Michael Riedl

To recognise and celebrate @svobodalab.bsky.social's pivotal contribution to Woodstock Bio2 + Night Science, #TCTeAC, I am starting this "What Petr Svoboda did at Woodstock?" thread. If you were there - #contribute and #retweet.

"Petr Didn’t Submit an Abstract. #TCTeAC Submitted to Him."

Here’s why your blood vessels don’t burst under pressure Cells lining the blood vessels reorganize their inner structures to handle stressful boosts in pressure.

Our study on endothelial mechanics made the news! 🤩

Super nice and clear article on our findings and their implications.
www.snexplores.org/article/how-...

it appears your safe back-up post doc project wasn’t so risk free after all, mr. bond

Yes thanks :)

Amazing defense by @alisonkickuth.bsky.social! Congratulations on the beautiful thesis!

Can you add me?

Glad to see this one finally emerging :) congratulations Claire!

Interplay of actin nematodynamics and anisotropic tension controls endothelial mechanics Nature Physics - Blood flow through a vessel deforms vessel walls. Cells lining these walls sense the changes in pressure as blood flows and reorient their actin fibres in the direction of largest...

Very happy and excited to share our latest work linking actin nematodynamics and endothelial cell mechanics under anisotropic tension, now published in @natphys.nature.com ! rdcu.be/eigWi

@ipparis.bsky.social @polytechniqueparis.bsky.social

Looking for a student or postdoc!

Want to combine evolutionary analysis + structural modeling with in vitro biochemistry & fluorescence microscopy?
Help us uncover new protein-protein interactions — from in silico to in vitro.

Join us at @istaresearch.bsky.social 👉 looselab.org
🧬💡🔬🎡

Stretch-induced endogenous electric fields drive directed collective cell migration in vivo - Nature Materials Electric fields guide collective cell migration in developing embryos of Xenopus laevis via a voltage-sensitive phosphatase.

REPOSTING this here just to officially leave "the other place"

Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...

Very happy that our new paper on social distancing during epidemics has just come out in @pnas.org!

With @molinajohnj.bsky.social, Ryoichi Yamamoto, and Matthew S. Turner.

Understanding Nash epidemics | PNAS www.pnas.org/doi/10.1073/...

Well phrased, Sven.

Could you elaborate on one of them? A realistic pathway that leads to such a system. While I wish for such a system to be the status quo, I fail to imagine a pathway that doesn't rely on: if in a wrong system we all do the right thing will transform the system. Has this ever worked?

The belief that discoveries stem from and can be guided by lone geniuses, is at the core of this issue. Peer review and publishing follow the same pattern, where a few decide over the success of others, turning it into a lottery. What puzzles me is how do change this system from this point onward?

YouTube video by UCLA Broad Stem Cell Research Center Muscle cell fusing into a proto-muscle fiber

In fun news, a video of mine won the UCLA Broad Stem Cell Research Center's Imaging Competition!

You can see a muscle cell (a myoblast) fusing into a moving myotube. These myotubes mature to become our muscle fibers. They are beautiful cells! 🤩

www.youtube.com/watch?v=g6xK...

Job details Job details

The Image & Optics Facility @ Institute of Science and Technology Austria is expanding it’s image analysis services and has a vacant position for a service oriented *Image Analysis Specialist* with a strong interest for data infrastructure organization🔬🧑‍💻📈 - sharing is much appreciated

Excited about protein biochemistry, fluorescence microscopy, and image analysis? Curious how proteins drive bacterial division or define organelle identity? Join us at ISTA! Apply to the PhD program by Jan 8th: gradschool.ist.ac.at

Entropy is one of those formulas that many of us learn, swallow whole, and even use regularly without really understanding.

(E.g., where does that “log” come from? Are there other possible formulas?)

Yet there's an intuitive & almost inevitable way to arrive at this expression.

New paper out with the Kicheva group by S. Lehr and D. Bruckner! 🧪 Develops a new 2D neural tube organoid, and models its striking self-organized patterns! Key finding: patterning via 2-phase dynamics of BMP, which acts like a temporal relay balancing sequential fate decisions! bit.ly/3OJti4G

As promised, here a fast acquisition of a migrating cell videoed under a microscopy, look those membrane dynamics @ the leading edge !

Bonus: nuclear deformation once the cell rear snaps.
(Fluo nucleus, for the #fluorescencefriday)

@focalplane.bsky.social @cellcommlab.bsky.social #CellMigration 🧪🔬

I have moved to 🦋 as well ! Looking forward to reconnecting with old and initiating new science contacts here

Please add me!

Beautiful work!

Mix two motors of opposite polarity with microtubules and they will partition space !
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)

🌱🔬The most time-intensive and difficult paper of my PhD is now published in #mSystemsJ! I'm proud of this work and also how much I've grown since I first started this experiment. Read on to learn more about how the functions of bacterial communities impact plant growth and health. 👇

Neat!
What cells are these?

I thought #fluorescencefriday would be a good opportunity for my first post here. Here are some crazy actin dynamics imaged with TIRF

Can you add me? : )

Please add me :)

Please add me :)