Takeshi Imai

In June 2001, I arrived in SFO with a suitcase, a student visa, and disproportionate dreams.

My life since has been nothing but a dream.

My heart is with the international students in the US today.

23.05.2025 14:47 — 👍 44    🔁 6    💬 0    📌 0

Distinct synaptic plasticity rules operate across dendritic compartments in vivo during learning Synaptic plasticity underlies learning by modifying specific synaptic inputs to reshape neural activity and behavior. However, the rules governing which synapses will undergo different forms of plasti...

Our new paper is out in Science.

What is the synaptic plasticity rule in the brain, we asked. It turns out there are multiple, even within individual neurons.

Congrats Jake!

www.science.org/doi/10.1126/...

17.04.2025 23:46 — 👍 206    🔁 63    💬 2    📌 7

✨New paper from my lab out now in @cp-cell.bsky.social!
We identified pathways for airway protective reflexes—swallowing and coughing—in mice, driven by rare throat chemosensory cells that signal vagal nerves via channel synapses.
cell.com/cell/fulltex...

06.04.2025 02:22 — 👍 4    🔁 3    💬 9    📌 0

If you are interested in what happens deep in the brain during puberty, please check our new paper in Neuron. We visualize how nutritional status shapes sexual maturation in female mice: A flagship study by an excellent postdoc Teppei Goto. (1/N

24.02.2025 20:51 — 👍 6    🔁 2    💬 1    📌 0

How does neural activity control developmental synapse elimination? Here is a new review paper from the lab: Activity-dependent synaptic competition and dendrite pruning in developing mitral cells.
www.frontiersin.org/journals/neu...

27.01.2025 12:13 — 👍 5    🔁 4    💬 0    📌 0

SeeDB resources - Tetbow Videos Supplementary Videos associated with the eLife 2018 publication. Mitral/Tufted cell dendrites labelled with Tetbow (73.4MB). All the videos are free to download for non-commercial purposes. Press "po...

Feel free to use one from here if you like it: sites.google.com/site/seedbre...

14.12.2024 10:48 — 👍 3    🔁 0    💬 1    📌 0

A background in physics, and his own curiosity, have helped Dmitry Rinberg tackle the complexities of the neuroscience of smell. More on Rinberg sniffing out the mysteries of olfaction.

By Lina Zeldovich

www.thetransmitter.org/olfaction/sn...

11.12.2024 14:13 — 👍 46    🔁 13    💬 1    📌 6

Parallel labeled-line organization of sympathetic outflow for selective organ regulation in mice - Nature Communications How individual organs are specifically regulated by the sympathetic neurons at the cellular level remains not fully understood. Here, authors identify two molecularly distinct sympathetic pathways tha...

The sympathetic nervous system may control selective organs, but how this specificity is achieved is unknown. Our new study
@NatureComms www.nature.com/articles/s41...　uncovers a parallel labeled-line organization within the lower thoracic spinal cord. 1/

10.12.2024 10:55 — 👍 11    🔁 2    💬 1    📌 0

We also made a linear unmixing plugin for ImageJ/Fiji. You can use a conventional confocal for 7-color imaging: github.com/daichimori/L...
Paper: www.nature.com/articles/s41...
Additional codes at Github: github.com/TakeshiImaiLab
Addgene: www.addgene.org/Takeshi_Imai/

11.12.2024 01:47 — 👍 5    🔁 1    💬 0    📌 0

From our recent paper: 7-color Tetbow image of the neocortex🌈 We can distinguish hundreds of neurons based on the combinatorial expression of 7 FPs.
Here is the list of plasmids for Tetbow experiments if you are interested (all available from Addgene): sites.google.com/site/seedbre...

11.12.2024 01:46 — 👍 43    🔁 11    💬 3    📌 1

Hello, this is my first Bluesky post! We love neuroimaging🔬 Attached are covers from our lab featuring our favorite neurons, mitral cells in the olfactory bulb and L5 neurons in the neocortex. What's your #FavoriteNeuron?

11.12.2024 01:20 — 👍 4    🔁 0    💬 0    📌 0