Christian Brueffer's Avatar

Christian Brueffer

@brueffer.io.bsky.social

Consultant in #bioinformatics and #cancer applications @insilico.consulting (all things #genomics, #liquidbiopsy, and #workflows) β€’ πŸ‡ΈπŸ‡ͺ πŸ‡©πŸ‡ͺ β€’ 🧬πŸ–₯️ β€’ https://brueffer.io ORCiD: 0000-0002-3826-0989

1,610 Followers  |  1,202 Following  |  21 Posts  |  Joined: 08.09.2023  |  2.1457

Latest posts by brueffer.io on Bluesky

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πŸ“£πŸ“£ Cool job alert! The @bakerresearchau.bsky.social is recruiting up to 2 new PIs in Biomedical Data Science πŸ‘‰ www.seek.com.au/job/85989791...

You’d join an awesome institute in an incredible city (Melbourne, Australia) as well as partnerships like with @cam.ac.uk… you’ll also get to work with me 😁

25.07.2025 07:24 β€” πŸ‘ 18    πŸ” 18    πŸ’¬ 1    πŸ“Œ 1
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Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - BiRC - Bioinformatics Research Center, Aarhus University

πŸ“£ πŸ₯³ πŸ§‘β€πŸ’» Our department is hiring:

Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark

Deadline June 1st

Thanks for sharing!

mbg.au.dk/en/news-and-...

16.05.2025 12:35 β€” πŸ‘ 69    πŸ” 90    πŸ’¬ 0    πŸ“Œ 0
Short RNA-seq read alignment with minimap2

Minimap2-2.29 released with the support of short RNA-seq read alignment. More explanation and results here: lh3.github.io/2025/04/18/s...

18.04.2025 21:53 β€” πŸ‘ 29    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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GitHub - ACEnglish/truvari: Structural variant toolkit for VCFs Structural variant toolkit for VCFs. Contribute to ACEnglish/truvari development by creating an account on GitHub.

πŸš€ Truvari v5.0 is here! πŸŽ‰
What’s new?
πŸ”Ή Enhanced symbolic variant support for <DEL>, <DUP>, <INV>
πŸ”Ή Robust BND comparison for cross-representation SV matching
πŸ”Ή Improved SV sequence similarity & HUGE SV support
πŸ”Ή Cleaner UI & Revamped API

πŸ‘‰ More: github.com/ACEnglish/tr...
#Genomics #Bioinformatics

10.01.2025 13:43 β€” πŸ‘ 6    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

#ICYMI our deep dive into ALK1 biology, at the intersection between angiogenesis and immunology with clear implication for the targeting of immunomodulatory cues & cancer therapy!

13.03.2025 15:51 β€” πŸ‘ 0    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Thirty Years of BRCA1: Mechanistic Insights and Their Impact on Mutation Carriers Abstract. Thirty years ago, the cloning of the first breast cancer susceptibility gene, BRCA1, marked a milestone in our understanding of hereditary breast and ovarian cancers. This discovery initiate...

BRCA1 turned 30 πŸŽ‰
To celebrate, Jos Jonkers and I explored three decades of BRCA1 research - what we’ve learned about its biology, its role in tumorigenesis and future directions to improve the life of BRCA1 mutation carriers.
Now out in Cancer Discovery ⬇️: aacrjournals.org/cancerdiscov...

03.03.2025 09:26 β€” πŸ‘ 66    πŸ” 26    πŸ’¬ 1    πŸ“Œ 2
Index of /ReferenceSamples/giab/data_somatic/HG008/Liss_lab/analysis/NIST_HG008-T_somatic-stvar_DraftBenchmark_V0.1-20241219

Our first curated draft somatic structural variant benchmark for the new GIAB PDAC tumor cell line HG008-T is at ftp-trace.ncbi.nlm.nih.gov/ReferenceSam..., based on extensive short+long read sequencing data described in doi.org/10.1101/2024.... Feedback to improve future versions is very welcome!

20.12.2024 18:04 β€” πŸ‘ 15    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

Regular abstracts from #SABCS24 are out!

3407 pages of new breast cancer discoveries.

Find them here: sabcs.org/Portals/0/Do...

25.11.2024 23:41 β€” πŸ‘ 62    πŸ” 15    πŸ’¬ 0    πŸ“Œ 0

Added!

24.11.2024 13:59 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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two women are standing next to each other and one of them is saying i 'm so glad that you are here ALT: two women are standing next to each other and one of them is saying i 'm so glad that you are here

WOOT!
Just in time for #SABCS24 looks like @sabcs.bsky.social is officially on BlueSky!
cc: @maryamlustberg.bsky.social @drsgraff.bsky.social @stage4kelly.bsky.social @amjohnston.bsky.social @amybeumer.bsky.social @raalbany.bsky.social @hoperugo.bsky.social

21.11.2024 18:42 β€” πŸ‘ 18    πŸ” 5    πŸ’¬ 7    πŸ“Œ 2

Added!

20.11.2024 21:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Done!

20.11.2024 20:12 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Done! Sorry for the delay, notifications have been mad the last couple of days, so this one slipped through.

19.11.2024 06:41 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Done and welcome!

19.11.2024 06:31 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I dont care for either but my sambo has needs ;-)

17.11.2024 09:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Vegemite too by any chance?

17.11.2024 09:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Happy to join the bioinformatics + genomics starter. Thanks for the work!

16.11.2024 16:50 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Done!

16.11.2024 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Dear Colleagues,
For all of you in BlueSky, Greetings, We are Now Here!!
We invite you to Join & Follow OncoAlert at @oncoalert.bsky.social
Thank you for your support!

16.11.2024 13:31 β€” πŸ‘ 15    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0

For the #cancer / #oncology folks, OncoAlert is now on bsky: @oncoalert.bsky.social

16.11.2024 13:02 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
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single-cell computational methods Join the conversation

in case this is useful to someone in this massive platform migration: a starting pack for single-cell omics computational methods
go.bsky.app/GmS1cH

15.11.2024 11:11 β€” πŸ‘ 99    πŸ” 47    πŸ’¬ 15    πŸ“Œ 2

Inspired by the other amazing starter packs - here's one for cancer researchers!

I tried to make this broad - from immunology to genomics to cell biology and so much more..

This list also includes organizations & institutes supporting cancer researchers πŸ§ͺπŸ”¬βš•οΈπŸ©Ί

Hope its useful!

go.bsky.app/FEoaJMc

14.11.2024 21:44 β€” πŸ‘ 364    πŸ” 127    πŸ’¬ 102    πŸ“Œ 15

Thanks Johanna, could you add me as well? @laosaal.bsky.social would be another good addition.

15.11.2024 09:25 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I've created a Breast Cancer Starter Pack covering clinical oncology and research. Please share, and let me know in case you'd like to be added. #brca #breastcancer

go.bsky.app/6KXpPSy

15.11.2024 07:51 β€” πŸ‘ 13    πŸ” 7    πŸ’¬ 8    πŸ“Œ 0

We are actively recruiting for two open Computational Biology positions in our NGS group - both covered by this listing

www.ginkgobioworks.com/job-listings...

13.04.2024 16:55 β€” πŸ‘ 6    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0

Happy to have contributed a small part to this study. "Ultrahigh" #HER2 copy number by #dPCR or #RNAseq signals poor response to adjuvant #trastuzumab in breast cancer.

20.02.2024 09:00 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Hackathon - Improving the annotation of Galaxy resources for microbial This hackathon aims to improve the annotation of Galaxy resources for microbial data analysis and beyond

Online Hackathon to improve the annotation of @galaxyproject.bsky.social resources for microbial data analysis (and beyond): galaxyproject.org/events/2024-...
πŸ“† Date: March 11th - 15th
πŸ“ Location: Online via Zoom & chat. 2 daily stand-ups
πŸ‘₯ Participation: Free. Open to anyone, anywhere

19.02.2024 09:53 β€” πŸ‘ 5    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

Still a week to apply for this postdoc position to work with us on deep learning models for regulatory genomics πŸ‘‡πŸΌ

31.01.2024 07:34 β€” πŸ‘ 2    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

We will have a job ad for Japanese ecologists coming soon - any tips on breaking into the Japanese cluster here (i know its pretty big)? Good feeds or anything I can pop up in? (Other than, obviously, posting in Japanese).

30.01.2024 09:34 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Interested in breaking all your bioinformatic pipelines? Look no farther:

https://gatk.broadinstitute.org/hc/en-us/articles/6012243429531-GenotypeGVCFs-and-the-death-of-the-dot

17.01.2024 16:18 β€” πŸ‘ 22    πŸ” 8    πŸ’¬ 2    πŸ“Œ 0

@brueffer.io is following 20 prominent accounts