Konstandia

Multiple sclerosis requires Epstein-Barr virus infection as an underpinning, exhibits self-directed antibodies to EBNA1, the virus's nuclear antigen, representing molecular mimicry. This combines with/ genetic risk factors (Figure, compared w/healthy controls)
@pnas.org
www.pnas.org/doi/epub/10....

NIH to ax grants on vaccine hesitancy, mRNA vaccines Move reflects vaccine skepticism of health secretary Robert F. Kennedy Jr.

NIH to ax grants on vaccine hesitancy, mRNA vaccines. www.science.org/content/arti...

Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence - Nature Cancer Keyl et al. present an explainable artificial intelligence model-based real-world data analysis from over 15,000 patients across 38 cancer types, identified key prognostic marker interactions, and con...

How explainable, multimodal #AI of real world cancer patient data has the potential to increase accuracy of prognosis and optimize treatment
www.nature.com/articles/s43...
@NatureCancer open-access

In an unprecedented move, research-grant reviews have been suspended indefinitely at the world’s largest public funder of biomedical research.

Graphic stories of the impact of Long COVID on people's lives, produced from words of many people and illustrated by Monique Jackson as part of the REACT study.

www.imperial.ac.uk/medicine/res...

this matters - please contribute any US paeds people out there!

📌

Bookmark hack here - thanks! bsky.app/profile/dart...

This is a good workaround for bookmarks

Thread for those new to BlueSky. First of all, welcome. It feels like a safer space, doesn’t it? But also perhaps a bit disorienting initially? Here’s some tips for getting your bearings.

Hi everyone - there's already been an Indie SAGE starter pack, but here's an Indie SAGE list which can pin to your BlueSky home page and then you have a really quick way of catching up on what Indie SAGE members have been posting about!

bsky.app/profile/did:...

'Do I want to work with this person?'

Try this test.

Welcome!

Dean Richard Corsi is wearing an N95 mask and is holding up a UC Davis College of Engineering banner next to two do-it-yourself air cleaners.

My 1st post on Blue Sky!

Happy to be on this new platform and hoping that those who follow me on the other platform rejoin here.

I'll continue to post about indoor air quality, College of Engineering at #UCDavis, and occasionally about dogs & music.

1st image = two #CRBox es & a dean.

Plot of covid outcomes by age for A&E attendance, hospital admission, severe hospital admission and death. Apart from death, rates were highest for babies under 6 months.

THREAD: we urgently need to talk about babies & Covid - AGAIN.

A new paper has dropped looking at acute Covid-19 outcomes from Sep 2023-Apr 2024 by age for all England.

Except for deaths, babies under 6 mths old have HIGHEST risk of A&E, admission & SEVERE hospital admission across ALL ages 1/10

Economic burden of Long Covid in the UK estimated to be >$20 billion per year from real cohort data
bmjopen.bmj.com/content/14/1...

I do think that Twitter, as used by science during the pandemic as a real-time info service for common good, now joins ranks of ‘lost stuff from the olden days’ - like record shops, buying a quarter of wine gums at Woolworth. How to get publishers posting journal content and preprints on #Bluesky?

Latest Covid situation in England 13 Jan 2024 (temporary?) dip in cases, but prevalence remains high

My latest post on what is happening with Covid in England right now:

christinapagel.substack.com/p/latest-cov...

Hope this will lead to funding, education, research, therapeutics and investment for #LongCovid in 2024.

New JN.1 Covid wave ‘may be biggest yet’ as expert warns over 'devious' strain Professor Peter Openshaw, a virus expert at Imperial College London, is warning of a 'major surge' as the JN.1 variant spreads and described the virus strain as 'devious'

'We're going to see quite a major surge in infections over the coming weeks - the wave could be bigger than anything we've seen before - those who haven't received a booster this winter should consider wearing masks in public again'. Prof. @p_openshaw
www.mirror.co.uk/news/uk-news...

Over the coming days, you'll probably hear the media saying COVID levels are peaking. Please remember, that doesn't mean the virus instantly vanishes. It takes time to come down from this very high peak, so virus levels will still be a high for a while. Keep taking precautions.

ID: A purple and blue graphic reads, “THE SICK TIMES: Q&A: Eric Topol on Long Coivd clinical trials and what he’s looking forward to in 2024. By Betsy Ladyzhets. The graphic features a photo of Eric Topol in an aqua, collard shirt with a beige background.”

To start the new year, @betsyladyzhets spoke with @EricTopol for an in-depth interview about the state of Long Covid clinical trials, the Biden Administration's lack of response to the crisis, and more!

Read the full interview here: t.co/ipgVabv1bH

Engineered secretory IgA antibodies vs Omicron (BA.1, BA.2, BA.5) were 25 to 75-fold more potent than shots (->IgG) for neutralization. A single nasal spray dose prevented infections in the mouse model
www.pnas.org/doi/10.1073/...

Opinion | State medical boards should punish doctors who spread false information about covid and va... Thus far, regulatory bodies have failed in this duty.

We announced our 501c3 and website in a Washington Post Opinion article on September 21, 2021.

Our website was a simple tool.
It centralized information needed to file a complaint with any State Medical Board.

It was an honest attempt to stop U.S. licensed doctors spreading disinformation.

To kick off 2024 @thesicktimes.bsky.social, I'm very excited to share an interview with @erictopol.bsky.social: discussing #LongCovid clinical trials, NIH RECOVER, and what he's looking forward to in 2024.

Winter bugs and what we should do about it. Winter looks like it could be bad one

Really good from @sheencr.bsky.social On the current COVID immunity and vaccine situation in the UK.
open.substack.com/pub/sheenacr...

Vaccines reduce the risk of long COVID in children A study shows that US children who received mRNA COVID-19 vaccines have some protection against developing long-lasting symptoms of the coronavirus SARS-CoV-2. A study shows that US children who recei...

A new study shows that vaccinated children are less likely than unvaccinated children to develop Long COVID. Please get your family boosted with the updated COVID vaccine!

Best: Munich
Worst: Heraklion ….

Covid in England update: expect a bumpy Christmas and New Year Unfortunately not good news this week for England. The rise of the JN.1 subvariant of the “Pirola” variant that emerged globally in August is causing significant waves all over the world, particul...

My latest substack on what looks like it will be a bad month for the NHS and those needing its services.
Flu is back, Covid is going up (driven by a new subvariant) and waning immunity means that for many it's still a pretty unpleasant experience.

tinyurl.com/3svmcu9x

Opinion | Reporting on Long Covid Taught Me to Be a Better Journalist Covering long Covid solidified my view that science is not the objective, neutral force that it is often said to be.

“Covering long Covid solidified my view that science is not the objective, neutral force it is often misconstrued as. It is instead a human endeavor, relentlessly buffeted by our culture, values and politics.”

Ed Yong on the possibilities of journalism (gift link):
www.nytimes.com/2023/12/11/o...