Takashi Akera Lab

Hey #CellBio2025, want to learn how rRNAs tell the cell about the quantity of ribosmal DNA in the genome? Come by poster board 054 this afternoon to learn about the lab's recent work!

Huge congrats Ben!!🎉

Anthony A. Hyman will become EMBL’s next Director General.

He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999.

www.embl.org/news/people-...

We had a nice cycling trip on a perfect autumn day to celebrate Takaya’s recent paper!🚲 Congrats again!🎉

www.cell.com/current-biol...

Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.

(Please repost to reach a broad audience.)

🌍Open call: Junior Group Leader positions!

Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.

Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...

Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...

The synaptonemal complex component corolla regulates meiotic crossover formation in Drosophila melanogaster - Chromosoma In Drosophila melanogaster females, as in most organisms, the segregation of homologous chromosomes in meiosis depends on the formation of crossovers between them. In most cases, crossovers require th...

Very exciting news: My first first-author paper is now out (open access!) in Chromosoma! link.springer.com/article/10.1...

Don’t look away.

What some people call ‘suicidal empathy’ other (medical professionals) might call ‘psychopathy’

Wow. Neat. Congratulations!!!

Among the anti-recombinases, FIGNL1 rules them all. So much that inactivating it brings BRCA2-deficient cells to life. Who is responsible for RAD51 loading without BRCA2/FIGNL1, check out the paper to find out! Great collaboration with @raychaudhurilab.bsky.social

www.science.org/doi/10.1126/...

Brandeis University honors Fred Hutch molecular biologist Dr. Steven Henikoff, a molecular biologist at Fred Hutch Cancer Center, has won the prestigious Rosenstiel Award for Distinguished Work in Basic Medical Research from Brandeis University recognizing h...

Dr. Steven Henikoff receives the 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research.
www.brandeis.edu/rosenstiel/r...

(Personal note: I continue to be inspired and astonished by my postdoctoral mentor & current colleague)

Meet Paul Maddox Paul Maddox is a world-renowned cancer researcher, two-time entrepreneur, and native son of Western North Carolina–and now, a candidate for U.S. Congress. ....

🧪hey all, a friend and colleague, @maddoxfornc.bsky.social, is running for Congress in North Carolina. He is a scientist, professor, and parent, perspectives that are especially important right now. I hope you will support his run for Congress. Find out more here: www.maddoxforcongress.com/about/

PAUL MADDOX ANNOUNCES FOR NORTH CAROLINA’S 11TH CONGRESSIONAL DISTRICT | Paul Maddox for Congress

"There’s a cancer running through Washington, D.C., and I’m running to cure it." #NC11

www.maddoxforcongress.com/2025/10/24/l...

A pumpkin carved to depict an agarose gel electrophoesis with all lanes blank apart from the size ladder on the left and a single band in the lane on the far right

When all your PCRs fail, except for the negative control 😱

Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it?

Turns out we can harness the power of bacteria to power the world’s smallest machines.

1/7 ⚛️🧪

Enhancer-promoter compatibility is mediated by the promoter-proximal region Gene promoters induce transcription in response to distal enhancers. How enhancers specifically activate their target promoter while bypassing other promoters remains unclear. Here, we find that the p...

What is a promoter? And how does it work?

We very happy to share our latest work trying to understand enhancer-promoter compatibility.
I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters

www.biorxiv.org/content/10.1...

Happy Sunday ovo-lovers! A new issue of #cebooc is here!

biomed.news/bims-cebooc/...

This week 2 stunning highlights: pubmed.ncbi.nlm.nih.gov/41129643/ and pubmed.ncbi.nlm.nih.gov/41131150/

Thanks @biomednews.bsky.social for preselecting!

Hijacking a bacterial ABC transporter for genetic code expansion - Nature Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel…

非天然アミノ酸の効率的導入

タンパク質設計における非天然アミノ酸の導入のボトルネックに、細胞内取り込み効率の低さがある。今回細菌のトランスポーターを利用/改変して同時に最大2つの非天然アミノ酸を高効率に導入する手法を確立。基礎から応用まで発展に期待
www.nature.com/articles/s41...

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

Scm3 interacts with the N-terminal tail of Cse4 to regulate kinetochore assembly in budding yeast https://www.biorxiv.org/content/10.1101/2025.10.20.683541v1

BREAKING: Friday night massacre underway at CDC. Doznes of "disease detectives," high-level scientists, entire Washington staff and editors of the MMWR (Morbidity and Mortality Weekly Report) have all been RIFed and received the following notice:

Early career group leaders We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.

The @crick.ac.uk is recruiting Early Career Group Leaders

- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology

Deadline 27 Nov

www.crick.ac.uk/careers-stud...

How do SMC complexes load onto DNA to get ready for loop extrusion?

@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️.

Check out the new paper: www.cell.com/molecular-ce...

Full text in links

Full text in links

Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...

Senior Research Technician at University of Birmingham Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

The medicine Nobel Prize goes to 3 scientists for work on peripheral immune tolerance Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were honored for research into how the body helps the immune system avoid attacking your own tissues instead of foreign invaders.

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were honored for research into how the body helps the immune system avoid attacking your own tissues instead of foreign invaders.

PhD or Master's position available for Fall 2026!

Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!

Congrats Mia and Mike🎉 Great paper for journal club!