Julieth Murillo's Avatar

Julieth Murillo

@dynamicnetworks.bsky.social

Computational Biologist. Cambridge, UK

37 Followers  |  130 Following  |  2 Posts  |  Joined: 23.11.2024  |  2.167

Latest posts by dynamicnetworks.bsky.social on Bluesky

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Petition: Review all trade ties with Israel, suspend 2030 roadmap & impose trade sanctions We call on the Government to review existing trade ties with Israel, suspend the 2030 Roadmap for UK-Israel bilateral relations and impose trade sanctions upon Israel.

Please sign this Parliamentary petition calling for comprehensive trade sanctions on Israel - the limited sanctions on specific members of the Israeli Government by the UK do not go far enough: petition.parliament.uk/petitions/72...

05.08.2025 18:09 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Challenges and opportunities for the next generation of computational tumor models Mathematical models have become essential tools for exploring the complex interplay between cancer cells and their microenvironment, but require multidisciplinary expertise and abundant biological dat...

Mathematical models are essential tools for exploring the complex interplay between #cancer cells and their environment, but require expertise and abundant data to develop. Lance Munn & Rakesh Jain suggest that #AI is leading the way towards the next wave of tumor models ๐Ÿงช plos.io/4ofREUk

05.08.2025 16:15 โ€” ๐Ÿ‘ 4    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Research Fellow - Department of Immunology and Immunotherapy - 106119 - Grade 7 The successful candidate will make extensive use of a range of in vivo models of fungal infection and will have access to the wide range of transgenic tools and in vivo immunology techniques establish...

Job ads for TWO postdoctoral positions available in our group are now online. Deadline August 25th.
๐ŸงชImmunologists, apply in link below.
๐Ÿ„Microbiologists- please follow link in next post.
edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

30.07.2025 12:15 โ€” ๐Ÿ‘ 11    ๐Ÿ” 15    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Probabilistic migration events drive transient tissue residency of lymphocytes during homeostasis Tissue-resident lymphocytes form a phenotypically and functionally distinct analog to the corresponding circulatory lymphocyte populations. Residential CD8 T cells, in particular, are identified as having prolonged residence in the tissues and key functions in recall responses at tissue-environmental interfaces, although the dwell time in individual tissues has yet to be resolved. Residential CD4 T cells, regulatory T cells, B cells, and NK cells have been demonstrated to share phenotypic properties with residential CD8 T cells, but the migratory kinetics are even more poorly defined. Here we used probabilistic modelling on a large parabiosis dataset, covering multiple time-points and tissues, to calculate migration kinetics and dwell times of multiple lymphocyte subsets across a diverse set of tissues. Markov chain modelling identified distinct cell type-specific and tissue-specific residency patterns. The liver and gut were prone to prolonged residency compared to other tissue types, and a hierarchy of residency was observed with CD8 T cells and NK cells demonstrating longer residency than CD4 conventional T cells and regulatory T cells, which in turn resided in tissues longer than B cells. With few exceptions, however, average residency was at least an order of magnitude shorter than the life-span of the mouse, indicating a more dynamic form of steady-state tissue residency than usually assumed. Together these data provide a comprehensive model of a pan-tissue shared program in lymphocyte tissue residence, as well as identifying cell type- and organ-specific modification of the migratory kinetics. ### Competing Interest Statement The authors have declared no competing interest. Wellcome Trust, https://ror.org/029chgv08, 222442/Z/21/Z European Research Council, TissueTreg

I'm excited about a new @biorxivpreprint.bsky.social story that just went live! This one takes a #computational #immunology approach to understanding #tissueresident lymphocytes. The story highlights the extra value mathematical modelling can bring to biology. ๐Ÿงต1/10

www.biorxiv.org/content/10.1...

09.07.2025 08:17 โ€” ๐Ÿ‘ 67    ๐Ÿ” 22    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3
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Family hubs to open in every council in England Government says ยฃ500m plan aims to support an extra half a million more children.

Amidst the blizzard of news, this is hardly being reported but will make the biggest difference in peoples' lives www.bbc.co.uk/news/article...

06.07.2025 06:19 โ€” ๐Ÿ‘ 5    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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NHS England ยป NHS waiting list hits two-year low as staff work to โ€˜turn the tideโ€™ The NHS waiting list has fallen to its lowest level in two years, the first April drop since 2008*, as health chiefs hailed staff for continuing to tackle demand and drive progress for patients. New d...

โ€œThe NHS waiting list has fallen to its lowest level in two years, the first April drop since 2008โ€

www.england.nhs.uk/2025/06/nhs-...

06.07.2025 11:33 โ€” ๐Ÿ‘ 10    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

From the same team that made vanilla for ice cream using E.coli that digest plastic waste.

24.06.2025 11:42 โ€” ๐Ÿ‘ 18    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ”ฌ Day 1 of the EMBO Practical Course on Computational Modelling of Multicellular Systems kicks off at the Collaboratorium!

Participants were welcomed by @jamesasharpe.bsky.social, setting the stage for a week of exploring how computational tools help us understand tissue and organ dynamics. ๐Ÿ’ป๐Ÿงฌ

14.06.2025 15:27 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Polygenic scores (PGS) offer insights into a personโ€™s inherited risk of disease.

GeneticScores.org is a new platform that enables secure, cloud-based calculation of polygenic scores to make genomic risk prediction more accessible.

www.ebi.ac.uk/about/news/u...

๐Ÿ–ฅ๏ธ๐Ÿงฌ

09.06.2025 11:20 โ€” ๐Ÿ‘ 19    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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I've just heard our group of runners for @scotrefugeecouncil.bsky.social have almost raised a collective ยฃ15K!!!

We are just under ยฃ500 off our target!

My JustGiving page closes on Sunday... can we do it before?!!

All shares/donations count!

Thank you!! โค๏ธโค๏ธโค๏ธ

www.justgiving.com/page/amy-mci...

30.05.2025 11:46 โ€” ๐Ÿ‘ 176    ๐Ÿ” 53    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 2
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Assistant Teaching Professor and Course Director, MPhil in Translational Medical Research (Fixed Term) - Job Opportunities - University of Cambridge Assistant Teaching Professor and Course Director, MPhil in Translational Medical Research (Fixed Term) in the Department of Medicine at the University of Cambridge.

๐ŸšจNew vacancy at @cam.ac.uk๐Ÿšจ

The Department of Medicine at the University of Cambridge is looking for an Assistant Teaching Professor and Course Director for the new MPhil in Translational Medical Research.

๐Ÿ“ฉ Apply by 22 June:

28.05.2025 10:01 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿšจ Abstract Deadline - Friday 30th May

There are 10 days left to submit your abstract for EMDS2025. We have >20 selected talk slots - so submit an abstract today!

All details & programme: www.emds2025.com

@britsocimm.bsky.social @societymucosalimm.bsky.social @cytokinesociety.bsky.social

20.05.2025 05:36 โ€” ๐Ÿ‘ 6    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Latin-American genetic data available securely to approved researchers worldwide/Datos genรฉticos latinoamericanos disponibles para investigadores de todo el mundo

Big news for health data research and population diversity: The Mexico City Prospective Study data are now available securely to approved researchers worldwide. www.ndph.ox.ac.uk/news/latin-a...

Cohort description: www.ctsu.ox.ac.uk/research/pro...

02.05.2025 09:05 โ€” ๐Ÿ‘ 33    ๐Ÿ” 17    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2
A promotional flyer for the AI@MBL: Machine Learning for Microscopy Image Analysis course at the Marine Biological Laboratory. Course dates are Aug 22 to Sept 6, 2025, with applications due April 30. The image includes a brief paragraph: "This two-week course will familiarize researchers with state-of-the-art deep learning techniques for microscopy image analysis." The image also includes the hashtag #ScienceStartsHere, a logo for the MBL, and an abstract image with different colored blobs.

A promotional flyer for the AI@MBL: Machine Learning for Microscopy Image Analysis course at the Marine Biological Laboratory. Course dates are Aug 22 to Sept 6, 2025, with applications due April 30. The image includes a brief paragraph: "This two-week course will familiarize researchers with state-of-the-art deep learning techniques for microscopy image analysis." The image also includes the hashtag #ScienceStartsHere, a logo for the MBL, and an abstract image with different colored blobs.

โš ๏ธ Course deadline extension โš ๏ธ

The last day to apply for the AI@MBL course this summer is now April 30!
๐Ÿ“ฒ Read more and apply: bit.ly/43vIT0u

#ScienceStartsHere

16.04.2025 22:26 โ€” ๐Ÿ‘ 8    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Tissue-specific improvements in CD4+ T cell responses after treatment for visceral leishmaniasis. https://www.biorxiv.org/content/10.1101/2025.04.13.648617v1

14.04.2025 04:15 โ€” ๐Ÿ‘ 1    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Join us for this @dgz.bsky.social seminar online with very cool talks about the Cell biology of the immune system

There will be of course some #CellMigration of leukocytes ;)

Speakers: @liz-kurtz.bsky.social, #ZahraaA, @labliston.bsky.social and #StefanU

11.04.2025 14:49 โ€” ๐Ÿ‘ 8    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A flyer for the MBL Falmouth Forum series. It has the date, time, and location of the event (Friday, April 11, 7:30pm, Cornelia Clapp Auditorium), a photo of speaker Paul Catanzaro with info on him (professor, State Extension Forester, co-director of the Family Forest Research Center, UMass Amherst), a link to the join the talk virtually, a logo for the MBL, and information on how the forum series is supported.

A flyer for the MBL Falmouth Forum series. It has the date, time, and location of the event (Friday, April 11, 7:30pm, Cornelia Clapp Auditorium), a photo of speaker Paul Catanzaro with info on him (professor, State Extension Forester, co-director of the Family Forest Research Center, UMass Amherst), a link to the join the talk virtually, a logo for the MBL, and information on how the forum series is supported.

๐Ÿ“† Don't forget to join us TOMORROW, Friday, April 11, for a special MBL Falmouth Forum with Paul Catanzaro!

His talk will begin at 7:30 p.m. in the MBL's Lillie Laboratory. Can't make it in person? That's okay, we'll be streaming live! mbl.edu/falmouth-forum

10.04.2025 19:11 โ€” ๐Ÿ‘ 9    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

OK here it is, the moment you have all been waiting for! Our advert for 5 posts here at Glasgow: Cognitive neuroscience/psychology. Closing date May 12 - please spread the word
www.nature.com/naturecareer...

28.03.2025 07:06 โ€” ๐Ÿ‘ 121    ๐Ÿ” 140    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3

Do any of my #tbsky friends have interests in T cell responses in people with evidence of prior Mtb infection?

If so, would you have any interest in looking at T cell responses to Mtb-derived peptides that we have detected by mass spectrometry? LMK ๐Ÿ™๐Ÿฝ

28.03.2025 18:04 โ€” ๐Ÿ‘ 7    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ“„ Update on our preprint about Gene Regulatory Net (GRN) benchmarking ๐Ÿ“„
We have included the original and decoupled version of SCENIC+, added a new metric and two more databases. Dictys and SCENIC+ outperformed others, but still performed poorly in causal mechanistic tasks.
doi.org/10.1101/2024... ๐Ÿ‘‡

14.03.2025 10:34 โ€” ๐Ÿ‘ 49    ๐Ÿ” 18    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

๐Ÿ˜ฎ I feel seen.

12.02.2025 10:03 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Graphical abstract of BioChatter

Graphical abstract of BioChatter

Applying LLMs to biomedical research today can go one of two ways: we either use a closed-source web app, or we get coding ourselves. Many researchers lack training for the latter, so their only choice is the former. We want to change that. www.nature.com/articles/s41...

05.02.2025 09:15 โ€” ๐Ÿ‘ 78    ๐Ÿ” 37    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2
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Organoids have incredible potential in drug discovery and disease modelling.

In this Scientific Computing World interview, @iguaracy.bsky.social discusses organoid construction, nanobots, and how bioinformatics is transforming biomedical research.

www.scientific-computing.com/article/usin...

04.02.2025 11:09 โ€” ๐Ÿ‘ 22    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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PhosX: data-driven kinase activity inference from phosphoproteomics experiments AbstractSummary. The inference of kinase activity from phosphoproteomics data can point to causal mechanisms driving signalling processes and potential dru

Kinases play a role in many diseases, making them prime targets for therapeutic intervention.

Enter PhosX, a new tool transforming the way researchers analyse and interpret kinase activity.

Read the full article: academic.oup.com/bioinformati...

@alussana.bsky.social @epetsalaki.bsky.social

27.01.2025 11:56 โ€” ๐Ÿ‘ 21    ๐Ÿ” 14    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

๐Ÿ’•๐Ÿ’•๐Ÿ‡จ๐Ÿ‡ด

21.01.2025 19:17 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Join the Biology of Parasitism (BoP) course at MBL Woods Hole for an unforgetttable summer of science and fun, meet wonderful teachers and make friends for life: www.mbl.edu/education/ad...

09.01.2025 23:24 โ€” ๐Ÿ‘ 11    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Flyer for the MBL's 2025 Embryology course

Flyer for the MBL's 2025 Embryology course

๐Ÿ””Apply now!๐Ÿ””

January 22 is the last day to apply to the MBL's 2025 Embryology course! This comprehensive overview of modern developmental biology is open to graduate students, postdoctoral fellows, and senior researchers.

Learn more: bit.ly/3DKPMjH
#ScienceStartsHere

08.01.2025 13:55 โ€” ๐Ÿ‘ 26    ๐Ÿ” 20    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3
GRETA graphical abstract

GRETA graphical abstract

We present Gene Regulatory nETwork Analsyis (GRETA), a framework to infer, compare and evaluate gene regulatory networks #GRNs. With it, we have benchmarked multimodal and unimodal GRN inference methods. Check the results here ๐Ÿ‘‡
Paper: doi.org/10.1101/2024.12.20.629764
Code: github.com/saezlab/greta

23.12.2024 08:43 โ€” ๐Ÿ‘ 126    ๐Ÿ” 46    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 5
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Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells - Nature Immunology Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate dendritic cells.

#NoTimeToDie! @inflammasomelab, Holley, Monteleone &co show @natimmunol.bsky.social that cells that die by #pyroptosis, or #necroptosis, are crowned with F-actin filopodia that makes them visible by dendritic cells via CLEC9A to initiate adaptive immunity! www.nature.com/articles/s41...

05.12.2024 16:55 โ€” ๐Ÿ‘ 59    ๐Ÿ” 22    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
Text reads: Technical Specialist/ARA. ยฃ32,600 - ยฃ39,200 (ARA)
ยฃ40,500 - ยฃ48,600 (Technical Specialist)
Apply by 10 January
Do you have expertise in human-induced pluripotent stem cells, molecular biology (and in vitro infection models)?

Join a collaborative project in the Haniffa/Lotfollahi labs, to optimise protocols to introduce perturbations and evaluate their effects in a skin organoid model derived from hiPSCs. You will 
have the opportunity to develop your computational skills and learn concepts about machine learning.

Text reads: Technical Specialist/ARA. ยฃ32,600 - ยฃ39,200 (ARA) ยฃ40,500 - ยฃ48,600 (Technical Specialist) Apply by 10 January Do you have expertise in human-induced pluripotent stem cells, molecular biology (and in vitro infection models)? Join a collaborative project in the Haniffa/Lotfollahi labs, to optimise protocols to introduce perturbations and evaluate their effects in a skin organoid model derived from hiPSCs. You will have the opportunity to develop your computational skills and learn concepts about machine learning.

@mhaniffa.bsky.social and Mo Lotfollahi are recruiting!

Do you know your way around hiPSCs, molecular biology, and ideally, in vitro infection models? Are you interested in developing your computational skills?

Apply through the Wellcome Sanger Institute by 10 January

05.12.2024 10:20 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@dynamicnetworks is following 20 prominent accounts