Gonçalo Castelo-Branco

🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...

Fantastic Gioele!

Developing Brains on!

Photo: Cecilia Odlind

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...

@peruhlen.bsky.social
@ki.se

news.ki.se/from-a-crash...

Multi-omics Profiling of the Lateral Ventricle Choroid Plexus Reveals Developmental Cellular Remodeling, Early Immune Gene Activation, and a Novel Epithelial Subtype Healthy brain development and function highly depend on the choroid plexus. Temporal alterations in the cellular landscape and gene expression of choroid plexus cells can alter immune cell trafficking...

Ana Falcão's lab latest on multi-omics profiling of the Lateral Ventricle Choroid Plexus!
@icvs-uminho.bsky.social

www.biorxiv.org/content/10.1...

Deadline (September 2) approaching! Join us and start your lab at @ki.se!

Please RP.
We are thrilled to announce that our lab’s first preprint is out!
”Whole-genome single-cell multimodal history tracing to reveal cell identity transition”

We report HisTrac-seq, a multiomic single-cell molecular recording platform.
www.biorxiv.org/content/10.1...

New methods to map the progression of MS | Knut and Alice Wallenberg Foundation Wallenberg Scholar Gonçalo Castelo-Branco is seeking to discover what happens in the brain during the progression of multiple sclerosis (MS). His findings may lead to new ways of diagnosing and treati...

Wallenberg Scholar @gocastelobranco.bsky.social @ki.se is seeking to discover what happens in the brain during the progression of #multiplesclerosis (MS). His findings may lead to new ways of diagnosing and treating the disease earlier than is currently possible #research tinyurl.com/3kb22kkh

Join us at the FENS Single-Cell & Spatial Omics Winter School with:

@sarabiz86.bsky.social
@rongfan8.bsky.social
@gokcegroup.bsky.social
@gioelelamanno.bsky.social
@sj-marzi.bsky.social
@jplopez-atalaya.bsky.social
Ana Falcão
Florian Rosenberger
Gabriel Baró
Bosiljka Tasic
Barbara Treutlein

Image credit: @gloglita.bsky.social‬ @lifescienceeditors.bsky.social‬ captured DynaTag in action: a pA-Tn5 probe (multicoloured) binds an antibody (white), which binds p53 DNA-binding domain (green) on DNA (blue) within 2 nucleosomes

🧪Move over CUT&Tag, there’s a new #TranscriptionFactor mapping method in town.
Our newly developed DynaTag is faster, cleaner, more sensitive than #ChIPseq, #CUT&RUN and #CUT&Tag.
🔗 Our @natcomms.nature.com paper: www.nature.com/articles/s41...
🧵Let’s break down what makes DynaTag so powerful (1/7)

🚨 Don’t forget to register for #Neuroepi25!
⏳ The deadline is fast approaching - Thursday 7th August 2025.
This is your last chance to join; don't miss out on a fantastic meeting!
Click here to register➡️ bit.ly/4f5Zpbq
#FusionNeuro #FusionAgingResearch #FusionEpigenetics

12th Dev Brains:

@junyuecao.bsky.social @alainchedotal.bsky.social
@cecilecharrier.bsky.social
@trayon.bsky.social
Isabel Espinosa-Medina
Beatriz Rico
Michael Ziller
Dwight Bergles

news.ki.se/calendar/dev...

@hjerling-leffler.bsky.social
@ulrikakmarklund.bsky.social
@flallemend.bsky.social

Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social‬ @jasperjanssens.bsky.social‬ and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1

@carlstrom.bsky.social Clemens Ries, and Ting Sun rocking at #GLIA2025! And the launch of the Carlström lab!

Great to catch up with @rongfan8.bsky.social in Marseille, where we both end up for two completely unrelated conferences!

The call just opened!

ki.se/en/about-ki/...

You can apply to several departments simultaneously, check out which depts better fit your profile! Here is the call for our Department of Medical Biochemistry and Biophysics

ki.varbi.com/what:job/job...

Heads-up for major new faculty search at KI — with great startup packages and a wide range of subject areas.

Come and join us! Start your group at Karolinska Institutet @ki.se!

📢 Big news! #Neuroepi25 has just released the final programme!
👉 Check it out now on the conference website
✅ And don't forget to register - this is a conference you won’t want to miss!
Click here for more information: bit.ly/3SWoIlO

Have you registered yet for #ReThinkNeuroimmunology in October?
Speakers include @aleksdelab.bsky.social @labschaefer.bsky.social @annamolofskylab.bsky.social @itchdoctor.bsky.social @becherlab.bsky.social @gocastelobranco.bsky.social @miriammerad.bsky.social @kuchroolab.bsky.social & more

Thanks all speakers, chairs, panelists, MS patients and other participants that joined us at Karolinska Institutet @ki.se and that made this Symposium an unique thinktank (on the true sense of the word) on MS.

...and it is a wrap! 4 days of fantastic talks and brainstormings on the molecular and cellular mechanisms of multiple sclerosis and how this knowledge has been leading to disease-modifying treatments. And what we still don't know and where we are/should be moving towards.

Postdoc in Single Cell Genomics, Jens Hjerling-Leffler group, Karolinska Institutet Do you want to contribute to top quality medical research? The position is located within The Division of Molecular Neurobiology in the lab of Professor Jens Hjerling-Leffler at the Department of Medi

Postdoc positions available in my lab @ki.se Sweden - exciting science, fantastic environment and great quality of life. I take mentoring seriously - 7/7 postdocs that left my lab has faculty positions today. Existing datasets and funds to build new ones available. ki.varbi.com/en/what:job/...

Join us for the 2025 GRC Genome Architecture www.grc.org/genome-archi... @spp2202.bsky.social @jobdekker.bsky.social @metorrespadilla.bsky.social @jopkind.bsky.social @dimplenotani.bsky.social @stanleyqilab.bsky.social @andybelmont.bsky.social @fondufemittendorf.bsky.social @boyanbonev.bsky.social

Happy to share that I will kickstart my research group at @ki.se this autumn!🎉🎉 Are you interested in glial biology, using high-end tools for gene and cell programming to study metabolic and epigenetic interactions? Stay tuned! Will be 🔭 for RA, PhD-students & postdocs!
Let the journey begin! 🧬🧫🔬

Today!

Thanks for such a great meeting!

Night science is improvisations, openness, import/export, puzzle switching, hypothesis liabilities, anthropomorphisms, finding questions, contradictions & awe in science; as we discussed in the legendary Karolinska Institute. 🙏 @kragesteen-lab.bsky.social Christoph Ziegenhain & Rickard Sandberg

It was amazing to do a Night Science workshop today at the Karolinska Institute in Stockholm!