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Nicholas Lawrence

@nicholasjlawrence.bsky.social

Chemistry Professor at the Moffitt Cancer Center. Views personal.

81 Followers  |  42 Following  |  15 Posts  |  Joined: 31.01.2025  |  1.9212

Latest posts by nicholasjlawrence.bsky.social on Bluesky

Great conference upcoming at UF next year!

18.09.2025 21:10 — 👍 0    🔁 0    💬 0    📌 0

Great news!

18.09.2025 21:08 — 👍 0    🔁 0    💬 0    📌 0

Congratulations Andrew!

20.08.2025 17:53 — 👍 0    🔁 0    💬 1    📌 0

Downloaded. Thanks

10.05.2025 00:10 — 👍 0    🔁 0    💬 0    📌 0
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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity Nature - An orally bioavailable small-molecule active-site inhibitor of the phosphatases PTPN2 and PTPN1, ABBV-CLS-484, demonstrates immunotherapeutic efficacy in mouse models of cancer resistant...

More info in this super Nature paper.

rdcu.be/ejc98

24.04.2025 19:58 — 👍 0    🔁 1    💬 0    📌 0
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ABBV-CLS-484 is a first-in-class, orally bioavailable PTPN2/N1 phosphatase inhibitor, being evaluated as a potential cancer immunotherapy agent. A rare example of a bioavailable active site phosphatase inhibitor. To be added to next year's lecture notes. Hoping for positive results in the clinic!

24.04.2025 19:37 — 👍 1    🔁 0    💬 1    📌 0
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Great to hear the Medicinal Chemistry of phosphatase inhibitor ABBV-CLS-484 from Abbvie's Dr. Phil Kym (to the left of Dr. Jim Leahy) last week at USF Chemistry. #DrugDiscovery, #Chemistry

24.04.2025 19:12 — 👍 0    🔁 0    💬 1    📌 0

A great event yesterday morning. Really looking forward to moving our lab to the Innovation Center next year!

23.04.2025 13:44 — 👍 1    🔁 0    💬 0    📌 0

Great to be at the topping out ceremony for the Speros Innovation Center. Looking forward to moving the lab here next year. Congratulations to all who are making this happen.

23.04.2025 13:43 — 👍 2    🔁 0    💬 0    📌 0
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Moffitt Treats First Glioblastoma Patient in Florida Using New Technology Carthera’s Sonocloud-9 could eliminate challenges presented by the blood-brain barrier

An intriguing way to open the blood-brain barrier on-demand. This offers hope for better treatments for glioblastoma and metastases in the brain and CNS.

www.moffitt.org/endeavor/arc...

16.04.2025 15:40 — 👍 1    🔁 0    💬 0    📌 0
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Our next keynote speaker, Levi Garraway, Head of Global Product Development and Chief Medical Officer at Roche, shares his inspiring career journey from academia to the biotech industry. #MoffittBoB

11.04.2025 15:03 — 👍 1    🔁 1    💬 1    📌 0

This was really good!

12.04.2025 01:22 — 👍 1    🔁 0    💬 0    📌 0

Bittersweet. But congratulations to your students and the whole cohort. Good luck to them all.

12.04.2025 01:21 — 👍 2    🔁 0    💬 0    📌 0
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Today for the 18th annual Business of Biotech, over 700 biotech executives, entrepreneurs, venture capitalists, angel investors and researchers from across the U.S. are at Moffitt for a unique opportunity to collaborate. #MoffittBoB

11.04.2025 15:02 — 👍 1    🔁 1    💬 0    📌 0

Good luck Stuart. Let them know there's plenty of opportunities for internships in all things drug discovery!

04.03.2025 21:40 — 👍 3    🔁 0    💬 1    📌 0

Well done Julian. Congratulations! All the best for retirement.

20.02.2025 15:49 — 👍 1    🔁 0    💬 0    📌 0

This is really cool. Many years ago I was one of the 4 interviewing for Julian's job. Of course, the best candidate got the the job!

20.02.2025 15:47 — 👍 0    🔁 0    💬 0    📌 0

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