@glgalea.bsky.social
Neuroembryologist. Mechanobiologist. Vet.
Figure excerpt showing recoil following annual laser ablation of WT and VANGL2-knock in neuroepithelial cultures
2. iPSC neuroepithelial models by @hpscenthusiast.bsky.social identifying a patient mutation in VANGL2 which diminishes apical constriction in this human model
www.biorxiv.org/content/10.1...
Illustration of the mouse cranial neural folds and quantification of recoil following laser ablations in the midline or lateral neural folds
1. Laser ablation study of the mouse cranial neuroepithelium, led by Juana de la O in Adam Martin's lab (MIT), identifying regional differences in apical tension and anisotropy in the lateral neural folds (consistent with a recent paper from Eric Brooks' lab)
www.biorxiv.org/content/10.1...
#ApicalConstriction and #DevBio afficionados - we've got two new pre-prints you may be interested in, below:
20.05.2025 14:30 — 👍 6 🔁 2 💬 1 📌 0A lateral tension model for cranial mouse neural tube closure https://www.biorxiv.org/content/10.1101/2025.05.15.654327v1
16.05.2025 07:30 — 👍 0 🔁 1 💬 0 📌 0A couple of weeks left to apply to join Development's *Pathway to Independence* programme
Support & mentoring for post-docs on the academic job market
Deadline: January 31
journals.biologists.com/dev/pages/pi...
Applications are now open for our UCL East London Scholarship. The value of the bursary is full home tuition fees plus £16,000 maintenance. The deadline is Thursday 26 June 2025. Find out more, including eligibility criteria: www.ucl.ac.uk/scholarships...
18.12.2024 16:29 — 👍 4 🔁 5 💬 0 📌 0We're hiring a postdoc! Please forward to people you know who are looking for positions.
Interested in studying how metabolism is wired to support fertility? 🔬🪰 Come join us!
Ad to go live next week, but informal enquiries encouraged.
Applications open for a new cohort of @dev-journal.bsky.social *Pathway to Independence* fellows
Know a #devbio post-doc about to enter the academic job market?
Would they benefit from a little support & mentoring?
Spread the word
Deadline 31 Jan 2025
journals.biologists.com/dev/pages/pi...
To mark Black Friday, we are excited to share our latest work, "Planar polarized force propagation integrates cell behavior with tissue shaping during convergent extension." Now online in Current Biology. authors.elsevier.com/a/1kATd3QW8S...
30.11.2024 03:32 — 👍 30 🔁 9 💬 2 📌 2Congrats to Fernanda - she really came up with some really creative solutions to our questions!
22.11.2024 07:03 — 👍 1 🔁 0 💬 0 📌 0Happy to share our new preprint with Vernanda Perez-Verdugo, @shilabanerjee.bsky.social @glgalea.bsky.social We show that mechanical feedback drives shape and spatial order of the surface ectoderm in hindbrain neuropore closure.
22.11.2024 06:45 — 👍 4 🔁 1 💬 0 📌 0How do physical forces influence spatiotemporal cell patterning during tissue morphogenesis? Our latest preprint integrates theoretical modeling with live imaging of mouse embryos to reveal how mechanosensitive feedback drives self-organized cell patterning during hindbrain neuropore morphogenesis.
22.11.2024 00:39 — 👍 35 🔁 10 💬 2 📌 0
