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Xiao Fu

@xiaofu90.bsky.social

We develop diverse computational approaches to study tumour organisation and dynamics at the Cancer Research UK Scotland Institute @cruk-si.bsky.social

212 Followers  |  199 Following  |  6 Posts  |  Joined: 19.11.2024  |  1.9902

Latest posts by xiaofu90.bsky.social on Bluesky

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Pre-Cancer Immunology The Pre-Cancer Immunology Lab (James Reading Lab) is mapping pre-invasive T cell dynamics during carcinogenesis to detect and intercept cancer development.

🚨 PhD Position available in our lab 🚨 exploring the power of blood immune multi-omics to detect lung cancer years prior to clinical diagnosis in a unique cohort of >10,000 CT screened individuals.
βœ… Wet & dry lab
βœ… September 2025 enrolment
βœ… UK tuition fees only

www.ucl.ac.uk/medical-scie...

05.08.2025 17:57 β€” πŸ‘ 8    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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We are hiring an #ExecutiveAssistant to support our new Institute Director, Prof Samra Turajlić

Apply online today at: apps.cruk.manchester.ac.uk/recruitment/...

Starting Salary: Circa Β£40,000 per annum
Closing Date: 28/08/2025
Duration of Post: Permanent
Job Ref: MI/25/44

04.08.2025 12:32 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 2
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Group Leader – Molecular Systems Biology Unit Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...

Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!

30.07.2025 15:14 β€” πŸ‘ 71    πŸ” 78    πŸ’¬ 1    πŸ“Œ 1
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Associate or Senior Editor, Nature Biomedical Engineering Job Title: Associate or Senior Editor, Nature Biomedical Engineering Organization: Nature Portfolio Location: New York, Jersey City, Shanghai or Beijing – Hybrid Working Closing date: August 20, 2025 ...

My colleagues at Nature Biomedical Engineering @natbiomedeng.nature.com are hiring an associate or senior editor. Ideal applicant will have expertise in immunology, immunotherapy, or immuno-oncology.

Please feel to ask me questions!

springernature.wd3.myworkdayjobs.com/SpringerNatu...

30.07.2025 18:21 β€” πŸ‘ 24    πŸ” 24    πŸ’¬ 0    πŸ“Œ 0

Excited for this @cp-cell.bsky.social article co-led by @fertiglab.bsky.social and Genevieve Stein-O'Brien, on creating a plain language "grammar" to easily write simulation models as virtual laboratories for complex systems like cancer.

Fully open access and open source! πŸ§ͺ #mathonco #mathbio

29.07.2025 01:06 β€” πŸ‘ 25    πŸ” 13    πŸ’¬ 2    πŸ“Œ 0
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Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships - Nature Biomedical Engineering A method integrates perturbation mapping with 10X Visium spatial transcriptomics to map tumour genetic complexity and heterogeneity.

This is a great set of methods for studying combinatorial effects of cancer mutations on spatial phenotypes.

Clever experimental design by @breinigmarco.bsky.social hijacking Visium and elegant analysis by @lomakinai.bsky.social and @elihei.bsky.social

www.nature.com/articles/s41...

29.07.2025 05:51 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Beautiful work!! Many congratulations, @mathcancer.bsky.social @fertiglab.bsky.social and all authors!!

28.07.2025 15:05 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories We developed a plain text modeling languageβ€”a cell behavior hypothesis grammarβ€”to easily build virtual cell models and connect them to data, helping scientists to unlock the hidden dynamics of tissues...

Really excited to share our new @cellpress.bsky.social Cell paper with @fertiglab.bsky.social and colleagues. 1/n

www.cell.com/cell/fulltex...

@jktgfoundation.bsky.social @itcrtraining.bsky.social @smbmathbiology.bsky.social #mathbio #mathonco @mathonco.bsky.social @deniswirtz.bsky.social

28.07.2025 14:20 β€” πŸ‘ 52    πŸ” 20    πŸ’¬ 3    πŸ“Œ 3
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Postdoctoral Research Associate at Queen Mary University of London Discover Postdoctoral Research Associate jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.

We are looking for a postdoctoral researcher to investigate the role of inflammation on therapy resistance in colorectal cancer using patient-derived organoids and single-cell multiomics. Please reach out if interested:
www.jobs.ac.uk/job/DNX776/p...

28.07.2025 07:58 β€” πŸ‘ 2    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

✨Thrilled to announce an exciting opportunity to work on our project exploring WNT-driven cell competition as a novel preventative strategy in CRC 🧬

We’re hiring a Senior Scientific Officer to join me in @owen_sansom’s lab. Great science and lots of room to make an impact! πŸ‘©πŸ½β€πŸ”¬

25.07.2025 22:51 β€” πŸ‘ 6    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1
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Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes | EMBO reports imageimageMetastatic primary tumours upregulate Upp1 in neutrophils, which elevates circulating uracil. UPP1-expressing neutrophils accumulate in the lung where they inhibit CD8+ T cells, promote fibr...

Delighted to share that our work β€œUridine Phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes” was published today in @emboreports.org, describing how neutrophil metabolism influences niche priming to support metastasis (1/14) www.embopress.org/doi/full/10....

23.07.2025 20:50 β€” πŸ‘ 22    πŸ” 13    πŸ’¬ 2    πŸ“Œ 2
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Great news! The AACR journals are now on BlueSky! Be sure to follow @aacrjournals.bsky.social!! #FollowFriday

18.07.2025 19:59 β€” πŸ‘ 38    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
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Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.

As a new postdoc in my lab (@cshlnews.bsky.social β†’ @jhu.edu) @adrover.bsky.social (now @crick.ac.uk) saw NETs in tumorsβ€”I shrugged. But he looked closer in 3D: NETs block tumor vessels, driving necrosis, hypoxia, EMT & metastasis.
πŸ”— www.nature.com/articles/s41...
@jhu-bdps.bsky.social @nature.com

17.07.2025 19:26 β€” πŸ‘ 36    πŸ” 10    πŸ’¬ 0    πŸ“Œ 1
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Genome doubling fuels ovarian cancer evolution and immune dysregulation Single-cell analysis reveals the extent of genome doubling in ovarian cancer, its variability and its role in enabling tumours to evade the immune system.

Single-cell analysis reveals the extent of genome doubling in ovarian cancer, its variability and its role in enabling tumours to evade the immune system

go.nature.com/4kJLAjZ

17.07.2025 08:14 β€” πŸ‘ 19    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
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Mathematical modelling of cancer cell evolution and plasticity In this review, we argue that mathematical modelling is an essential tool for understanding cancer cell evolution and phenotypic plasticity. We show t…

New review from @chloecolson.bsky.social on cancer evolution & plasticity from a mathematical modelling lens: www.sciencedirect.com/science/arti...

Chloe provides a framework to think about plasticity & evolution, & explains how maths models can reveal cell dynamics that we can't directly observe.

10.07.2025 13:42 β€” πŸ‘ 23    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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πŸ“£ ERC Synergy Grant 2026 call for proposals is now open!

Application deadline 5 November 2025.

πŸ“ Groups of 2-4 researchers
πŸ“ Jointly addressing ambitious problems & with different skills

Application portal πŸ‘‰ europa.eu/!XpwptY
General info πŸ‘‰ europa.eu/!PR6gt8

#ERCSyG #FrontierResearch

10.07.2025 14:47 β€” πŸ‘ 31    πŸ” 20    πŸ’¬ 1    πŸ“Œ 2
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Can using synthetic approaches to build biology help teach us the design principles of how embryos build themselves? πŸ‘·β€β™€οΈπŸ”§

If this is a question that interests you, come and share your thoughts at this Royal Society Workshop on Generative Biology

royalsociety.org/science-even...

03.07.2025 16:25 β€” πŸ‘ 36    πŸ” 20    πŸ’¬ 1    πŸ“Œ 1
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UK cancer breakthrough as simple blood test could help pinpoint treatment EXCLUSIVE: Skin cancers can be among the most aggressive forms of the disease so using drugs to shrink them must be used with precision.

Mathematical models and ctdna have reached the clinic - the ultimate personalised trial testing adaptive targeted therapy highlighted in the news today!
#EBEcancer25

www.express.co.uk/life-style/h...

02.07.2025 17:29 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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πŸ“’Save the date for our upcoming Immunology Workshop - 'Lessons from the microbes within us; developing next generation immunotherapies'

πŸ“…23-24 October 2025

πŸ“CRUK Scotland Institute, Glasgow

πŸ”—To find out more, visit our website: www.crukscotlandinstitute.ac.uk/immuno_workshop_2025

02.07.2025 15:49 β€” πŸ‘ 2    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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🚨 Meet Sarah, Vice-Chair of the FEBS-IUBMB-ENABLE Conference!
πŸ—“οΈ September 2025
🎟️ Early bird deadline: end of June!

βœ… Scientific talks
βœ… Career workshops
βœ… A chance to present YOUR research

πŸ”— More info & registration: febs-iubmb-enableconference.org
#PhDlife #LifeSciences #Conference #Glasgow2025

26.06.2025 16:03 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

- A postdoc to work on cancer extravasation (4-year project).
- A postdoc help in completing Filopodia-related lab projects (2-year).
- Multiple Marie Curie postdoc positions that will open in the fall.
- We will open a 5-year position to cover my teaching (70% research and 30% teaching).

01.07.2025 04:46 β€” πŸ‘ 57    πŸ” 49    πŸ’¬ 4    πŸ“Œ 1
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Finally arrived at the beautiful Wellcome Genome Campus after a long train journey from Scotland! Looking forward to #EBECancer25

29.06.2025 18:08 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Excited to share our new study on how resistance to AKT inhibition is linked to lineage differences within breast cancer πŸ‘‡πŸ½ Stellar work @colindhratcliffe.bsky.social www.biorxiv.org/content/10.1...
and also surprisingly/worryingly good AI generated podcast 🎧 notebooklm.google.com/notebook/28e...

17.06.2025 08:44 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential.
πŸ”— All positions: ki.se/en/about-ki/...

25.06.2025 10:00 β€” πŸ‘ 81    πŸ” 79    πŸ’¬ 0    πŸ“Œ 3

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

23.06.2025 14:29 β€” πŸ‘ 66    πŸ” 87    πŸ’¬ 0    πŸ“Œ 7
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Organoids in a dish are next to one another. Treatment stops some of them from growing but their neighbours just keep going. What’s the difference? Hint: it’s not genetic

doi.org/10.1101/2025...

18.06.2025 07:33 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Announcement image - dark blue background with coloured overlapping circles
 
Top shows the Cancer Research UK Manchester Institute Logo
 
Centre shows a photograph of Professor Samra Turajlić
 
Text says:
 
"A warm welcome to our new Director, Professor Samra Turajlić, from all staff and students at the Cancer Research UK Manchester Institute"

Announcement image - dark blue background with coloured overlapping circles Top shows the Cancer Research UK Manchester Institute Logo Centre shows a photograph of Professor Samra Turajlić Text says: "A warm welcome to our new Director, Professor Samra Turajlić, from all staff and students at the Cancer Research UK Manchester Institute"

We are delighted to announce, along with Cancer Research UK (@cancerresearchuk.org), The University of Manchester (@manchester.ac.uk) and The Christie NHS Foundation Trust, the appointment of Professor Samra TurajliΔ‡ as our new Director! ⭐

Full story here: www.cruk.manchester.ac.uk/news/profess...

18.06.2025 09:21 β€” πŸ‘ 52    πŸ” 10    πŸ’¬ 0    πŸ“Œ 8
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Organoids Are Us 2025 Further information about this event including our invited speakers and conference programme are available in the tabs below. If you have any questions, please contactΒ organoids-are-us@crukscotlandinstitute.ac.uk

Join us for Organoids Are Us 2025, a symposium featuring #organoids, #stemcells, #cancer, inflammatory disorders and infectious disease.

πŸ“†23-26 Sep 2025

πŸ“Glasgow, UK

Early bird registration ends 15 June. Register below! πŸ‘‡

www.crukscotlandinstitute.ac.uk/events/organ...

11.06.2025 08:45 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Organoids Are Us 2025 is coming to Scotland. Register now! - the Node The MRC National Mouse Genetics Network, in collaboration with the Cancer Research UK (CRUK) Scotland Institute, is organising Organoids Are Us 2025, a

Organoids Are Us 2025

πŸ“… 23 - 26 September
πŸ“Glasgow, Scotland

Early bird registration deadline: 15 June

Organised by @mrcmousenetwork.bsky.social‬ and @cruk-si.bsky.social‬

Find out more:

07.06.2025 08:05 β€” πŸ‘ 6    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
Abstracts and posters | Cancer Neuroscience | The European Association for Cancer Research

We’re so excited for the
Cancer Neuroscience EACR conference!
πŸ“Bilbao, Spain
πŸ“… 14-16 Oct 2025

‼️Upcoming abstract and travelgrant deadline *June 30th* ‼️

Looking forward to seeing many of you there! πŸ§ πŸ”¬

#cancerneuroscience @helloeacr.bsky.social #neuroscience #cancer

Submit your abstract here πŸ‘‡

08.06.2025 15:48 β€” πŸ‘ 20    πŸ” 10    πŸ’¬ 0    πŸ“Œ 2

@xiaofu90 is following 20 prominent accounts