Takashi Akera Lab

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Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...

Senior Research Technician at University of Birmingham Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

The medicine Nobel Prize goes to 3 scientists for work on peripheral immune tolerance Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were honored for research into how the body helps the immune system avoid attacking your own tissues instead of foreign invaders.

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were honored for research into how the body helps the immune system avoid attacking your own tissues instead of foreign invaders.

PhD or Master's position available for Fall 2026!

Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!

Congrats Mia and Mike🎉 Great paper for journal club!

Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404

The remarkable number of people, me included, who were inspired by her work, life and example is the biggest tribute. Find a way to honor her memory. The wolrd is a bit smaller and sadder with her gone

Meiotic cohesin RAD21L shapes 3D genome structure and transcription in the male germline Deletion of the meiotic subunit RAD21L alters 3D chromatin structure and transcription in the mammalian male germ line.

🚨 New from our lab in #ScienceAdvances!

RAD21L cohesin acts as both a 3D genome architect and a transcriptional gatekeeper in the male germline. Its loss disrupts both structure and function—highlighting the tight link between genome folding and gene regulation

www.science.org/doi/10.1126/...

Congrats on the great work!!🥳

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

Despite These Times...my department is hiring! I really like my department, we have a good mix of disciplines and organisms and we're really low-drama. We also get pizza at faculty meeting. So if you're a computational and structural biologist, join us! 🧪 jobs.rutgers.edu/postings/260...

"If we lose hope, we're doomed."

We must continue Dr. Jane Goodall's mission and all fight for the future of the planet.

Jane Goodall, legendary primatologist, has died at age 91 Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.

JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.

Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91

Dr. Jane Goodall, 1934-2025

An exceptional scientist, and a singular woman in science

#WomeninScience 🐒

www.nytimes.com/2025/10/01/o...

Huge congrats, Chloe!!🎉

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Schematic of MAPK signalling in fission yeast, budding yeast and Metazoa. No MAPK scaffold was known for ERK-like MAPK in fission yeast, as opposed to budding yeast Ste5 and metazoan KSR1/2.

Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction!

Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1

doi.org/10.1101/2025...

Super excited that this story by @borissieber.bsky.social is now on BioRxiv!

For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !

See the thread 👇 and enjoy the paper!

doi.org/10.1101/2025...

Congrats Jen, Adam, and the team!!🎉🥂Love this work.

YouTube video by Stowers Institute for Medical Research How Stowers Scientists Found the DNA Site Where Robertsonian Chromosomes Fuse

🚂 The T2T train keeps rolling: "The formation and propagation of human Robertsonian chromosomes" with Gerton and Garrison labs is out! What's a Robertsonian chromosome? Let Jen tell you herself in this great video, or read our paper: [1/3]
📺 youtu.be/JmlY5omxQVc
📄 www.nature.com/articles/s41...

Know rising stars in biological, medicinal, or pharmaceutical chemistry? Nominate them for a feature. Link to a blog post and the nomination form below!

axial.acs.org/biology-and-...

Drosophila Genetic Database The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

Tenure-track Assistant Professor in Computational Ecology and/or Evolution @columbiauniversity.bsky.social.
Deadline to apply September 30.
Reach out if you have questions.

apply.interfolio.com/172496

Linking Germline Telomere Removal to Global Programmed DNA Elimination in Tetrahymena Genome Differentiation https://www.biorxiv.org/content/10.1101/2025.09.21.677574v1

🎉 Congratulations to Needhi Bhalla, UC Santa Cruz (www.bhallalab.com
), named a 2025 #ASCB Fellow! This honor celebrates her outstanding contributions to cell biology, leadership, & service. Fellows will be recognized at #CellBio2025 in Philadelphia this December. #CellBiology

Enhancing local meiotic crossovers in Arabidopsis and maize through juxtaposition of heterozygous and homozygous regions Nature Plants - This study discovered that locally confined DNA differences boost crossover rates in both Arabidopsis and maize, revealing a conserved mechanism that can accelerate plant breeding...

Excellent work from @piotraz.bsky.social group demonstrating juxtaposition of heterozygous & homozygous regions in maize attracts meiotic recombination to het regions rdcu.be/eHmn9 @natplants.nature.com builds from work we did together in Cambridge on Arabidopsis way back in 2015. Great stuff Piotr!

Congrats @needhibhalla.bsky.social !!🎉🥂

Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah, Department of Nutrition & Integrative Physiology | 12844064 The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...

We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social

”Please inhibit responsibly: Natural and synthetic actin toxins as useful tools in cell biology”

I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!

www.molbiolcell.org/doi/10.1091/...

www.molbiolcell.org/cms/10.1091/...