sn-RNA-seq analysis of wild-type and RTT rat brain. Nuclei were isolated from brains of wild-type rats and transgenic rats with loss of MECP2. (A) 10× single-cell RNA sequencing was performed, and single-cell profiles were obtained. (B) Gene expression profiles were plotted with UMAP, and several different neuronal subtypes were identified in various clusters as indicated. (C) A plot of DEGs between wild-type (WT) and RTT (MT) rat brain. (D) Plotted are the number of DEGs (upregulated and downregulated) in each neuronal subtype.
Abril Morales & co demonstrate that neurons lacking MECP2 show signs of elevated DNA damage and senescence transcriptional signatures, which could contribute to phenotypes in patients with Rett syndrome. doi.org/10.1242/dmm....
#RettSyndrome #DNADamage
17.10.2025 10:57 — 👍 2 🔁 1 💬 0 📌 0
I can’t stop replaying the #memories from our first-ever New York Memory Hub conference! So grateful to everyone who made it a success and inspired us with their research 🧠
17.10.2025 14:52 — 👍 12 🔁 4 💬 0 📌 0
So excited for you!!
29.09.2025 16:33 — 👍 1 🔁 0 💬 0 📌 0
Excited to share that I landed my dream job!🎉🎉🎉 The Pennington Lab will be opening at the University of British Columbia in January 2026!
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social
29.09.2025 16:31 — 👍 149 🔁 29 💬 29 📌 5
Endlessly grateful to my wonderful PhD mentor Lucas Pozzo-Miller and all past and current lab members. This project was a team effort that I was so lucky to be a part of!
02.06.2025 20:32 — 👍 2 🔁 0 💬 0 📌 0
Destynie Medeiros
🏆 Congratulations to the 2024 Outstanding Paper Prize winner for Research Articles: @destyniemedeiros.bsky.social, Karen Ayala-Baylon, Hailey Egido-Betancourt, Christopher Chapleau and Wei Li. Read our Editorial to learn more about the winners & their research. doi.org/10.1242/dmm....
02.06.2025 18:55 — 👍 2 🔁 1 💬 2 📌 1
Collage that includes three presenters on the left, and on the right is a group photo of Cai Lab attendees.
The Cai Lab is at @mpfneuro.bsky.social's Emerging Neurotechnology course this week, running a #Miniscope workshop. The course kicked off Monday with an AMAZING keynote by Nobel Laureate @stefanhelllabs.bsky.social.
Looking forward to the rest of the week’s activities! 🤓 #Neuroskyence
16.04.2025 20:47 — 👍 30 🔁 5 💬 1 📌 0
Congratulations to you and the lab! Well deserved!!
11.04.2025 19:31 — 👍 1 🔁 0 💬 1 📌 0
NIDA notice of award
I am so happy to share that our lab was awarded our first (!!!) R01, the Stephen Katz R01 through NIDA! This award will allow our lab to expand into the fields of reward and addiction, where we will examine the prefrontal GABAergic circuits of adaptive and maladaptive reward seeking! We're hiring!
10.04.2025 16:46 — 👍 122 🔁 4 💬 15 📌 0
UBC's Department of Psychology is a leader in research and scholarship— with diverse rankings placing us among the strongest departments in the world. psych.ubc.ca
Assistant Professor @ UT Southwestern
PI of Heyward Nutritional & Behavioral Epigenetics Lab (https://www.frankieheywardlab.com/)
Broadly Studying: The Epigenetic Control of Appetite 🧠🧬🍔🤤
Web development, data management and visualizations. Consulting services for scientific and r&d communities. https://www.researchelements.org/
Artist, Phd
All art posted is by me. Let me know in the comments your thoughts and impressions
DM me If you are interested in purchasing anything I post. I only sell the original work and generally are priced about $60
Director, Penn State Neuroscience Institute - University Park; Huck Early Career Chair in Neurobiology and Neural Engineering, Departments of Biology & Biomedical Engineering.
Disease Models & Mechanisms - discovery for human health. A
@biologists.bsky.social Open Access journal that publishes human disease research.
Neuroscience Research Director
@ French Institute of Health (INSERM)
@ University of Bordeaux
I post mainly about Neuroscience, Machine Learning, Complex Systems, or Stats papers.
Working on neural learning /w @auksz.bsky.social CCNB/BCCN/Free University Berlin.
I also play bass in a pop punk band:
https://linktr.ee/goodviewsbadnews
Scientist, artist, educator, chef, fisherman, outdoor enthusiast, bookworm, linguist, peacemaker, volunteer, etc. in no particular order.
Please don't ask because I will not date you, I will not send you money, and I will not be your disciple. Thanks.
Guest Researcher with the focus on #Autism Spectrum Disorders and #Biolinguistics at Universität Potsdam
https://www.researchgate.net/profile/Candice_Chi_Hang_Cheung
Neuroscientist, Associate Professor, Lerner Lab. Dopamine and basal ganglia circuits controlling reinforcement learning and decision-making. Open/inclusive science. Happy working mom of 3.
Yale ➡️ UCSF ➡️ Stanford ➡️ Northwestern
lernerlab.org
Neuroscientist at UAB interested in molecular and genetic mechanisms in brain function. Director, UAB Comprehensive Neuroscience Center.
Scientist, mother, perpetual learner. Assistant Professor, Structural Biologist, Advocate, and Speaker. Views my own.
signal @starbic.01
www.starbirdlab.com
Scientist 👩🔬 & EPFL Prof 🇨🇭 | DeepLabCut.org , 🦓 cebra.ai | neuroscience & ML 🧠 mackenziemathislab.org | ✨CSO at Kinematik.ai | occasionally 🐦⬛birds/🌱outdoors/🍣food/👠fashion
Slowly becoming a neuroscientist.
EiC @elife.bsky.social
neuroscientist, psychiatrist, writer
optogenetics.org
karldeisseroth.org
https://www.amazon.com/Projections-Story-Emotions-Karl-Deisseroth/dp/1984853694
The largest nonprofit of scientists & physicians devoted to understanding the brain & nervous system. SfN.org
