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Takashi Akera Lab

@takashiakeralab.bsky.social

Tenure-Track PI @nih_nhlbi. Cell biology๐Ÿ”ฌof non-Mendelian segregation ๐Ÿงฌ(meiotic drive) and species barrier in ๐Ÿญ https://www.nhlbi.nih.gov/science/chromosome-dynamics-and-evolution

820 Followers  |  594 Following  |  35 Posts  |  Joined: 12.11.2024  |  1.9294

Latest posts by takashiakeralab.bsky.social on Bluesky

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ASCB Announces Miriam Segura as New Editor-In-Chief for Its Education Journal CBE-Life Sciences Education (LSE) - ASCB The American Society for Cell Biology (ASCB) is pleased to announce the appointment of Miriam Segura, PhD, as the next Editor-In-Chief of its education journalโ€”CBEโ€”Life Sciences Education (LSE) โ€”begin...

Miriam Segura has been named the next Editor-in-Chief of CBEโ€“Life Sciences Education, ASCBโ€™s education journal. She begins her term August 1, 2025, bringing a bold vision to expand access and impact.

www.ascb.org/society-news...

05.08.2025 12:13 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Spindle checkpoint can secure additional cheating time for selfish expanded centromeres Expanded centromere DNA repeats violate Mendelโ€™s law of segregation by preferentially segregating to the egg in animals and plants. Using oocytes collected from hybrid mice, Walton et al. show that th...

Spindle checkpoint can secure additional cheating time for selfish expanded centromeres cell.com/current-biol...
@currentbiology.bsky.social @takashiakeralab.bsky.social

04.08.2025 17:12 โ€” ๐Ÿ‘ 23    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Transient APC/C inactivation by mTOR boosts glycolysis during cell cycle entry - Nature APC/C activity is transiently inhibited to generate a pulse of glycolysis that is required for mammalian cell cycle entry.

new out in Nature: cell cycle meets metabolism
www.nature.com/articles/s41...

31.07.2025 07:51 โ€” ๐Ÿ‘ 15    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿšจ 2 ร— PhD positions @EPFL! ๐Ÿšจ
Help us push the boundaries of fluorescence microscopy - DNA nanotech, custom optics & spatial omics in Lausanne ๐Ÿ‡จ๐Ÿ‡ญ. Start Jan 2026. Send CV + motivation + 2 refs โ†’ fschueder@ethz.ch
#PhD #Hiring #microscopy #SuperResolution #SpatialOmics #DNAPAINT #FLASHPAINT

31.07.2025 08:56 โ€” ๐Ÿ‘ 20    ๐Ÿ” 19    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Respiratory viral infections awaken metastatic breast cancer cells in lungs - Nature Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by epidemiological d...

Delighted to see this story out and collaborate with amazing teams led by @jdegregori.bsky.social Mercedes Rincon & @roelvermeulen.bsky.social. Proud to see science propelled by our lab @cdi-einstein.bsky.social expanded to better understand cancer dormancy. Congrats! www.nature.com/articles/s41...

30.07.2025 16:15 โ€” ๐Ÿ‘ 35    ๐Ÿ” 11    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2
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Head of the Cell Biology and Biophysics Unit The European Molecular Biology Laboratory (EMBL) is Europeโ€™s flagship life sciences organisation, and one of the worldโ€™s leading research institutions. An intergovernmental organisation of 29 Member S...

EMBL Cell Biology and Biophysics department is searching for a new director. A major position to lead this field in Europe and beyond.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

29.07.2025 07:50 โ€” ๐Ÿ‘ 53    ๐Ÿ” 64    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 4

Time to register is running out! One day left!

30.07.2025 17:05 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Group Leader โ€“ Molecular Systems Biology Unit Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...

Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!

30.07.2025 15:14 โ€” ๐Ÿ‘ 71    ๐Ÿ” 78    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Group Leader - Genome Biology Unit Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

To all post-docs: The Genome Biology dept โ€ช@embl.org
has an Independent faculty position. Fantastic place to set up your lab โ€“great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

30.07.2025 13:41 โ€” ๐Ÿ‘ 165    ๐Ÿ” 197    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 7
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Two dying breast cancer cells videoed through a microscope. #CellBiology

30.07.2025 02:01 โ€” ๐Ÿ‘ 38    ๐Ÿ” 8    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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We are excited to announce the SMBE Fellows Program! โœ๏ธ

Designed to provide networking and mentorship opportunities to early-career researchers through scientific writing in evolutionary biology for @molbioevol.bsky.social and @genomebiolevol.bsky.social

๐Ÿ“† Aug. 31

๐Ÿ”— smbe.org/smbe-fellows-program

28.07.2025 08:53 โ€” ๐Ÿ‘ 40    ๐Ÿ” 36    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
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If you've ever wanted to know what the actin filaments on the scales in a developing moth wing look like in 3D, here you go!

Kyle DeMarr from @mullinslab.bsky.social acquired these beautiful data on the single objective light sheet at the UCSF Center for Advanced Light Microscopy.

#snouty

26.07.2025 19:18 โ€” ๐Ÿ‘ 52    ๐Ÿ” 13    ๐Ÿ’ฌ 6    ๐Ÿ“Œ 3
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How do enhancer-gene contacts relate to transcription activation? In mouse embryonic stem cells, a combo of STED, oligoFISH & RNA FISH shows that 3% of Dppa3 alleles transcribe. For these, enhancers and promoters come closer (panel E). Stumberger ... Leonhardt & Harz www.biorxiv.org/content/10.1...

26.07.2025 21:36 โ€” ๐Ÿ‘ 64    ๐Ÿ” 30    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

๐Ÿ“ฃHuge congrats to our postdoc, Takaya Totsuka, on his new paper @currentbiology.bsky.social ๐ŸŽ‰ He found that Ca2+ oscillations regulate oocyte spindle rotation! ๐ŸญThe project started during his PhD with Prof. Miho Ohsugi.

Free link: authors.elsevier.com/c/1lUqk3QW8S...

27.07.2025 06:27 โ€” ๐Ÿ‘ 13    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Cell enlargement causes mitotic errors and aneuploidy in cells that evade senescence after CDK4/6 inhibition CDK4/6 inhibitors (CDK4/6i) arrest the cell cycle in G1 leading to cellular overgrowth and p53-dependent senescence. They are used to treat metastatic HR+/HER2-breast cancer, but resistance is common,...

Check out our latest work on cell cycle inhibitors, which has implications for how cancer cells could become resistant to these drugs
#senescence #cellcycle #cancer ๐Ÿงช

www.biorxiv.org/content/10.1...

25.07.2025 16:37 โ€” ๐Ÿ‘ 10    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐ŸŒ๐Ÿ’ซ Snail embryos never looked so fabulous!
Tubulin (white), phospho-histone H3 (pink), and F-Actin (cyan) light up this early stage like a cytoskeletal disco ball.
Image from Clemens Cabernard & Adam von Barnau Sythoff ๐Ÿชฉ๐Ÿงฌ #FluorescenceFriday

25.07.2025 23:11 โ€” ๐Ÿ‘ 94    ๐Ÿ” 30    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3
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Our lab is looking to recruit a new postdoc to join our team. You can visit us at leritlab.org to learn more and submit applications here: faculty-emory.icims.com/jobs/149999/... (or scan the QR in the ad below!) Review will commence in early August.

24.07.2025 18:39 โ€” ๐Ÿ‘ 5    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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๐Ÿ“ข Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Mechanistic Cell and Developmental Biology. More details โžก๏ธ tinyurl.com/3fbkp89c

23.07.2025 13:14 โ€” ๐Ÿ‘ 35    ๐Ÿ” 41    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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Very pleased to say we have an Assistant Professor job opening (tenure track) in the Department of Genetics at Trinity College Dublin! ๐Ÿ˜€
www.jobs.ac.uk/job/DOA399/a... - deadline is August 19th! Please repost!

23.07.2025 13:42 โ€” ๐Ÿ‘ 94    ๐Ÿ” 124    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 4
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1 month to abstract deadline for the first cell biology of the nucleus meeting at @embl.org in many years - organised by the stellar @luskinglab.bsky.social @sarawickstrom.bsky.social Tom Quail & Simone Koehler

Tons of open slots, invited and selected speakers all get 20 mins โค๏ธ

#EESNucleus

23.07.2025 10:49 โ€” ๐Ÿ‘ 58    ๐Ÿ” 34    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

Congrats Iain and the team!!๐ŸŽ‰

24.07.2025 07:28 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Weโ€™re hiring! Our lab at WashU has an opening for a Senior/Staff Scientist position. If you're passionate about ovarian physiology, oocyte quality, and excited to contribute to a dynamic and growing team, weโ€™d love to hear from you! Reach out to me directly for more information.

21.07.2025 22:39 โ€” ๐Ÿ‘ 3    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thanks a lot for highlighting our latest work!!๐ŸŽ‰

20.07.2025 08:55 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thanks a lot, Harmit!!

19.07.2025 10:19 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Spindle checkpoint can secure additional cheating time for selfish expanded centromeres Expanded centromere DNA repeats violate Mendelโ€™s law of segregation by preferentially segregating to the egg in animals and plants. Using oocytes collected from hybrid mice, Walton et al. show that th...

Nice work from @takashiakeralab.bsky.social: Spindle checkpoint can secure additional cheating time for selfish expanded centromeres: Current Biology www.cell.com/current-biol...

18.07.2025 17:33 โ€” ๐Ÿ‘ 48    ๐Ÿ” 15    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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We are looking for new colleagues to come join us in Galway as group leaders (Junior and Senior). The Centre for Chromosome Biology is a great place and it is a good time to join. Please reach out if you want to chat about the opportunity!
www.nature.com/naturecareer...

16.07.2025 08:56 โ€” ๐Ÿ‘ 64    ๐Ÿ” 54    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Pls. share widely

Calling all transposon fans & lovers of genetic innovation

MOBILE GENOME welcomes you in Heidelberg, Nov. 4โ€“7 2025

โ†’ Vibrant & friendly community
โ†’ Cutting-edge talks from mechanisms to physiology
โ†’ Plenty of surprises (TEs never stop innovating)

submit abstract by July 29

16.07.2025 08:43 โ€” ๐Ÿ‘ 61    ๐Ÿ” 47    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

Huge congrats @golobor.bsky.social and @gerlichlab.bsky.social ๐ŸŽ‰

15.07.2025 08:33 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Our new preprint ๐Ÿงฌ๐Ÿ”— www.biorxiv.org/content/10.1...
BRD4-NUT forms liquid-like condensates that locally constrain nucleosomes via BRD4-mediated crosslinkingโ€” physical control of #chromatin by #LLPS transcription condensates. @semeigazin.bsky.social @katsuminami.bsky.social @masaashimazoe.bsky.social

10.07.2025 04:21 โ€” ๐Ÿ‘ 43    ๐Ÿ” 21    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

๐ŸšจOur latest work on selfish centromeres is published @currentbiology.bsky.social ๐Ÿญ๐ŸงฌWe found that the spindle checkpoint contributes to non-Mendelian segregation! Huge congrats to our lab manager, Zaak Walton, who led the project๐ŸŽ‰

Free link:
authors.elsevier.com/a/1lQzN3QW8S...

15.07.2025 00:39 โ€” ๐Ÿ‘ 36    ๐Ÿ” 24    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

@takashiakeralab is following 20 prominent accounts