevens.

Can’t wait for all things Cryptosporidium!

The @veupathdb.org user comments campaign at #MPM2025 yielded 200 user comments from 66 attendees! Thanks, contributors 💐

For example: a comment on gene cgd5_3570 on CryptoDB pointed out that GGC proteins exhibit male-specific expression according to single-cell RNA seq. Good to know!

Super user friendly, and easy to visualize the highest expressing cells!

The Walzer Lab is #hiring! We are recruiting a lab technician and graduate students to work on Cryptosporidium development at Clemson University! Join our lab with an EPIC group of colleagues! #parasitesrule

Targeted CRISPR screens reveal genes essential for Cryptosporidium survival in the host intestine - Nature Communications Cryptosporidium is an important threat to public health, yet it lacks a robust genetic toolkit. Here, Watson et al. introduce a targeted CRISPR-based screening method to identify parasite genes that a...

Now available in a polished format! An important step toward accelerated functional genomics for the Cryptosporidium parasite. Brought to you by the incomparable @lucy-watson.bsky.social
www.nature.com/articles/s41...

Come work with Fungal Group at UGA!

Congratulations on this amazing work!

Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis Influenza viruses replicate and transcribe their genome in the context of a conserved ribonucleoprotein (RNP) complex. By integrating cryo–electron microscopy single-particle analysis and cryo–electro...

Excited to share our new @science.org paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals.
www.science.org/doi/10.1126/...

Recently, we found out that our R01 funded through PAR-22-241 was withdrawn by NIAID as the NIH no longer prioritizes research programs related to DEI. This has been devastating news for our young research group, and we are now trying to scram together for a path forward 🧵1/12