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And here it is! Our study in clonal hematopoiesis and Alzheimer’s disease — product of 5 years’ gestation. urldefense.proofpoint.com/v2/url?u=htt...
02.07.2025 15:17 — 👍 22 🔁 8 💬 4 📌 1
A lot of fun teaming up with Hsin and Howard on this, with key contributions from @ruochiz.bsky.social, @zchiang.bsky.social, and @jbuenrostro.bsky.social on the tech dev and @mattjones.bsky.social, Natasha Weiser, and Paul Mischel on the ecDNA analysis. (5/5)
18.04.2025 18:36 — 👍 5 🔁 2 💬 1 📌 0
We also apply SPACE-seq to an archived glioblastoma sample, showing that SPACE-seq works well with clinical samples and can detect extrachromosomal DNA amplifications and somatic mutations. (4/5)
18.04.2025 18:36 — 👍 2 🔁 0 💬 1 📌 0
Mitochondrial DNA is captured as well, enabling mtscATAC (a lineage tracing technique previously developed by @caleblareau.bsky.social, @leifludwig.bsky.social, and @bloodgenes.bsky.social) to be applied spatially. (3/5)
18.04.2025 18:36 — 👍 2 🔁 0 💬 1 📌 0
The main idea here is that by tagmenting tissue sections with polyA-tailed adapters, instead of the standard ATAC-seq adapters, we can use spatial transcriptomics slides from @10xgenomics.bsky.social to capture both ATAC and RNA data with spatial resolution. (2/5)
18.04.2025 18:36 — 👍 5 🔁 1 💬 1 📌 0
Today we're thrilled to announce our 2024 #HannaGrayFellows! Please join us in welcoming and celebrating these outstanding early career scientists!
08.01.2025 14:24 — 👍 119 🔁 46 💬 1 📌 38
Co-founder of Grant Witness: https://grant-witness.us
Epidemiologist. Attorney. Social, legal, and environmental determinants of health @ Harvard TH Chan School of Health.
On Signal: sdelaney.84
science reporter covering biomedical research at Nature | proudly Ukrainian 🇺🇦
maxkozlov.com
signal: mkozlov.01
Mathematician at UCLA. My primary social media account is https://mathstodon.xyz/@tao . I also have a blog at https://terrytao.wordpress.com/ and a home page at https://www.math.ucla.edu/~tao/
Assistant prof at UCLA using the Bayes for the genomes https://pimentellab.com
Neuroimmunologist studying MS, autism, Alzheimer's disease, and brain injury at the University of Virginia. Father of two. Fan of Philly sports and US soccer.
www.lukenslab.com
Heme Chief at Stanford. Physician Scientist studying myeloid malignancies. Views my own.
Incoming Assistant Professor @Yale School of Medicine/former musician/aspiring scientist/ultra-foodie/Peyton Manning mega-fan
Curious about plants and their interaction with the environment. Stanford Professor and HHMI Investigator. Opinions are my own.
Postdoc in Ralph DeBerardinis' Lab and Neonatologist at UT Southwestern (UTSW) via Harvard/MIT MD-PhD, Harvard Pediatric Residency, UTSW Neonatology Fellowship | STAT Wunderkind, ASCI E-Gen Award, BWF CAMS
Studying #metabolism, #mitochondria, #peroxisomes
B cell biologist at Rockefeller University and @hhmi.bsky.social. Opinions are my own.
www.germinal.center
Pediatrician-scientist & genome editor • Assistant Professor of Pediatric Allergy/Immunology @UCSF • @Doudna_Lab and Puck Lab
News from Jennifer Doudna's lab at UC Berkeley, Innovative Genomics Institute. Tweets from lab members and not Jennifer Doudna unless signed JD. Tweets represent personal views only.
doudnalab.org
Director, Marc and Jennifer Lipschultz Precision Immunology Institute: https://icahn.mssm.edu/research/immunology
Harnessing the innate immune system for novel therapies against cancer & inflammatory diseases: https://www.meradlab.org/
Assistant Professor | Harvard Stem Cell & Regenerative Biology | Immunologist and Tissue biologist | Proud mama
www.ruthfranklinlab.com
CS PhD Candidate at Stanford. Working at the intersection of Machine Learning, Regulatory Genomics, and Complex Disorders
Researching immunology, metabolism, and cancer, and caring for patients with lymphoma at MSKCC (www.vardhanalab.com). Opinions are my own.
Professor at KTH, NY Genome Center, SciLifeLab, working on functional genomics and human genetics.
Dedicated to drug discovery, enthralled by science. 5 kids. She. SAB Recursion. Founder SyzOnc. Lab at Broad Institute. Opinions my own.
HHMI Hanna H. Gray Fellow; Studying RNA and DNA organization in nuclear bodies and the cell with SPRITE/genomics tools. Postdoc in Brangwynne Lab @Princeton. Ph.D. in Guttman Lab @Caltech
HFSP Postdoc in the Wysocka and Jarosz labs @Stanford. Aiming to understand physiological protein assemblies. Alum of ETH Zürich.
