Ken Milne MD

RFK Jr.: “We Need to Stop Trusting Experts” A recent recommendation by RFK Jr.’s vaccine advisory committee shows why trusting experts is still a good idea

pauloffit.substack.com/p/rfk-jr-we-...

The top US health director who stood up for science — and was fired Susan Monarez is part of Nature’s 10, a list of people who shaped science in 2025.

www.nature.com/articles/d41...

Under RFK Jr., the CDC provides a megaphone to the anti-vaccine movement Common anti-vaccine talking points were on display as the CDC’s immunization advisers repealed a hepatitis B birth vaccine recommendation and scrutinized the childhood schedule.

Under RFK Jr., the CDC provides a megaphone to the anti-vaccine movement www.washingtonpost.com/health/2025/...

Thanks for sharing. I’m interested in this space. Could we connect?

Breaking news on non-inferiority trials.

thesgem.com/2025/12/sgem... #MemeMonday

AI reviewers are here — we are not ready Artificial intelligence promises rapid and polite feedback on papers — but we must first review the reviewer.

www.nature.com/articles/d41... #MedSky

Yep…

SGEM#495: Tell Me Lies, Tell Me Sweet Little Lies – Reporting of Noninferiority Margins on ClinicalTrials.gov. Podcast Episode · The Skeptics Guide to Emergency Medicine · 2025-12-06 · 25m

podcasts.apple.com/ca/podcast/t... @epiellie.bsky.social

SGEM podcast on non-inferiority reporting is now available. Listen to Jestin, and I talk nerdy instead of hanging out by the pool in Key West. #EBM
thesgem.com/2025/12/sgem... #MedSky @dennisrenmd.bsky.social

SGEM#495: Tell Me Lies, Tell Me Sweet Little Lies – Reporting of Noninferiority Margins on clinicaltrials.gov

thesgem.com/2025/12/sgem...

Recorded in Key West at the CCME Year in Review course with Dr. Jestin Carlson. #MedSky

Rethinking statistical significance From medicine to economics, significance testing misleads. Estimation offers a clearer way forward.

reason.com/2025/12/01/o...

🧠🪱🗣️💉🩺✋🏻

CDC panel recommends delaying birth dose of hepatitis B vaccine The CDC's ACIP panel voted to recommend delaying the birth dose of the hepatitis B vaccine, ending a policy that has reined in the virus.

www.statnews.com/2025/12/05/c...

Analysis of the latest ACIP meeting at the CDC: Vaccines—and rigorous science—are increasingly under attack. A close look at how the CDC’s vaccine advisory committee under RFK Jr. again changed high-stakes recommendations without solid evidence.

insidemedicine.substack.com/p/analysis-o... @dennisrenmd.bsky.social @jeremyfaust.bsky.social

Reporting of Noninferiority Margins on ClinicalTrials.gov This systematic review evaluates the proportion, time point, and consistency between registration and publication of noninferiority margin reporting.

Tomorrow on the SGEM (recorded in Key West, Florida), we review an SRMA on the reporting of non-inferiority margins. While other people were lying around in the sun, we were talking nerdy.
jamanetwork.com/journals/jam...

Glyphosate safety article retracted eight years after Monsanto ghostwriting revealed in court Credit: Mike Mozart/Flickr (CC BY 2.0) A review article concluding the weed killer Roundup “does not pose a health risk to humans” has been retracted eight years after documents released in a court…

Glyphosate safety article retracted eight years after Monsanto ghostwriting revealed in court retractionwatch.com/2025/12/04/g...

They have many other excellent courses courses.ccme.org

Just recorded a great SGEM podcast with Dr. Jestin Carlson in Key West while at the CCME year-in-review course.

Great location, wonderful attendees, ~250 articles reviewed & an amazing faculty...
courses.ccme.org/course/ema #MedSky

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A couple of good videos.

Ethics: AI policy

www.journals.uchicago.edu/journals/et/... #MedSky

What course will you go to in 2026

courses.ccme.org/course/ema

Patients with chronic abdominal pain and ED utilization.
thesgem.com/2025/11/sgem...

#PaperinaPic by @kirstychallen.bsky.social

@rickpescatore.bsky.social #MedSky

Having a great time in Key West reviewing >200 recent publication with >100 clinicians & amazing faculty.

Showing them critical appraisal of the medical literature.

Check out next years 8 fabulous locations.
courses.ccme.org/course/ema

The case of the fake references in an ethics journal Many would-be whistleblowers write to us about papers with nonexistent references, possibly hallucinated by artificial intelligence. One reader recently alerted us to fake references in … an ethics…

Irony...
retractionwatch.com/2025/12/02/f...

The Cochrane reviews on HPV vaccines - Part 1 The vaccines’ effects on the community

The Cochrane reviews on HPV vaccines - Part 1
open.substack.com/pub/trustthe...

@rickpescatore.bsky.social
thesgem.com/2025/11/sgem... #MemeMonday #EBM #MedSky #FOAMed

"Some scientific papers have errors so obvious that they become instant social media meme fodder (and they should be struck from the scientific record as soon as possible)."
nobreakthroughs.substack.com/p/riding-the...

Absence of evidence is not evidence of absence – and that affects what scientific journals choose to publish Researchers design studies that might disprove what’s called their null hypothesis – the opposite of the claim they’re interested in exploring.

Discussion of the null hypothesis and Type I Errors.
theconversation.com/absence-of-e...

Robert F. Kennedy, Jr. is definitely coming for your vaccines, part 5: VAERS and a useful idiot at the FDA In the sadly continuing story of how Health and Human Services Secretary RFK Jr. is working to eliminate vaccines, we look at a useful idiot, Dr. Vinay Prasad, and how he is weaponizing dead children

sciencebasedmedicine.org/rfk-jr-is-de...