Lucas Nivon's Avatar

Lucas Nivon

@lucasnivon.bsky.social

CEO and co-founder at Cyrus Bio. Co-founder OpenFold AI bio consortium. Computational protein/biologic discovery. Rare disease, auto-immune, anti-viral, vax. PhD Harvard Biophys, Postdoc Bakerlab at UW. #Urbanism, #bikes, #democracy, #proteinai

402 Followers  |  1,014 Following  |  162 Posts  |  Joined: 04.10.2023  |  2.5141

Latest posts by lucasnivon.bsky.social on Bluesky

This is great and also illustrates how frivolous and completely damaging design review is for housing in our city

30.09.2025 17:02 β€” πŸ‘ 11    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Thank you for posting, this has been such a weird gap in the street on Mercer. What a senseless saga of housing

01.10.2025 03:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Explaining #seattle housing politics to a New Yorker is hilarious. nimby position is new buildings only downtown. The far left most yimby position is brownstone height buildings near commercial centers. The notion of brownstone height everywhere or some taller buildings is outside polite discourse.

30.09.2025 05:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Having often dealt with the frustration of binder-limited projects, we sought a more accessible source for nanobodies than yeast display or llama. Here we introduce Germinal, computationally designing antibody-like binders with such a hit rate that only tens need to be screened for each target.

24.09.2025 16:32 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

I’d buy a sign! Feels strange to only see the nimby signs around

08.09.2025 05:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Is there an opposing group β€œQueen Anne for more neighbors” or β€œQueen Anne for the people”?

07.09.2025 05:21 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Ladder streets - Wikipedia

One of the densest places in the world has ladder streets. Seems doable in QA. en.wikipedia.org/wiki/Ladder_...

07.09.2025 05:18 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Exclusive: Famed protein structure competition nears end as NIH grant money runs out Agency silent on funding renewal for contest that inspired creation of AIs that predicted how proteins would fold

Speak up to prevent a major loss for the field. CASP, which helped shaping structural biology including AlphaFold is on the verge of shutting down. NIH funding has lapsed, UC Davis support ends and the core team is being let go. Painfully shortsighted.

04.07.2025 12:06 β€” πŸ‘ 63    πŸ” 45    πŸ’¬ 0    πŸ“Œ 3
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50 Reasons Why Everyone Should Want More Walkable Streets From making you live longer to making cities more resilient: If you want a reason to make your city more walkable, it's in here.

β€œSomeone with a 1-hr car commute needs to earn 40% more to be as happy as someone with a short walk to work. On the other hand, if someone shifts from a long commute to a walk, their happiness increases as much as if they’d fallen in love.” #CityMakingMath

50 reasons to want more walkable cities.

26.06.2025 14:12 β€” πŸ‘ 758    πŸ” 241    πŸ’¬ 21    πŸ“Œ 23

Job Garcia’s kidnapping by the Trump administration is the top story on the LA Times website right now.

www.latimes.com/california/s...

21.06.2025 06:07 β€” πŸ‘ 6204    πŸ” 2591    πŸ’¬ 66    πŸ“Œ 81

One of the hardest things about growing up in #nyc and living elsewhere is the utter lack of Chinese Cuban restaurants #iykyk… Trader Joe’s plantains scratch that itch

16.06.2025 02:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Excited to announce that Pramila Jayapal will be our featured speaker at the Rally before the JUNE 14th - Seattle NO KINGS MARCH.

#nokings #DefendDemocracy #FightAuthoritarians #NoFascism

10.06.2025 03:01 β€” πŸ‘ 414    πŸ” 68    πŸ’¬ 9    πŸ“Œ 4
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#seattle

14.06.2025 19:23 β€” πŸ‘ 1745    πŸ” 318    πŸ’¬ 10    πŸ“Œ 12
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Investigate federal vaccine panel's overhaul, AMA urges Senate Health and Human Services Secretary Robert F. Kennedy Jr., a longtime skeptic of vaccinations, said he ousted the CDC committee to restore "public trust in vaccines."

THE AMERICAN MEDICAL ASSOCIATION CALLS FOR A SENATE INVESTIGATION INTO RFK, JR.

"The resolution’s sponsor, Dr. Jason Goldman, urged his colleagues to support the request for an investigation to ensure the AMA is not β€œon the wrong side of history.”

chicago.suntimes.com/health/2025/...

13.06.2025 02:13 β€” πŸ‘ 3392    πŸ” 1064    πŸ’¬ 104    πŸ“Œ 49
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Opinion | Elon Musk’s Legacy Is Disease, Starvation and Death

"If there were justice in the world, Musk would never be able to repair his reputation, at least not without devoting the bulk of his fortune to easing the misery he’s engendered."

www.nytimes.com/2025/05/30/o...

31.05.2025 03:32 β€” πŸ‘ 140    πŸ” 43    πŸ’¬ 4    πŸ“Œ 4

Temporary, but a clear win for HB1110 legal approach! Little fanfare is ideal really, when tensions run so high

29.05.2025 15:10 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Trump Pardoned Tax Cheat After Mother Attended $1 Million Dinner

This guy stole $10 million from the employees of his nursing home to buy himself a luxury yacht and Cartier watches. He PLED GUILTY.

And because his Mom gave Trump $1 million, he just got a pardon.

And this story barely makes the news today. WTF. www.nytimes.com/2025/05/27/u...

28.05.2025 00:14 β€” πŸ‘ 11222    πŸ” 5214    πŸ’¬ 701    πŸ“Œ 384

Interest rates too high? And new β€œuncertainty”

28.05.2025 01:18 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Autoimmune Disease, Transformed?

'(...) we could end up with completely new treatments for some of these conditions (or for subsets of patients therein), but no matter what we're going to learn a tremendous amount about the role of B cells in their etiologies, from several different angles all at once'
@dereklowe.bsky.social

27.05.2025 04:32 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

I think this is the most hyper local bluesky interaction I’ve had, bluesky lives!

27.05.2025 02:02 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

So they are not closing? I hope not. Also my neighborhood coffee, and really great cookies and coffee cake and pocha

26.05.2025 04:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Nucleate Seattle: 2025 Demo Day Β· Luma Please join Nucleate Seattle in celebrating our 2025 Activator cohort at our Demo Day! We invite all biotech and bio-entrepreneurial enthusiasts of all stages…

Cyrus's CEO, Lucas Nivon, is the keynote speaker for Nucleate Seattle’s Activator Demo Day! Join us to hear him speak about Life Sciences Commercialization on May 14th at the Allen Institute. #Seattle #Biotech #Innovation lu.ma/18yj2jg3?tk=...

13.05.2025 20:33 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Good idea to try! We have been testing deep research against review papers it can’t access and been impressed by low error rate and ability to update w more recent data. I was a skeptic but those tests were convincing

11.05.2025 05:43 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The structure of human sweetness: Cell
Sweet receptor bound to two widely used artificial sweeteners: sucralose and aspartame. A single receptor that mediates all our responses to sweet-tasting compounds.

08.05.2025 18:05 β€” πŸ‘ 28    πŸ” 9    πŸ’¬ 3    πŸ“Œ 0

Thanks for attending! My neighbors in upper QA are incensed by the changes. Apartments are just terrible to them. And I’m too busy to attend meetings w retirees

08.05.2025 03:00 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Exclusive: NSF stops awarding new grants and funding existing ones US science funder also plans to screen grant applications for compliance with β€˜agency priorities’.

Nature reports that the National Science Foundation has stopped awarding new grants and allotting funds to existing ones. All of them. @colincarlson.bsky.social says that unless the freeze is lifted, it β€œis going to destroy people's labs.” 2/10
www.nature.com/articles/d41...

01.05.2025 23:50 β€” πŸ‘ 709    πŸ” 445    πŸ’¬ 16    πŸ“Œ 58

Not just more data but also more types of data about tissues and cells.

22.04.2025 15:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Great piece. Often try to explain this to tech people, they train on human data, it is often easily observable. In bio much of data is invisible to us, now we have transcriptomics, spatial bio, etc. Hubble telescope is an example, before that you can’t see so far! We need bio Hubbles

22.04.2025 15:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

So happy @openfold.io is growing! More exciting announcements coming soon about our new all atom model adding ligand and RNA/DNA

15.04.2025 15:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I’d never even heard of this species of NIMBY before until last few weeks, then read about it in Abundance

08.04.2025 03:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@lucasnivon is following 20 prominent accounts