Jim Mansfield

CBS News: Some NYPD officers worry about Mandani becoming NYC mayor the Free Press reports.

Promoting the editor-in-chief's personal side project. Zero named sources in a story that promotes the editor-in-chief's personal political position. Misspelling the subject's name. It took one day for CBS News to become a conservative blog.

www.cbsnews.com/video/some-n...

2025 Nobel winner Philippe Aghion:

'The key factor of economic power is technological leadership'

YouTube video by Prof. Jean Fan RNA velocity in situ infers gene expression dynamics using spatial transcriptomics data

What is RNA velocity in situ? ChatGPT kept getting it wrong...

So I made this video explaining how RNA velocity in situ infers gene expression dynamics by distinguishing nuclear vs. cytoplasmic expression in spatial transcriptomics data: youtu.be/z9Oxf1hvum0

#AcademicSky

The spatial landscape of infectious mononucleosis tonsils @biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...

A master class from MIT in responding to authoritarian overreach:

Your “premise … is inconsistent with our core belief that scientific funding should be based on scientific merit alone.
… America’s leadership in science & innovation depends on independent thinking & open competition for excellence.

Every targeted institution (my own very much included) should cut and paste this letter onto their letterhead.

mitochondria from bipolar patients are closer to the nucleus in these images; control patients' are spread out further

15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵

Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution RAEFISH delivers whole-transcriptome (>20,000 genes) imaging at single-molecule resolution in cells and tissues and enables direct gRNA detection for high-content, image-based CRISPR screens.

🔥Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution

www.cell.com/cell/fulltex...

Or both at the same time!

President Macron: “Europeans, let's wake up!

We have been incredibly naive in entrusting our democratic space to social networks.”

defenddemocracy.eu/macron-democ...

Liberals say that recent Supreme Court ruling have given the executive branch too much power. But they’re wrong, because the rulings only apply to Trump and will all be reversed when there’s a Democratic president.

Johns Hopkins sophomore student Florin Selaru develops a new scheme to deconvolve colors in histological sections for digital pathology.

It greatly outperforms traditional linear color deconvolution.

Congrats Florin!

Read his paper here: www.biorxiv.org/content/10.1...

If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back.

I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support

A lot of people think that every international student admitted means one fewer spot for domestic students, when the opposite is more likely true - the tuition revenue international students bring allows public universities to provide substantial discounts to domestic students, improving access.

Justin hodges, not on bluesky, on PhDs

Has America become so soft and woke that we can't appreciate why all of our top generals need to leave their posts and fly to Virginia to be lectured by the Fox News weekend host about the warrior mentality?

Pleased to update this - The paper is published in Cell Reports!
A long road for this one, the paper grew exponentially and evolved over a couple of years. Thanks to @makris1.bsky.social for sticking with it to untangle all the new data!

@cp-cellreports.bsky.social
www.cell.com/cell-reports...

Quinnipiac in recent poll asked: Do you think that the way people talk about politics these days is contributing to violence in the United States, or don't you think so? 82% of voters agreed with this including majority of Dems, Independents, and GOP. I said basically this and got fired.

"our analysis indicates that substantial NIH budget cuts—including those implemented at the funding margin—could curtail research linked to a large share of potential drug approvals."

The word “autism” was first used to describe behavioral differences in children in 1911 but autism has been documented using available records going back to the 1700s (definitively) and further.

Acetaminophen (Tylenol, paracetamol) was discovered in 1878 and first sold in the United States in 1950.

Federal judge orders Trump to restore $500 million in frozen UCLA medical research grants A San Francisco-based federal judge on Monday ordered the Trump administration to restore all National Institutes of Health grants to UCLA, roughly $500 million, that the government suspended in July.

BREAKING: A federal judge has ordered Trump to restore $500 million in frozen UCLA NIH grants. The same judge, Rita F. Lin, previously ordered all UCLA NSF grants reinstated. Lin has now nearly entirely reversed Trump's July de-funding of UCLA research: www.latimes.com/california/s...

Screenshot from the cowardly clowns at the nyt. Headline and sub read Trump Administration Wields Its Full Toolbox to Bring Media to Heel ABC’s decision to “indefinitely” suspend Jimmy Kimmel’s late-night talk show illuminates the administration’s efficacy so far.

Pour one out for the @nytpitchbot.bsky.social. Satire is dead in a world where the real "reporting" looks like this

Controversial change

SpatialFuser: A Unified Deep Learning Framework for Spatial Multi-Omics Data Integrative Analysis https://www.biorxiv.org/content/10.1101/2025.09.14.676067v1

Next-gen spatial transcriptomic tools are helping overcome the challenge of degraded & FFPE samples.

Vizgen co-founder Jiang He explains how these advances are opening new doors for research in oncology, neuroscience & beyond:
www.biocompare.com/Editorial-Ar...

Postdoc position open!
Digital Pathology: Therapy-response prediction using spatial biology
University of Salzburg
Deadline: October 26th, 2025

We look forward to hearing from you!

www.plus.ac.at/biowissensch...

This, too

Opinion | We Are Watching a Scientific Superpower Destroy Itself

"We will never know what diseases might have been cured or what advances in technology might have been invented had the lights not gone out in the labs."
www.nytimes.com/2025/09/08/o...