@kurakulabmsm.bsky.social
Molecular Life History Lab led by Shigehiro Kuraku at National Institute of Genetics in Mishima, Japan. Home of Squalomix & MedakaBase フィールド&分子生物学実験寄り動物ゲノム情報学&分子進化学研究とリテラシー普及@遺伝研
New chapter of sex determination, with sharks and rays!
Our study, utilizing embryonic samples from cooperative aquariums, revealed the ancient sex chromosome origin and unique sex determination potentials.
Published today in PNAS
www.pnas.org/doi/full/10....
#Squalomix
\ ⏰まだまだ参加募集中 /
三島市内小学生のみなさま、遺伝研でお待ちしています！！
Very curious to follow up how the taxa of our interests, particularly Chondrichthyes 🦈, of course, are catalogued under this 'Tree of Sex Consortium' relaunched.
01.07.2025 13:22 — 👍 2 🔁 0 💬 1 📌 0
Ready for Satellite Symposium at Okinawa Churaumi Aquarium, our long-term scientific partner,
after fruitful days at #ipfc12 in Taipei 🇹🇼.
先週台北で開かれたアジア・パシフィック魚類会議のサテライト研究会が沖縄美ら海水族館で本日開催されます。当研究室が進めてきた、深海適応の分子メカニズムを含むサメ・エイ類のゲノム進化学研究についてその場で紹介します。
ご興味おありでしたら、 #Squalomix で検索ください。
#ERGAReads | Can #genomic analysis estimate past population size? ⌛️📉
Sequentially Markovian coalescent #SMC methods can lead to misleading estimates. Cross-disciplinary collaboration is needed to interpret them accurately. 🧬
🔗 Read more: www.cell.com/trends/genet... @qmul.ac.uk
#ERGAReads | This week, we highlight Squalomix, our newest associated partner 🦈🧬 #Squalomix tackles key challenges in #elasmobranch genomics through advanced cytological techniques and high-fidelity long-read sequencing.
🔗 f1000research.com/articles/11-...
@kurakulabmsm.bsky.social #sharks #rays
New preprint from #Squalomix
www.biorxiv.org/content/10.1...
Towards bona fide 'whole-genome' analysis encompassing rDNA, tRNA, histones, centromere, elusive HoxC , ... , while featuring genome size change like shown here for the V2R clusters.
@ebpgenome.bsky.social @ergabiodiv.bsky.social
We have extended our abstract submission to June 1st! Get conference details here: www.baskingshark.ie/conference2025
and submit your abstract here: docs.google.com/forms/d/e/1F...
GRCz12tu is available on Genbank. This will be one of two genomes that will be considered "reference" genomes, there will also be a GRCz12ab assembly coming. It has entered the NCBI annotation pipeline and will also go into the Ensembl annotation pipeline.
www.ncbi.nlm.nih.gov/datasets/gen...
(3/4) 🌍 The EBP dream-team are sequencing genomes 🧬 to accelerate #research, improve protections, and identify the species that make up critical ecosystems.
🧬Dive into these genomes with @kurakulabmsm.bsky.social, @ergabiodiv.bsky.social, @vertebrategenomes.bsky.social, and many more 🌏
We are based at National Institute of Genetics in Mishima, Japan, close to Suruga Bay >2500m deep & Mt. Fuji >3700m high.
#Squalomix #MedakaBase
Empowering medaka fish biology with versatile genomic resources in MedakaBase https://www.biorxiv.org/content/10.1101/2025.05.13.653297v1
16.05.2025 10:34 — 👍 2 🔁 1 💬 0 📌 1RepeatMasker 4.1.9 released. This release includes fixes for ProcessRepeats (speed issues, and divide-by-zero), a
fix for clade-level pHMM (nhmmer) searches, and some minor utility/documentation updates. See the www.repeatmasker.org for more release details.
Figure 1. Genomic and epigenetic features contributing to and resulting from the intragenomic heterogeneity of mutations. The genomic regions shown in red and cyan indicate the genomic compartments with the intragenomic heterogeneity.
“Intragenomic mutational heterogeneity: structural and functional insights from gene evolution”
by Yuichiro Hara & Shigehiro Kuraku (@kurakulabmsm.bsky.social)
FREE access till June 24th at this link:
authors.elsevier.com/a/1l2K3cQbJF...
Our research on sharks and rays conducted in National Institute of Genetics, Japan, at the foot of Mt Fuji has just been introduced at #PacBioPRISM.
#Squalomix
Lab HP www.nig.ac.jp/nig/research...
Learn about the internationally-diverse Phng Lab @riken-bdr.bsky.social 🇲🇾 🇦🇺 🇯🇵 🇨🇳 🇺🇦 🇲🇲 🇮🇳 🐟 #zebrafish @phnglab.bsky.social
14.04.2025 09:19 — 👍 5 🔁 1 💬 0 📌 0Having a glimpse of the Vietnam's Red List, with the same mind about biodiversity and potentials of genomics as we tackle with the Japanese counterpart.
vast.gov.vn/web/vietnam-...
#PacBioPRISM
One week to go!
#PacBioPrism
#Squalomix
Our research on sharks🦈 & rays will be introduced at #PacBioPrism in Da Nan, Vietnam🇻🇳, on April 15 by Shigehiro Kuraku.
#Squalomix
昨日の一般公開、当研究室は、DNA情報に基づいて脊椎動物の進化を辿る研究の意義や手法、とくにサメやエイの貴重な試料の確保について紹介しました。たくさんの方々に来場いただき、さまざまな刺激をいただきました。
www.sut-tv.com/news/single/...
#遺伝研一般公開
#Squalomix
Our research on sharks🦈 & rays will be introduced at #PacBioPrism in Da Nan, Vietnam🇻🇳, on April 15 by Shigehiro Kuraku.
#Squalomix
Presenting our activity in June at Joint Conf. of Asian Society of Ichthyologists (ASI) Annual Meeting & Indo-Pacific Fish Conf. (IPFC) in Taipei 🇹🇼
Title 'Unraveling shark and ray evolution through genomic exploration' by Shigehiro Kuraku @sighex
#IPFC12 #IPFC2025 #ASI2025
RepeatMasker 4.1.8 released. A major update to ProcessRepeats has significantly reduced RepeatMasker's memory requirements. Additionally, RepeatMasker now supports the new FamDB 2.0.0 format introduced in Dfam 3.9. See the www.repeatmasker.org for more release details.
13.03.2025 00:13 — 👍 7 🔁 5 💬 0 📌 0
Eggcase of the zebra shark (aka leopard shark), Stegostoma tigrinum.
24.02.2025 12:09 — 👍 1 🔁 2 💬 0 📌 0
Figures from our review paper - Genomic reconsideration of fish non-monophyly: why cannot we simply call them all ‘fish’?
link.springer.com/article/10.1...
