How to keep in step when your (protein) partner speeds upβ¦
Here we investigated the adaptive remodeling of a protein-protein interaction surface essential for telomere protection.
Congrats to whole team!
www.science.org/doi/10.1126/...
@amberridgway.bsky.social
Postdoctoral researcher in Mia Levineβs Lab, University of Pennsylvania Love all things Drosophila, evolution, running and Eastenders
How to keep in step when your (protein) partner speeds upβ¦
Here we investigated the adaptive remodeling of a protein-protein interaction surface essential for telomere protection.
Congrats to whole team!
www.science.org/doi/10.1126/...
Rapid compensatory evolution within a multiprotein complex preserves telomere integrity www.science.org/doi/10.1126/... @levine-lab.bsky.social very cool work
27.11.2025 20:43 β π 27 π 14 π¬ 0 π 0An advertisement for the project Cryptc consequences of a selfish X chromosome. It shows chromosome mapping indicating many inversions, flies with eye colour phenotypes (wild-type brighter than selfish X), and sections of testes that show ordered (wild-type) or deformed structure (selfish X).
We have a funded NERC PhD studentship!
Selfish X chromosomes are these bizarre things where males carrying the selfish X suffer from imploding testes. Lots to do in this space, especially in evolutionary, stress, and infection biology.
Please share!
#PhDchat #AcademicSky @uniexecec.bsky.social
One week left to apply for this position!
11.11.2025 14:31 β π 3 π 1 π¬ 0 π 1Ichetucknee Springs State Park, a short drive from Gainesville, FL
The Hopkins Lab (hopkins-lab.com) at the University of Florida is looking to recruit a postdoc to work on the genetics of organ function and evolution across Drosophila and beyond. Please visit tinyurl.com/vcsjpmzz or email me for more info. And please RT or send to anyone who might be interested!
15.10.2025 20:42 β π 37 π 41 π¬ 3 π 2Graphical abstract: The Drosophila OSC Genome as a resource for transposon and piRNA biology. The figure illustrates the workflow and key findings. Left: De novo genome assembly using Oxford Nanopore Technologies (ONT) long reads and Hi-C data generates a phased assembly distinguishing unique (blue) and repetitive (orange) sequences. Dot plot comparison between OSC-r1.01 and dm6 reference genomes shows overall synteny with extensive structural variation. Middle: A freely accessible UCSC genome browser session displays multi-omics data tracks including gene models, transposon insertions, chromatin accessibility, transcription, small RNAs, and histone modifications. Right: New insights into flamenco piRNA cluster biology reveal >730 kb transcribed from a single promoter without major splicing. Tethering assays demonstrate long-range silencing effects across the locus, and genome browser tracks show coordinated regulation of piRNA production, transcription, and chromatin state. This resource enables comprehensive studies of transposon regulation and piRNA pathway function in a widely-used Drosophila cell line.
When transposons jump, genomes diverge - even in cultured cells.
I am happy to share our new preprint: a chromosome-scale genome assembly for Drosophila OSC cells, one of the key model systems in the piRNA field, especially for nuclear piRNA biology. π§¬π§΅ (1/12)
Front cover of the European Butterfly Red List, showing Polyommatus humedasae. The report can be downloaded at https://www.bc-europe.eu/webpage.php?name=red-list-butterflies-2025
The new European Butterfly Red List is published today, with worrying findings. Over 1/4 (28%) of Europeβs 442 species are threatened with extinction or are close to being so. The situation is far worse for our 148 endemic species, 40% are now threatened or nearly so www.bc-europe.eu/webpage.php?...
11.10.2025 09:17 β π 163 π 107 π¬ 3 π 5Great opportunity to do a PhD with me through the ILESA PhD programme in Oxford with #Drosophila #Microscopy #Genetics. Check out what the programme is about below and DM me for more information!
www.ox.ac.uk/admissions/g...
Very proud of our paper on "scrambling-by-hopping" LADs, which was just published: www.nature.com/articles/s41.... Congrats to Lise Dauban and the rest of the team β this was a real tour-de-force!
02.09.2025 17:26 β π 58 π 24 π¬ 0 π 0attention πͺ°folks. many of you received a survey from @genetics-gsa.bsky.social about potential future sites of the US Fly meeting. We are excited for #Dros26 Chicago, but future sites are in question, for many logistical reasons. GSA is hard at work planning, but we need to hear from you. please RT!
06.08.2025 17:32 β π 11 π 14 π¬ 2 π 0Huge congrats Ben, thatβs incredible news!!
19.06.2025 00:37 β π 1 π 0 π¬ 1 π 0We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.
03.06.2025 21:17 β π 83 π 115 π¬ 0 π 12Get the word out far and wide. New opportunity from the Simons Foundation in the Eco-Evo space.
2026 Simons Graduate Fellowship in Ecology and Evolution Awards, due July 31, 2025, only for incoming PhD students who plan to start their PhDs in Fall 2026.
www.simonsfoundation.org/grant/simons...
Buzzing to see this published! Before selecting my PhD, I spent three months in the Flashman lab working on this project. Since then, this novel tool has been extensively and beautifully characterized - well done to all the authors!
09.05.2025 18:27 β π 1 π 0 π¬ 0 π 0Join our team as a postdoc and explore the exciting world of transposable elements and developmental biology with us! @imbavienna.bsky.social @vbcscitraining.bsky.social
06.04.2025 16:24 β π 38 π 41 π¬ 1 π 1Join us to investigate the evolutionary-developmental basis of genital co-evolution between sexes! Strong candidates will have an interest in #EvoDevo & #SexualSelection
and Skills in #Drosophilagenetics, Transgenesis or Bioinformatics
DM for details.
tinyurl.com/yesyjyfd
Drosophila follicle showing retrotransposons (pink & yellow) expressed in somatic cells infecting the oocyte
1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. π§¬
But did you know they can also jump π£π¦π΅πΈπ¦π¦π― cells? π€―
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread π§΅π
Happy to share our Slow cooked work together with @mcgregorlab.bsky.social, @posnienlab.bsky.social , @nuneslab.bsky.social sky.social and Saad Arif and the collaboration of @maikekittelmann.bsky.social, Fernando Casares & @laurensr.bsky.social and many other friends
rdcu.be/d8whP
A scorpion embryo to brighten your day.
Purple: Pax2A. Yellow: Pax2B. Blue: nuclei.
Postdoc @ evol-lab. A Leverhulme funded 3-year postdoc studying body shape evolution (through a sexual conflict lens) on Exeter's Penryn (UK) campus. Starts April 2025. Contact David Hosken @ U of Exeter for detail.
17.12.2024 09:40 β π 19 π 32 π¬ 0 π 0This one was always a favourite of mine during my PhD studies: www.nature.com/articles/nat...
21.01.2025 13:15 β π 1 π 0 π¬ 0 π 0PhD Opportunity: Last few days to apply to join my lab to explore the co-evolution of male and female genitalia in Drosophila. Feel free to DM me for more details! π§¬π #PhDposition #EvolutionBiology #Genetics tinyurl.com/PhD-Drosophila
15.01.2025 13:23 β π 0 π 3 π¬ 0 π 0At Stockholm University, we are now starting a 2-year Masterβs programme in Evolutionary Genomics!
Topics include population genetics, phylogenetics, molecular & genome evolution, DNA sequencing, bioinformatics, and palaeogenetics.
Please spread the word!
www.su.se/english/sear...
Fantastic work!
21.12.2024 16:55 β π 0 π 0 π¬ 0 π 0Excited to share the major work of my dissertation, out now in @currentbiology.bsky.social! We use Drosophila genetics to dissect the evolution of phage-derived toxins that were horizontally transferred to insects and now function as potent anti-parasitoid defenses (1/n): tinyurl.com/2k9ypyxr
20.12.2024 17:58 β π 145 π 64 π¬ 8 π 5Love this preprint, beautiful work
18.12.2024 22:22 β π 1 π 0 π¬ 0 π 0Join us in Cambridge! This evolutionary genomics professorship (lecturer/reader level) has an emphasis on introgression and gene flow. If you study any aspect of evolutionary genomics then please apply! www.jobs.cam.ac.uk/job/49389/
18.12.2024 16:34 β π 62 π 59 π¬ 1 π 1Do you need to curate a Transposable Elements library for a new genome 𧬠or a new species ππ¦π¦? Try MCHelper.!
Very proud of my (small) contribution here. Gracias a @simonorozcoa.bsky.social y @gonzalezlabbcn.bsky.social!
genome.cshlp.org/content/earl...