Understanding the neuroimmune regulation of innate immunity | Supervisor Connect
๐ PhD positions available @MonashUni
Join our lab to explore how neurons and immune cells shape gut immunity!
๐งฌ Single-cell RNAseq
๐ฌ 3D imaging
๐ง Neuro-immune interactions
๐ฅ Great mentoring & collaborations
Apply now ๐ tinyurl.com/Seilletlab
02.06.2025 06:59 โ ๐ 8 ๐ 10 ๐ฌ 0 ๐ 0
Innate lymphoid cells 3 (ILC3s) are a subset of immune cells that are critical to gut immunity.โฏWhen there is excess fat, such as after a rich meal, ILC3s store this fat in tiny lipid droplets to maintain their function. In this 3D illustration, we can see a lipid droplet (in orange) inside an ILC3.
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health.
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
19.05.2025 01:41 โ ๐ 9 ๐ 6 ๐ฌ 0 ๐ 1
JCI -
A dominant-negative IFNGR1 variant reveals broad immune cell sequestering of IFN-ฮณ
๐จ New publication alert! ๐จ
Thrilled to share our latest research out today in @jclinical-invest.bsky.social! This work is another great outcome of my amazing clinical research partnership with first author Samantha Chan and RMH. @wehi-research.bsky.social #immunology #research #JCI
15.04.2025 23:34 โ ๐ 8 ๐ 3 ๐ฌ 1 ๐ 1
Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com
@wehi-research.bsky.social @benjbroom.bsky.social
08.05.2025 23:31 โ ๐ 31 ๐ 7 ๐ฌ 0 ๐ 0
A visualisation of immune cells, with headline "Long-lasting vaccines of the future a step closer"
Future vaccines a step closer. Research from @groomlab.bsky.social, @benjbroom.bsky.social and team use novel approach and mRNA tech to boost stem cell-like memory CD8+ T cells after vaccination.
Published in @jem.org
www.wehi.edu.au/news/vaccine...
07.05.2025 23:51 โ ๐ 30 ๐ 8 ๐ฌ 1 ๐ 2
Our May issue is here! rupress.org/jem/issue/22...
Cleary et al. (doi.org/10.1084/jem....) developed a new intravital technique for imaging pulmonary lymphatics. The cover depicts a 3D projection of a whole lung lobe with lymphatics (purple) and smooth muscle (white) labeled.
05.05.2025 14:49 โ ๐ 8 ๐ 3 ๐ฌ 0 ๐ 2
@benjbroom.bsky.social et al. @groomlab.bsky.social show that transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection. rupress.org/jem/article/...
๐ In JEM #Immunology Collection: rupress.org/jem/collecti...
#AAI2025
30.04.2025 20:15 โ ๐ 4 ๐ 2 ๐ฌ 0 ๐ 0
This year's JEM #Immunology collection highlights recent findings in the field of B cells, CD8+ T cell stemness, priming and differentiation, CD4+ T cell heterogeneity, autoimmunity, lymphatic immunophysiology and innate immune signaling. ๐ rupress.org/jem/collecti...
#AAI2025
29.04.2025 14:15 โ ๐ 18 ๐ 7 ๐ฌ 0 ๐ 1
Thrilled to share our work now published on @cp-immunity.bsky.social . Big thanks to our collaborators. Here we show that short-term High-Fat diet impairs ILC3 functions in producing IL-22 through microbiota-dependent and-independent mechanisms.
15.04.2025 01:25 โ ๐ 14 ๐ 9 ๐ฌ 1 ๐ 3
Youโre invited! Celebrate the Day of Immunology at WEHI on 29 April.
๐นHear from top scientists
๐นDiscover the new Snow Centre for Immune Health
๐นGo behind the scenes with a lab tour
๐นEnjoy morning tea & meet the team
Register now - www.immunology.org.au/events/-ASI-...
10.04.2025 00:44 โ ๐ 2 ๐ 2 ๐ฌ 0 ๐ 0
Happy one week of my @jem.org paper!
Our work from the @groomlab.bsky.social at @wehi-research.bsky.social identifies using early IFN-I blockade alongside mRNA vaccination to direct CD8+ T cell positioning in the lymph node to drive Tscm cell differentiation and enhance vaccine protection
17.03.2025 10:42 โ ๐ 22 ๐ 6 ๐ฌ 1 ๐ 0
Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection | Journal of Experimental Medicine | Rockefeller University Press
Broomfield et al. demonstrate that early type I interferon blockade alters CXCR3 chemokine regulation and cell location to promote an antigen-dependent CD8
#WeekendRead! #InterferonFriendOrFoe!
@benjbroom.bsky.social @groomlab.bsky.social &co show @jem.org that transient type I IFN inhibition upon LCMV infection or a mRNA vaccine boosts stem-like memory CD8 T cells by altering their location within the draining lymph node, potentiating virus protection
15.03.2025 15:03 โ ๐ 13 ๐ 4 ๐ฌ 0 ๐ 0
Very excited our work out in @jem.org โTransient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protectionโ
@wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social
Thread below.
11.03.2025 03:26 โ ๐ 54 ๐ 21 ๐ฌ 2 ๐ 3
@benjbroom.bsky.social et al. @groomlab.bsky.social show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cellโlike memory CD8+ T cells rupress.org/jem/article/...
10.03.2025 16:18 โ ๐ 26 ๐ 10 ๐ฌ 0 ๐ 3
So lucky to be in a lab that does great science AND indulges in a weird photoshoot ๐ซถ
Happy holidays!
19.12.2024 06:54 โ ๐ 8 ๐ 1 ๐ฌ 2 ๐ 0
๐จ๐ฆ in ๐ฆ๐บ Scientist. Geek. Feminist. She/her. Lab head (viralvaxlab.com) at the Doherty Institute and University of Melbourne, interested in all things CD4/TFH/vaccine and virus-related. I stare at dots a lot.
Immunologist at John Curtin School of Medical Research, Australian National University๏ผ
https://scholar.google.com.au/citations?user=FQ61D_8AAAAJ&hl=en&authuser=1
Australian Nobel Laureate (Medicine 1996) know for discoveries re immune surveillance & viral immunity. As a science communicator he also advocates aggressive action re climate change & sustainability & has published 7 'lay' books on science.
Associate Professor at Harvard Medical School, in love with a red-haired beautiful woman, his kids... and immunology. He/him/his. ๐ฎ๐น ๐บ๐ธ Views my own.
Immunologist & Group Leader at the Peter MacCallum Cancer Centre. Views are my own.
https://www.petermac.org/research/research-programs-and-labs/cancer-immunology-program/ian-parish-lab
Immunologist.
Head of Dendritic Cell biology lab, Monash Uni, Australia.
Interests: innate immunity, IFN biology
Immune cell recruitment, glycocalyx, chemokines and extracellular matrix at the Manchester Centre for Cell Matrix research and Lydia Becker Institute for Immunology he/him
https://www.wellcome-matrix.org/people/doug-dyer/
#glycotime
Scientific Editor at Journal of Experimental Medicine @jem.org @rupress.org. Interested in T cell biology, mucosal immunology, and cancer immunology
Immunologist/professor interested in viral and mycobacterial lung infectious diseases. Family man. Bike rider. Storm & train chaser. You're going to get a lot of exposure to science, art, photography, weather, and bikes on this feed. My opinions are Mine.
Assistant Professor at Johns Hopkins Bloomberg School of Public health using #vaccinology to better understand human #immunology and #immunometabolism
CCV Postdoctoral Fellow @wehi-research.bsky.social; interested in the cellular origins of liver cancer; President of the 2025 WEHI Postdoctoral Association
๐ฒ๐พ scientist in ๐ฆ๐บ | ๐ฆ ๐ฉธ #malaria |๐ฆ #nanobodies | Prof @WEHI_research @ourANU | on Wurundjeri, Ngunnawal & Ngambri lands | views my own ๐๐ปโโ๏ธ ๐
Creating a more equitable world through better health.
Australiaโs largest child health research institute | Top 3 globally for paediatric research impact
Transforming child and adolescent health through world-class science, clinical innovation & global collaboration.
1,800+ researchers | Based in Melbourne
Senior Postdoc in the Feltham Lab @ WEHI, Australia. A bit in academia, a bit in industry, a lot in targeted protein degradation. Bouldering, dogs, blue hair.
The Peter Doherty Institute for Infection and Immunity is a joint-venture between The University of Melbourne and The Royal Melbourne Hospital. Research includes #HIV, #hepatitis, #malaria, #influenza #COVID19 & more.
www.doherty.edu.au
Journal of Experimental Medicine publishes immunology, cancer, stem cells, microbial pathogenesis, vascular biology, and neurobiology research. Published by Rockefeller University Press @rupress.org
๐ rupress.org/jem
