@bjohnstone.bsky.social
Structural biologist and coffee-fuelled research fellow in the Ghosal Lab at Bio21Institute, University of Melbourne
As a big fan and sometimes baker of science-themed cakes, this is amazing Rosie! 😍 Perfect way to honour an exciting Nobel Prize!
09.10.2025 22:23 — 👍 4 🔁 0 💬 1 📌 0
Seminar time⏲️ We welcome Professor Dimitrios Fotiadis, IBMM, Medical Faculty, University of Bern: “Structural and mechanistic insights into transmembrane glucose transport and light-driven proton pumping” 🥳More info: ccemmp.org/events/ccemm...
11.08.2025 03:13 — 👍 1 🔁 1 💬 0 📌 0
Join our Cryo-ET workshop and learn sample preparation, grid screening and data collection.
📍Ian Holmes Imaging Centre
🗓️9th-10th September 2025
🔗Register now: rduevents.unimelb.edu.au/event/2271-c...
#CryoET #ElectronMicroscopy #StructuralBiology #CCeMMP
An image of a large diamond crystal structure model with a large sign on the top of it
A group of people sat around the giant diamond structure
detail of someone putting together the giant diamond structure
Many in the #Crystallography community will remember this (and may have helped put part of it together). Our record breaking diamond structure built at the 2023 IUCr congress in Melbourne
[Photo credit Jun Aishima]
Congratulations Javaid!
06.06.2025 09:10 — 👍 0 🔁 0 💬 1 📌 0Cryo-EM was conducted at Ian Holmes Imaging Centre at, with data collected by Hamish Brown, with contributions from
@bio21director.bsky.social , @bigfrenchman.bsky.social
, Michelle Christie, Riya Joesph, Craig Morton and Rod Tweten and team. #cryoEM
This work was part of my PhD at UniMelb and was my first foray into cryo-EM! Admittedly, learning the various steps of cryo-EM on proteoliposome samples felt like jumping in the deep end so I am very happy and proud for all to see how it worked out.
30.03.2025 10:50 — 👍 1 🔁 0 💬 1 📌 0
These structures reveal how multiple regulatory features, such as proteolytic activation, ensure pore formation. Furthermore, we find features that are not common to the related CDC family of pore-forming toxins. Instead, CDCLs seem show features that straddle the CDC, MACPF and gasdermin families.
30.03.2025 10:50 — 👍 0 🔁 0 💬 1 📌 0
This includes the crystal structure of the proteolytically-activated form and cryo-EM structures of the inserted pore and prepore-like complex, solved on the surface of liposomes.
30.03.2025 10:50 — 👍 2 🔁 0 💬 1 📌 0
Excited to share that our work on a family of pore-forming proteins is now live in Science Advances! We show structural snapshots across the entire pore-forming pathway for a cholesterol-dependent cytolysin-like (CDCL) bicomponent system.
30.03.2025 10:50 — 👍 32 🔁 9 💬 3 📌 0Our paper on the structure and evolution of baculovirus is out! Excited to share work I did at Monash in the Coulibaly lab, with big shout outs to co-authors Josh and Jungmin, collaborators Mart and team and everyone else who contributed. Definitely one of the coolest structures I'll ever work on 🤩
24.12.2024 01:16 — 👍 23 🔁 4 💬 0 📌 0
