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@sangishyam.bsky.social

8 Followers  |  71 Following  |  1 Posts  |  Joined: 21.10.2024  |  1.3538

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That is interesting!

04.02.2025 19:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Guidance for protocol content and reporting of factorial randomised trials: explanation and elaboration of the CONSORT 2010 and SPIRIT 2013 extensions This report presents the explanation and elaboration paper for the CONSORT (Consolidated Standards of Reporting Trials) 2010 and SPIRIT (Standard Protocol Items: Recommendations for Interventional Tri...

Working on a factorial trial? The Explanation and Elaboration paper for the CONSORT and SPIRIT factorial extensions is now out in @bmj.com

It includes:
-examples of how to report factorial trials
-a methodology summary around the design/conduct/analysis of these trials

www.bmj.com/content/388/...

04.02.2025 11:03 β€” πŸ‘ 17    πŸ” 11    πŸ’¬ 0    πŸ“Œ 0
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If you were taught to test for proportional hazards, talk to your teacher.

The proportional hazards assumption is implausible in most #randomized and #observational studies because the hazard ratios aren't expected to be constant during the follow-up. So "testing" is futile.

But there is more πŸ‘‡

03.02.2025 14:51 β€” πŸ‘ 79    πŸ” 19    πŸ’¬ 4    πŸ“Œ 1

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