Torben Heick Jensen's Avatar

Torben Heick Jensen

@heick.bsky.social

RNA decay, RNA sorting, gene expression

767 Followers  |  1,795 Following  |  7 Posts  |  Joined: 14.11.2024  |  1.501

Latest posts by heick.bsky.social on Bluesky


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Molecular basis of polyadenylated RNA fate determination in the nucleus Eukaryotic genomes generate a plethora of polyadenylated (pA+) RNAs[1][1],[2][2], that are packaged into ribonucleoprotein particles (RNPs). To ensure faithful gene expression, functional pA+ RNPs, in...

How are RNAs sorted for export vs. degradation in the nucleus? In collaboration with @heick.bsky.social’s lab we (@clemensplaschka.bsky.social and @juliusbrennecke.bsky.social labs) discovered a direct mechanistic link between the export and decay machineries: www.biorxiv.org/content/10.1... (1/x)

22.09.2025 23:23 β€” πŸ‘ 90    πŸ” 43    πŸ’¬ 2    πŸ“Œ 2
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A molecular switch orchestrates the nuclear export of human messenger RNA The nuclear export of messenger RNA (mRNA) is a key step in eukaryotic gene expression ([KΓΆhler and Hurt, 2007][1]). Despite recent insights into the packaging of newly transcribed mRNAs into ribonucl...

Dream collaboration with the groups of Torben Heick Jensen (@heick.bsky.social; @au.dk) and Clemens Plaschka (@impvienna.bsky.social). Building in part on the incredible work from Ulrich Hohmann on human mRNA export.
www.biorxiv.org/content/10.1...

17.09.2025 12:42 β€” πŸ‘ 30    πŸ” 7    πŸ’¬ 2    πŸ“Œ 1
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A postdoc position in the Torben Heick Jensen lab, Aarhus University, Denmark: Mammalian Nuclear RNA Production and Turnover Systems - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University

Final call for postdoc positions in Aarhus, Denmark. Sorting of gene expression and beyond. Please get in touch for further information or apply using this link:
mbg.au.dk/en/news-and-...

05.08.2025 08:06 β€” πŸ‘ 13    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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A postdoc position in the Torben Heick Jensen lab, Aarhus University, Denmark: Mammalian Nuclear RNA Production and Turnover Systems - Ledig stilling pΓ₯ Aarhus Universitet Ledig stilling ved Institut for MolekylΓ¦rbiologi og Genetik - RNA-biologi og -innovation, Aarhus Universitet

Second call for postdoc positions in the lab. Please follow the link below to apply or get in touch for further information.
mbg.au.dk/aktuelt/ledi...

18.07.2025 09:28 β€” πŸ‘ 3    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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A postdoc position in the Torben Heick Jensen lab, Aarhus University, Denmark: Mammalian Nuclear RNA Production and Turnover Systems - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University

Postdoc positions available in the Heick Jensen lab in sunny Aarhus. Sorting of good and bad RNAs in mammalian nuclei. Please get in touch for further information and/or use the following link to apply:
mbg.au.dk/en/news-and-...

27.06.2025 06:03 β€” πŸ‘ 13    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1

Thrilled to see my work with @adelmanlab.bsky.social on INT/dsRNA highlighted by @willgarland.bsky.social and @heick.bsky.social ! Thanks for beautifully capturing how nuclear RNA guardians prevent cellular chaos. The ripple effects of transcriptional dysregulation are indeed profound! #RNABiology

19.06.2025 19:47 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - BiRC - Bioinformatics Research Center, Aarhus University

πŸ“£ πŸ₯³ πŸ§‘β€πŸ’» Our department is hiring:

Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark

Deadline June 1st

Thanks for sharing!

mbg.au.dk/en/news-and-...

16.05.2025 12:35 β€” πŸ‘ 70    πŸ” 90    πŸ’¬ 0    πŸ“Œ 0
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Postdoc positions in Nuclear RNA Biology - Ledig stilling pΓ₯ Aarhus Universitet Ledig stilling ved Institut for MolekylΓ¦rbiologi og Genetik - RNA-biologi og -innovation, Aarhus Universitet

Second call for a postdoc position in my lab. Please read more and apply here: mbg.au.dk/aktuelt/ledi...

04.03.2025 15:23 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

PhD position vacant in the lab. Please spread the news. Study topic: Mammalian nuclear RNA production and turnover systems. Learn more about the lab here: www.mRNP.au.dk

20.02.2025 09:53 β€” πŸ‘ 8    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
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Postdoc positions in Nuclear RNA Biology - Ledig stilling pΓ₯ Aarhus Universitet Ledig stilling ved Institut for MolekylΓ¦rbiologi og Genetik - RNA-biologi og -innovation, Aarhus Universitet

Postdoc positions on nuclear RNA biology available in the Heick Jensen lab. Come join us in tiny Denmark. Interested? - then follow this link: mbg.au.dk/aktuelt/ledi...

12.02.2025 09:02 β€” πŸ‘ 23    πŸ” 26    πŸ’¬ 1    πŸ“Œ 0
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First paper of our lab today @natureportfolio.bsky.social by Nussi!

We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!

@embl.org #RNAbiology #RNASky

t.co/a24Xxcxdo0

04.12.2024 20:53 β€” πŸ‘ 257    πŸ” 78    πŸ’¬ 15    πŸ“Œ 8
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Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes The CCR4-NOT complex is a major regulator of eukaryotic messenger RNA (mRNA) stability. Slow decoding during translation promotes association of CCR4-NOT with ribosomes, accelerating mRNA degradation....

I’m thrilled to share a collaborative story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu. We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation!
www.science.org/doi/10.1126/...

22.11.2024 18:09 β€” πŸ‘ 129    πŸ” 45    πŸ’¬ 3    πŸ“Œ 8

A Starter Pack to connect with political scientists at Aarhus University πŸ₯³

go.bsky.app/CbDyBb1

21.11.2024 20:17 β€” πŸ‘ 34    πŸ” 11    πŸ’¬ 0    πŸ“Œ 1
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Exciting highlights of the recent complex life of #RNA symposium @embl.org featuring Matt Disney, Juan Valcarcel, @lapassmore.bsky.social, Herve Le Hir, Andreas Meyer, Yiliang Ding, Seitz Herve, Maria Hondele, @juliusbrennecke.bsky.social, Bahareh Torkzaban

www.embl.org/news/science...

21.11.2024 14:12 β€” πŸ‘ 43    πŸ” 10    πŸ’¬ 1    πŸ“Œ 0

go.bsky.app/77FHCU1

13.11.2024 18:16 β€” πŸ‘ 11    πŸ” 8    πŸ’¬ 1    πŸ“Œ 0

And RNA for that matter

17.11.2024 10:32 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Are there any "Bluesky transcription starter packs"?

17.11.2024 09:56 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1

@heick is following 20 prominent accounts