Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de

Beautiful limbs! HCR?

To the receiver, it came across like you were super charged and full of self-motivation. Keep looking gorgeous 😂

Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1936

How dit life originate in our planet? How can we create it in the lab?Our @royalsocietypublishing.org Theme Issue "Origins of Life: the possible and the actual", coedited with @sfiscience.bsky.social C Kempes and Susan Stepney is out! royalsocietypublishing.org/toc/rstb/202... @manlius.bsky.social

looking forward to catch up with you and @philipcball.bsky.social there 🤓.

Fully-funded 4-year PhD Opportunities available at the @crick.ac.uk , including a project in our lab on human #embryomodels Feel free to share with anyone interested, and apply through the online portal before 5th November! 👏

www.crick.ac.uk/careers-stud...

Hi bsky!

Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity!

w/ A. Delahaye & ‪@bensteventon.bsky.social‬

shorturl.at/v01DO

Shiny happy people ✨ Wish I could have been there too, looks like a great meeting!

Congratulations! It was much needed. Beatiful perspective.
@pauformosa.bsky.social @perez-carrasco.bsky.social

Gastruloids employ an alternative morphogenetic route to generate a posterior body axis on adherent substrates Morphogenesis emerges from the integration of genetic programs with environmental signals, yet studying this interplay in embryos remains challenging due to the inherent complexity of embryonic system...

shorturl.at/v01DO

Good PhD and Postdoc opportunity in a vibrant multidisciplinary lab. Check it out if you are looking for your next move!

Now, this is a very good perspective on dynamical Systems for cell fate decision. Congratulations to the authors!

Israel committing genocide in Gaza, say Israel-based human rights groups Reports detailing intentional targeting of Palestinians as a group, and systemic destruction of Palestinian society, add to pressure for action

“I think every human being has to ask himself: what do you do in the face of genocide?”

“It couldn’t happen without the support of the western world. Any leader that is not doing whatever they can to stop it is part of this horror.”

www.theguardian.com/world/2025/j...

Can robots in a swarm act like the cells of an organism? Thanks to Sedeer El-Showk for the new article in @nature.com, which highlights the work of a number of research groups, including our own, on how “Robots demonstrate principles of collective intelligence”. www.nature.com/articles/d41...

Development is in good shape and in good hands! Congratulations for your work.

Nice! In-toto 3D imaging is definetely the way to go.

Man! your frying pan is "gastrulating" like a chick embryo www.sciencedirect.com/science/arti... . Did you cook chicken dumplings? 🤣

Can using synthetic approaches to build biology help teach us the design principles of how embryos build themselves? 👷‍♀️🔧

If this is a question that interests you, come and share your thoughts at this Royal Society Workshop on Generative Biology

royalsociety.org/science-even...

Organizers and self-organization in developmental biology This collection highlights papers studying self-organization, symmetry breaking, and developmental organizers.

Attention #devbio and #stemcell crew! @natcomms.nature.com is looking for submissions related to developmental organizers, self organization, and symmetry breaking. More details on the collection page. www.nature.com/collections/...

Congrats James, David, and the whole team! Great to see scRNA-seq getting closer to dynamical systems theory. Looking forward to diving into it this weekend, perfect distraction from the heat of Seville. 🔥

Looks great! Congratulazioni. 👏

📣 Preprint alert! We developed a framework to uncover Coherent Structures in flows on dynamic surfaces—revealing dynamic attractors, repellers and deformation directions in nematic vesicles, pancreatic spheroids, and beating zebrafish hearts. @sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...

Yes you are right! but maybe "meaning" for a dynamical system comes only in a context, which is just other dynamical systems. Perhaps we lack words to refer to dynamical systems that work all together across scales. I mean an organoid evolves towards the direction of an organ but without context...

But i the end, misusing these words, all that it does is to humble human exceptionalism, revealing shared principles across physical, chemical, biological, and human domains. And human beings need to be humbled a lot... So it is not that bad, I think.

2/2 While debates persist on whether such emergent trajectories imply agency, attributing "will" to self-organizing systems I think it is just because we lack language to describe such self-organizing behaviors.

1/2 This was already brought up by Aristotle, in his Physics (c. 350 BCE) with the teleological cause, or final cause, positing that organisms possess an entelechy: an inner drive toward their ideal form. For example, a bird strives to develop wings for flying, its entelechy guiding the process.

Become the scientist you've been dreaming. Grow with us! #JoinUs in Dresden @imprs_mpicbg @mpicbg for #fullyFunded PhD positions! applications open until Oct 30th👇 digsbb-online-application.cmcb.tu-dresden.de/ausschreibun...

I also recently moved to bsky. Nice to see you all here! 🎉

Love the work! 👏

Extended culture of 2D gastruloids to model human mesoderm development - Nature Methods This study reports an extended 2D gastruloid system for spatially modeling human mesoderm development.

Our work on mesoderm development in 2D gastruloids is now published in nature methods

www.nature.com/articles/s41...