Emma Cunningham, Danny McAuley, Bernadette McGuinness, David Beverland, Henrik Zetterberg, @jmschott.bsky.social, Amanda Heslegrave, Elena Veleva, Rhiannon Laban, Aoife Sweeney
17.07.2025 12:26 β π 0 π 0 π¬ 0 π 0@emsdoesscience.bsky.social
Postdoctoral Researcher at the University of Oxford, Department of Psychiatry π§ Data science, precision psychiatry, and #biomarkers, especially in #delirium, #dementia and #psychosis. Sometimes a musician π», Belfast born and bred, Views my own!
Emma Cunningham, Danny McAuley, Bernadette McGuinness, David Beverland, Henrik Zetterberg, @jmschott.bsky.social, Amanda Heslegrave, Elena Veleva, Rhiannon Laban, Aoife Sweeney
17.07.2025 12:26 β π 0 π 0 π¬ 0 π 0Read this paper Open Access in Alzheimer's and Dementia, the Journal of @alzassociation.bsky.social
Massive thanks to my wonderful co-authors for their support on this work (and throughout my PhD!) π
π― Further research into the pathways of such subtypes could pave the way for personalised delirium care and better outcomes.
πNext on the agenda - validation and assessment of differential outcomes.
π We found:
Class 1: Older, worse baseline cognition (despite exclusion of people with existing dementia), higher depression, and more signs of brain injury/neurodegeneration (GFAP, NfL, sTREM2).
Class 2: Fewer symptoms, better baseline cognition.
π» Methods
We analysed data from the PostOperative Delirium Belfast Study (led by Dr Emma Cunningham), to investigate subtypes of patients being assessed for delirium after surgery, using Latent Class Analysis (LCA).
LCA is a person-centred, unsupervised, statistical learning approach.
π§ New Research Alert!
π° Identifying subphenotypes of patients undergoing post-operative delirium assessment
π§΅Findings in this thread
#Delirium #LatentClassAnalysis #Endotypes #Subphenotypes #Geriatrics #PrecisionPyschiatry
doi.org/10.1002%2Fal...
Join us tomorrow (April 23) at 11AM ET for a great session on #delirium phenotypes.
@emsdoesscience.bsky.social @kellytoth.bsky.social @nidus-delirium.bsky.social @johndevlinpharmd.bsky.social
In just one week Emily Bowman and Kelly Toth (Potter) will highlight their research on delirium phenotypes and propose areas for future investigation.
In just one week @emsdoesscience.bsky.social & @kellytoth.bsky.social will highlight their research on #delirium phenotypes & propose areas for future investigation.
Register today: deliriumnetwork.org/webinars/upc...
@johndevlinpharmd.bsky.social @nidus-delirium.bsky.social
In the next NIDUS mentoring session, Emily Bowman & Kelly Toth (Potter) will highlight their research on delirium phenotypes and propose areas for future investigation.
In two weeks (April 23) @emsdoesscience.bsky.social & @kellytoth.bsky.social will highlight their research on #delirium phenotypes and propose areas for future investigation.
Register today:
deliriumnetwork.org/webinars/upc...
@johndevlinpharmd.bsky.social
@nidus-delirium.bsky.social
Iβll be chatting about delirium phenotyping and the upcoming NIDUS webinar on 23rd April, alongside the brilliant @kellytoth.bsky.social! Register below and see you there βΊοΈπ§
24.03.2025 20:00 β π 2 π 1 π¬ 0 π 0I completed my PhD in #delirium #phenotyping, in Belfast, where Iβm from. Iβm passionate about the use of existing data and generation of strong new datasets to find out more about the condition.
And finally in my spare time, I play the violin in the Oxford Millennium Orchestra! π»
#Introduction post!
Iβm Emily - a postdoc at the University of Oxford, Department of Psychiatry π§
Iβm currently working in precision psychiatry and data science, focussing on #biomarkers and treatment response in #psychosis.
Also super passionate about #ageing, #dementia and #delirium research