CalcinottoLab

Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition - Nature Communications Tumor-associated neutrophils exhibit heterogeneity in breast cancer. Here, the authors identify a distinct precursor population (PreNeu) in estrogen receptor-positive tumors. PreNeu suppress homologou...

🚀 Excited to share our latest publication!
👉 www.nature.com/articles/s41...
A fantastic collaboration with an incredible team.

#BreastCancer #Neutrophils #TumorMicroenvironment #PARPinhibitors #DNARepair #NatureCommunications #CancerImmunology #CalcinottoLab

Join us for the session “DNA Repair and Immunosurveillance” at #EACR2025, where I’ll be giving a talk on neutrophils and synthetic lethality in breast cancer”

Senescent neutrophils: a hidden role in cancer progression Neutrophils have recently received increased attention in cancer because they contribute to all stages of cancer. Neutrophils are so far considered to have a short half-life. However, a growing body o...

Senescent neutrophils: a hidden role in cancer progression: Trends in Cell Biology www.cell.com/trends/cell-...

Getting ready to start!
Join us for this session #AACR2025 where I will be speaking alongside Nicky McGranahan and Ronny Drapkin.
Looking forward to an exciting discussion on how immunology shapes cancer initiation!
1:00 p.m. - 2:30 p.m. — see you there!

Thrilled to share that our group will be presenting at a major symposium at the AACR Annual Meeting in Chicago this Sunday!

Catch us at AACR—Chicago, we’re ready!
#AACR25 #CancerResearch #Immunology #SomaticEvolution #EarlyDetection #CancerBiology #TeamScience #SeeYouInChicago

Bellinzona is ready to host the next SYIS seminar on April 17!
I’m excited to join the event as a speaker, alongside Christian Pasquali from OM Pharma.
Join us at 5:00 pm (CET) — either in person in Bellinzona or online via Zoom!

Senescent neutrophils: a hidden role in cancer progression - PubMed Neutrophils have recently received increased attention in cancer because they contribute to all stages of cancer. Neutrophils are so far considered to have a short half-life. However, a growing body o...

Thrilled to share our new review published by @cp-trendscellbio.bsky.social
In this article, my lab explores the heterogeneity of cancer neutrophils and discusses their implications in both cancer progression and therapy resistance. Check out the full review here:
pubmed.ncbi.nlm.nih.gov/39362804/