Bidirectional histone monoaminylation dynamics regulate neural rhythmicity - Nature
TG2 functions as an eraser and exchanger of H3 monoaminylations, including histaminylation of Gln5 of histone H3.
Excited to see our paper out @nature.com In this work, we discovered that histone monoaminylation dynamics are regulated by a single enzyme (TGM2) and can promote neural rhythmicity by inhibiting the binding of WDR5 to H3 N-terminus.
www.nature.com/articles/s41...
10.01.2025 04:06 — 👍 1 🔁 0 💬 0 📌 0
jobrxiv.org/job/purdue-u...
02.12.2024 13:39 — 👍 0 🔁 0 💬 0 📌 0
pH-Controlled chemoselective rapid azo-coupling reaction (CRACR) enables global profiling of serotonylation proteome in cancer cells
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
Although serotonylation was discovered in the 1950s, a full picture of serotonylated proteins in cells is poorly understood. In this work, we applied pH-controlled CRACR (originally developed by @achemsynbio.bsky.social lab) for profiling serotonylation proteome. www.biorxiv.org/content/10.1...
15.05.2024 03:53 — 👍 3 🔁 0 💬 0 📌 0
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Chemical Biologist. Tenure track assistant prof @EPFL. Trying to make sense of the world by changing one variable at a time. https://www.epfl.ch/labs/libn/
Structural biology and Biophysics at the University of Nottingham and Research Complex at Harwell (UK).
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He/him.
Geochemist and biologist, Interested in lipids, RNA, pathogens, & synthesis of life.
Chemical Biologist - Postdoc with Yael David - interested in nucleic acids and sometimes in proteins-
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Studying genomics, machine learning, and fruit. My code is like our genomes -- most of it is junk.
Guest Scientist IMP Vienna, Board of Directors NumFOCUS
Incoming Prof UMass Chan Medical
Previously Stanford Genetics, UW CSE.
MPI for Multidisciplinary Sciences
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nucleic acids chemical biologist
York University 🇨🇦
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Assistant Professor in Organic Chemistry 🧪🧬 at Universitat de Barcelona @ub.edu and Beatriz Galindo Researcher 🧫💫 @cienciagob.bsky.social
Researcher in Chemical Biology, Professor at LMU Munich
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Chemist using enzymes to build molecules. Chemo-enzymatic synthesis of modified nucleotides and investigation of modified mRNAs and other nucleic acids. Permanent scientist at the University of Münster, Germany. PhD from RentmeisterLab.
Chemical biologist at Stanford with a love for covalent binding molecules and hydrolases.
