i always wish the main sites for neddylation involved the sequence FLANDERS
07.12.2025 22:14 β π 3 π 0 π¬ 0 π 0@upbeatprof.bsky.social
And remember: you must never, under any circumstances, despair. To hope and to act, these are our duties in misfortune. -- Boris Pasternak, Doctor Zhivago Skeets are my own+do not reflect views of employers past or present.
i always wish the main sites for neddylation involved the sequence FLANDERS
07.12.2025 22:14 β π 3 π 0 π¬ 0 π 0Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling https://www.biorxiv.org/content/10.64898/2025.12.06.692499v1
07.12.2025 22:02 β π 1 π 1 π¬ 0 π 0Steve Leininger holding up phone booted into LDOS
Steve Leininger, the father of the TRS-80, running TRS-80 software on his phone.
07.12.2025 21:16 β π 133 π 26 π¬ 1 π 3malicious compliance: kids edition
07.12.2025 14:41 β π 3 π 0 π¬ 0 π 0some people have a real problem with the concept that not everything is made for them, and instead assess that participation in such efforts reflects skill issues, moral defects, or similar.
07.12.2025 03:01 β π 1 π 0 π¬ 1 π 0an old copy of the memoir "All Creatures Great and Small," by James Herriott
my thought on one of tonight's Bluesky topics.
07.12.2025 02:55 β π 0 π 0 π¬ 0 π 0Just been reminded of another of my all-time favourites, Ian Curtis rides a rollercoaster...
08.10.2024 16:36 β π 1172 π 229 π¬ 18 π 30i hate this, thank you for the recommendation that's going to give me nightmares
07.12.2025 01:52 β π 1 π 0 π¬ 0 π 0their first scene together after switching faces, so awesome. basically Heat's diner scene, John Woo style
06.12.2025 21:57 β π 1 π 0 π¬ 0 π 0"no more drugs for that man" was in no way a friend's favorite saying during college
06.12.2025 21:32 β π 1 π 0 π¬ 0 π 0i mean, cmon, Margaret Cho kicks the crap out of one of the bad guys
06.12.2025 21:20 β π 3 π 0 π¬ 1 π 0there's more movie in the first ten minutes than in the entirety of most Marvel movies
06.12.2025 21:17 β π 4 π 1 π¬ 2 π 0this movie is the peak of Hollywood John Woo and also Nic Cage and also John Travolta.
06.12.2025 21:14 β π 4 π 0 π¬ 2 π 0awesome. Face/Off is back on Netflix.
(remembering an only-OK first date for coffee, that turned epic when some idiot needed to be taken to the ER, anyway we watched Face/Off at...some point)
Onion headline: Frank Gehry No Longer Allowed To Make Sandwiches for Grandkids, with a picture of a βsandwichβ that looks like a Frank Gehry building
RIP Frank Gehry
05.12.2025 19:32 β π 198 π 46 π¬ 1 π 1from yolk to yoke
05.12.2025 23:33 β π 11 π 1 π¬ 0 π 0for my money
theonion.com/shaq-misses-...
man, Alien Covenant is... not good.
05.12.2025 01:00 β π 1 π 0 π¬ 0 π 0i have never felt more like the product
04.12.2025 15:09 β π 1 π 0 π¬ 0 π 0Kohler can make the funniest captcha of all time
04.12.2025 03:34 β π 1 π 1 π¬ 0 π 0It's important to have a job that makes a difference, boys. That's why I manually masturbate caged animals for artificial insemination.
03.12.2025 23:52 β π 0 π 0 π¬ 1 π 0ughh I'm really, really sorry
03.12.2025 23:13 β π 1 π 0 π¬ 0 π 0rest in peace.
youtu.be/o1emR12qb_Y
One of the all-time greats - guitarist, songwriter, producer, icon. Rest easy, Steve. variety.com/2025/music/n...
03.12.2025 22:09 β π 235 π 73 π¬ 6 π 56this is the worst book I've ever downloaded. my storage is embarrassed for me
03.12.2025 21:57 β π 5 π 0 π¬ 0 π 0Anyone at Harvard need a super well-trained undergrad next semester? Cell culture, molecular bio, microscopy and data analysis. Very careful and rigorous. Good lab citizen. Ready to jump in and learn/get some data! Has light course load, so plenty of time for research! Let me know of any leads!
03.12.2025 19:15 β π 11 π 9 π¬ 0 π 0this was a surprisingly long journey!
03.12.2025 18:14 β π 1 π 0 π¬ 0 π 0time for a second edition?? π€π
03.12.2025 15:28 β π 0 π 0 π¬ 1 π 0Hi #bioinformatics folk, I want to quickly extract metagenome reads that map to medium-sized piles of reference genomes (100s-1000s, but not 10_000s). I don't _necessarily_ care about the exact position. I'm using minimap2 right now but it's kinda choking on 1000 microbial genomes at once. Thoughts?
02.12.2025 19:09 β π 6 π 6 π¬ 6 π 0